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Hello, I'm a researcher in the field of electrical and information engineering, biophysics, soft matter and synthetic biology. Since spring 2023 I lead the bio-inspired computation lab at Kiel University.

I obtained my PhD in the Dimova Lab. I did my first postdoc with Reinhard Lipowsky, and a second postdoc with Neha Kamat. I mostly work experimentally and use software tools to analyze and understand data acquired in the lab. Recently I have developed some interest in using computer simulations. Over time I will upload more tools and scripts I have used.

Calculate area, volume and adhesion energies from confocal images of adhering vesicles

PEO-b-PBD Diblock copolymer example bilayer structure, topology, force field, and simulation parameter for use with GROMACS 2020

Full publication list at Google Scholar, e-mail and twitter @ja_steinkuehler.

First author publications

  1. Improving Cell-Free Expression of Model Membrane Proteins by Tuning Ribosome Cotranslational Membrane Association and Nascent Chain Aggregation, Steinkühler, J., Peruzzi, J. A., Krüger, A., Villaseñor, C. G., Jacobs, M. L., Jewett, M. C., & Kamat, N. P. ACS Synthetic Biology (2023) Full Text
  2. PEO-b-PBD Diblock Copolymers Induce Packing Defects in Lipid/Hybrid Membranes and Improve Insertion Rates of Natively Folded Peptides, Steinkühler, J., Jacobs, M. L., Boyd, M. A., Villaseñor, C. G., Loverde, S. M., & Kamat, N. P. Biomacromolecules 23, 4756−4765 (2022) Full Text
  3. Superelasticity of Plasma-and Synthetic Membranes Resulting from Coupling of Membrane Asymmetry, Curvature, and Lipid Sorting, Steinkühler, J., Fonda, P., Bhatia, T., Zhao, Z., Leomil, F. S., Lipowsky, R., & Dimova, R. Advanced Science, 2102109 (2021) Full Text
  4. Energy Dissipation at Interfaces Drives Multicompartment Remodeling, J. Steinkühler, N.H. Kamat (2020) Chem Full Text
  5. Controlled division of cell-sized vesicles by low densities of membrane-bound proteins, J. Steinkühler, R.L. Knorr, Z. Zhao, T. Bhatia, S.M. Bartelt, S. Wegner, R. Dimova and R. Lipowsky, Nature Communications, 11(1), 1-11 (2020) Full Text Press release
  6. Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density, J. Steinkühler, E. Sezgin, I. Urbančič, C. Eggeling, R. Dimova Communications Biology, Volume 2, 337 2019 Full Text
  7. Membrane fluctuations and acidosis regulate cooperative binding of “marker of self” CD47 with macrophage checkpoint receptor SIRPα, J. Steinkühler, B. Różycki, C. Alvey, R. Lipowsky, T.R. Weikl, R. Dimova., D. E. Discher J Cell Sci, 132(4) 2019 Full Text with Featured first-author interview
  8. Light guided motility of a minimal synthetic cell, S. M. Bartelt*, J. Steinkühler*, R. Dimova, S. V. Wegner *equal contribution Nano Letters, 18(11), pp.7268-7274, 2018 Full Text
  9. Charged giant unilamellar vesicles prepared by electroformation exhibit nanotubes and transbilayer lipid asymmetry, J Steinkühler, P. De Tillieux, R.L. Knorr, R. Lipowsky, R. Dimova Scientific Reports 8 (1), 11838, 2018 Full Text
  10. Modulating Vesicle Adhesion by Electric Fields, J. Steinkühler, J. Agudo-Canalejo, R. Lipowsky, R. Dimova Biophysical Journal 111 (7), 1454-1464, 2016 Full Text
  11. Characterization of Double Layer Alterations Induced by Charged Particles and Protein–Membrane Interactions Using Contactless Impedance Spectroscopy, J. Steinkühler, V. Charwat, L. Richter, P. Ertl The Journal of Physical Chemistry B 116 (35), 10461-10469, 2012 Full Text