diff --git a/CHANGELOG.md b/CHANGELOG.md
index 807fe18cbd6a..c4895d250a34 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -7,6 +7,7 @@
 ### Fixes
 
 - `[@jest/expect-utils]` Fix deep equality of ImmutableJS Lists ([#12763](https://github.com/facebook/jest/pull/12763))
+- `[jest-core]` Do not collect `SIGNREQUEST` as open handles ([#12789](https://github.com/facebook/jest/pull/12789))
 
 ### Chore & Maintenance
 
diff --git a/packages/jest-core/src/__tests__/collectHandles.test.js b/packages/jest-core/src/__tests__/collectHandles.test.js
index b0628157af00..9b79c5e6e280 100644
--- a/packages/jest-core/src/__tests__/collectHandles.test.js
+++ b/packages/jest-core/src/__tests__/collectHandles.test.js
@@ -6,6 +6,7 @@
  *
  */
 
+import crypto from 'crypto';
 import {promises as dns} from 'dns';
 import http from 'http';
 import {PerformanceObserver} from 'perf_hooks';
@@ -67,6 +68,22 @@ describe('collectHandles', () => {
     );
   });
 
+  it('should not collect the SIGNREQUEST open handle', async () => {
+    const handleCollector = collectHandles();
+
+    const key =
+      '-----BEGIN PRIVATE KEY-----\r\nMC4CAQAwBQYDK2VwBCIEIHKj+sVa9WcD' +
+      '/q2DJUJaf43Kptc8xYuUQA4bOFj9vC8T\r\n-----END PRIVATE KEY-----';
+    const data = Buffer.from('a');
+    crypto.sign(null, data, key);
+
+    const openHandles = await handleCollector();
+
+    expect(openHandles).not.toContainEqual(
+      expect.objectContaining({message: 'SIGNREQUEST'}),
+    );
+  });
+
   it('should collect handles opened in test functions with `done` callbacks', done => {
     const handleCollector = collectHandles();
     const server = http.createServer((_, response) => response.end('ok'));
diff --git a/packages/jest-core/src/collectHandles.ts b/packages/jest-core/src/collectHandles.ts
index 61afcf7fd846..5e69fd920e71 100644
--- a/packages/jest-core/src/collectHandles.ts
+++ b/packages/jest-core/src/collectHandles.ts
@@ -72,7 +72,8 @@ export default function collectHandles(): HandleCollectionResult {
         type === 'PerformanceObserver' ||
         type === 'RANDOMBYTESREQUEST' ||
         type === 'DNSCHANNEL' ||
-        type === 'ZLIB'
+        type === 'ZLIB' ||
+        type === 'SIGNREQUEST'
       ) {
         return;
       }