diff --git a/docs/fundamentals/flow/topologies.md b/docs/fundamentals/flow/topologies.md
index 3eaa6d7cda626..fcead6121beea 100644
--- a/docs/fundamentals/flow/topologies.md
+++ b/docs/fundamentals/flow/topologies.md
@@ -147,7 +147,7 @@ You can restrict the visible devices in round-robin assignment using `CUDA_VISIB
 | 0          | 4          |
 
 
-You can restrict the visible devices in round-robin assignment by assigning a list of devices ids `CUDA_VISIBLE_DEVICES=RR1,3`. This creates the following assignment:
+You can restrict the visible devices in round-robin assignment by assigning the list of device IDs to `CUDA_VISIBLE_DEVICES=RR1,3`. This creates the following assignment:
 
 | GPU device | Replica ID |
 |------------|------------|
@@ -157,6 +157,16 @@ You can restrict the visible devices in round-robin assignment by assigning a li
 | 3          | 3          |
 | 1          | 4          |
 
+You can also refer to GPUs by their UUID. For instance, you could assign a list of device UUIDs `CUDA_VISIBLE_DEVICES=RRGPU-0aaaaaaa-74d2-7297-d557-12771b6a79d5,GPU-0bbbbbbb-74d2-7297-d557-12771b6a79d5,GPU-0ccccccc-74d2-7297-d557-12771b6a79d5,GPU-0ddddddd-74d2-7297-d557-12771b6a79d5`.
+Check [CUDA Documentation](https://docs.nvidia.com/cuda/cuda-c-programming-guide/index.html#env-vars) to see the accepted formats to assign CUDA devices by UUID.
+
+| GPU device | Replica ID |
+|------------|------------|
+| GPU-0aaaaaaa-74d2-7297-d557-12771b6a79d5          | 0          |
+| GPU-0bbbbbbb-74d2-7297-d557-12771b6a79d5          | 1          |
+| GPU-0ccccccc-74d2-7297-d557-12771b6a79d5          | 2          |
+| GPU-0ddddddd-74d2-7297-d557-12771b6a79d5          | 3          |
+| GPU-0aaaaaaa-74d2-7297-d557-12771b6a79d5          | 4          |
 
 ## Distributed replicas
 
diff --git a/jina/orchestrate/deployments/__init__.py b/jina/orchestrate/deployments/__init__.py
index 298945c841157..cd5eb67219b8f 100644
--- a/jina/orchestrate/deployments/__init__.py
+++ b/jina/orchestrate/deployments/__init__.py
@@ -732,7 +732,7 @@ def _parse_devices(value: str, num_devices: int):
         :return: slice
         """
 
-        all_devices = range(num_devices)
+        use_uuids = False
         if re.match(WRAPPED_SLICE_BASE, value):
             value = value[1:-1]
 
@@ -742,13 +742,28 @@ def _parse_devices(value: str, num_devices: int):
                 parts = value.split(':')
 
                 if len(parts) == 1:
-                    # slice(stop)
+                    try:
+                        int(parts[0])
+                    except:
+                        use_uuids = True
+                    if use_uuids:
+                        return parts
                     parts = [parts[0], str(int(parts[0]) + 1)]
-                # else: slice(start, stop[, step])
             else:
-                return [int(p) for p in parts]
+                # try to detect if parts are not numbers
+                try:
+                    int(parts[0])
+                except:
+                    use_uuids = True
+
+                if not use_uuids:
+                    return [int(p) for p in parts]
+                else:
+                    return parts
         else:
             parts = []
+
+        all_devices = range(num_devices)
         return all_devices[slice(*[int(p) if p else None for p in parts])]
 
     @staticmethod
@@ -776,10 +791,11 @@ def _roundrobin_cuda_device(device_str: str, replicas: int):
 
             selected_devices = []
             if device_str[2:]:
-                for device_num in Deployment._parse_devices(
+
+                for device in Deployment._parse_devices(
                     device_str[2:], num_devices
                 ):
-                    selected_devices.append(device_num)
+                    selected_devices.append(device)
             else:
                 selected_devices = range(num_devices)
             _c = cycle(selected_devices)
diff --git a/jina/serve/stream/__init__.py b/jina/serve/stream/__init__.py
index 1b4ca18bb2cf1..c5b4f3562d353 100644
--- a/jina/serve/stream/__init__.py
+++ b/jina/serve/stream/__init__.py
@@ -1,4 +1,3 @@
-import argparse
 import asyncio
 from typing import (
     TYPE_CHECKING,
diff --git a/tests/unit/orchestrate/deployments/test_cuda_assignment.py b/tests/unit/orchestrate/deployments/test_cuda_assignment.py
index af384f18aee77..55b72e2f9dd34 100644
--- a/tests/unit/orchestrate/deployments/test_cuda_assignment.py
+++ b/tests/unit/orchestrate/deployments/test_cuda_assignment.py
@@ -27,9 +27,13 @@ def cuda_total_devices(request):
         ['RR1:', 5, {0: 1, 1: 2, 2: 1, 3: 2, 4: 1}, 3],
         ['RR0:2', 5, {0: 0, 1: 1, 2: 0, 3: 1, 4: 0}, 3],
         ['RR1:2', 2, {0: 1, 1: 1}, 3],
+        ['RR2', 2, {0: 2, 1: 2}, 3],
+        ['RRUUID1', 2, {0: 'UUID1', 1: 'UUID1'}, 3],
         ['RR1:2', 1, {0: 1}, 3],
         ['RR0,2,3', 3, {0: 0, 1: 2, 2: 3}, 4],
         ['RR0,2,3', 5, {0: 0, 1: 2, 2: 3, 3: 0, 4: 2}, 4],
+        ['RRUUID1,UUID2,UUID3', 5, {0: 'UUID1', 1: 'UUID2', 2: 'UUID3', 3: 'UUID1', 4: 'UUID2'}, 4],
+        ['RRGPU-0aaaaaaa-74d2-7297-d557-12771b6a79d5,GPU-0bbbbbbb-74d2-7297-d557-12771b6a79d5,GPU-0ccccccc-74d2-7297-d557-12771b6a79d5,GPU-0ddddddd-74d2-7297-d557-12771b6a79d5', 5, {0: 'GPU-0aaaaaaa-74d2-7297-d557-12771b6a79d5', 1: 'GPU-0bbbbbbb-74d2-7297-d557-12771b6a79d5', 2: 'GPU-0ccccccc-74d2-7297-d557-12771b6a79d5', 3: 'GPU-0ddddddd-74d2-7297-d557-12771b6a79d5', 4: 'GPU-0aaaaaaa-74d2-7297-d557-12771b6a79d5'}, 4],
     ], indirect=['cuda_total_devices']
 )
 def test_cuda_assignment(device_str, replicas, expected, cuda_total_devices):