diff --git a/CODEOWNERS b/CODEOWNERS
index 382fbffecaa3a..0e2934b1f4932 100644
--- a/CODEOWNERS
+++ b/CODEOWNERS
@@ -1742,6 +1742,7 @@ build.json @home-assistant/supervisor
 /tests/components/youless/ @gjong
 /homeassistant/components/youtube/ @joostlek
 /tests/components/youtube/ @joostlek
+/homeassistant/components/zabbix/ @kruton
 /homeassistant/components/zamg/ @killer0071234
 /tests/components/zamg/ @killer0071234
 /homeassistant/components/zengge/ @emontnemery
diff --git a/homeassistant/components/zabbix/__init__.py b/homeassistant/components/zabbix/__init__.py
index d9bab3e6fe4d0..05881d649cf84 100644
--- a/homeassistant/components/zabbix/__init__.py
+++ b/homeassistant/components/zabbix/__init__.py
@@ -11,8 +11,9 @@
 from urllib.error import HTTPError
 from urllib.parse import urljoin
 
-from pyzabbix import ZabbixAPI, ZabbixAPIException, ZabbixMetric, ZabbixSender
 import voluptuous as vol
+from zabbix_utils import ItemValue, Sender, ZabbixAPI
+from zabbix_utils.exceptions import APIRequestError
 
 from homeassistant.const import (
     CONF_HOST,
@@ -42,6 +43,7 @@
 
 DEFAULT_SSL = False
 DEFAULT_PATH = "zabbix"
+DEFAULT_SENDER_PORT = 10051
 
 TIMEOUT = 5
 RETRY_DELAY = 20
@@ -86,7 +88,7 @@ def setup(hass: HomeAssistant, config: ConfigType) -> bool:
     try:
         zapi = ZabbixAPI(url=url, user=username, password=password)
         _LOGGER.debug("Connected to Zabbix API Version %s", zapi.api_version())
-    except ZabbixAPIException as login_exception:
+    except APIRequestError as login_exception:
         _LOGGER.error("Unable to login to the Zabbix API: %s", login_exception)
         return False
     except HTTPError as http_error:
@@ -104,7 +106,7 @@ def setup(hass: HomeAssistant, config: ConfigType) -> bool:
 
     def event_to_metrics(
         event: Event, float_keys: set[str], string_keys: set[str]
-    ) -> list[ZabbixMetric] | None:
+    ) -> list[ItemValue] | None:
         """Add an event to the outgoing Zabbix list."""
         state = event.data.get("new_state")
         if state is None or state.state in (STATE_UNKNOWN, "", STATE_UNAVAILABLE):
@@ -145,14 +147,14 @@ def event_to_metrics(
         float_keys.update(floats)
         if len(float_keys) != float_keys_count:
             floats_discovery = [{"{#KEY}": float_key} for float_key in float_keys]
-            metric = ZabbixMetric(
+            metric = ItemValue(
                 publish_states_host,
                 "homeassistant.floats_discovery",
                 json.dumps(floats_discovery),
             )
             metrics.append(metric)
         for key, value in floats.items():
-            metric = ZabbixMetric(
+            metric = ItemValue(
                 publish_states_host, f"homeassistant.float[{key}]", value
             )
             metrics.append(metric)
@@ -161,7 +163,7 @@ def event_to_metrics(
         return metrics
 
     if publish_states_host:
-        zabbix_sender = ZabbixSender(zabbix_server=conf[CONF_HOST])
+        zabbix_sender = Sender(server=conf[CONF_HOST], port=DEFAULT_SENDER_PORT)
         instance = ZabbixThread(zabbix_sender, event_to_metrics)
         instance.setup(hass)
 
@@ -175,10 +177,8 @@ class ZabbixThread(threading.Thread):
 
     def __init__(
         self,
-        zabbix_sender: ZabbixSender,
-        event_to_metrics: Callable[
-            [Event, set[str], set[str]], list[ZabbixMetric] | None
-        ],
+        zabbix_sender: Sender,
+        event_to_metrics: Callable[[Event, set[str], set[str]], list[ItemValue] | None],
     ) -> None:
         """Initialize the listener."""
         threading.Thread.__init__(self, name="Zabbix")
@@ -208,12 +208,12 @@ def _event_listener(self, event: Event[EventStateChangedData]) -> None:
         item = (time.monotonic(), event)
         self.queue.put(item)
 
-    def get_metrics(self) -> tuple[int, list[ZabbixMetric]]:
+    def get_metrics(self) -> tuple[int, list[ItemValue]]:
         """Return a batch of events formatted for writing."""
         queue_seconds = QUEUE_BACKLOG_SECONDS + self.MAX_TRIES * RETRY_DELAY
 
         count = 0
-        metrics: list[ZabbixMetric] = []
+        metrics: list[ItemValue] = []
 
         dropped = 0
 
@@ -243,7 +243,7 @@ def get_metrics(self) -> tuple[int, list[ZabbixMetric]]:
 
         return count, metrics
 
-    def write_to_zabbix(self, metrics: list[ZabbixMetric]) -> None:
+    def write_to_zabbix(self, metrics: list[ItemValue]) -> None:
         """Write preprocessed events to zabbix, with retry."""
 
         for retry in range(self.MAX_TRIES + 1):
diff --git a/homeassistant/components/zabbix/manifest.json b/homeassistant/components/zabbix/manifest.json
index 9c7171bea4622..86389d2b839c2 100644
--- a/homeassistant/components/zabbix/manifest.json
+++ b/homeassistant/components/zabbix/manifest.json
@@ -1,10 +1,10 @@
 {
   "domain": "zabbix",
   "name": "Zabbix",
-  "codeowners": [],
+  "codeowners": ["@kruton"],
   "documentation": "https://www.home-assistant.io/integrations/zabbix",
   "iot_class": "local_polling",
-  "loggers": ["pyzabbix"],
+  "loggers": ["zabbix_utils"],
   "quality_scale": "legacy",
-  "requirements": ["py-zabbix==1.1.7"]
+  "requirements": ["zabbix-utils==2.0.1"]
 }
diff --git a/homeassistant/components/zabbix/sensor.py b/homeassistant/components/zabbix/sensor.py
index f5d96f106cb17..7728233ebc091 100644
--- a/homeassistant/components/zabbix/sensor.py
+++ b/homeassistant/components/zabbix/sensor.py
@@ -6,8 +6,8 @@
 import logging
 from typing import Any
 
-from pyzabbix import ZabbixAPI
 import voluptuous as vol
+from zabbix_utils import ZabbixAPI
 
 from homeassistant.components.sensor import (
     PLATFORM_SCHEMA as SENSOR_PLATFORM_SCHEMA,
diff --git a/requirements_all.txt b/requirements_all.txt
index a4f61fde79703..dfeb83cc17635 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -1723,9 +1723,6 @@ py-sucks==0.9.10
 # homeassistant.components.synology_dsm
 py-synologydsm-api==2.5.3
 
-# homeassistant.components.zabbix
-py-zabbix==1.1.7
-
 # homeassistant.components.atome
 pyAtome==0.1.1
 
@@ -3084,6 +3081,9 @@ youtubeaio==1.1.5
 # homeassistant.components.media_extractor
 yt-dlp[default]==2024.12.13
 
+# homeassistant.components.zabbix
+zabbix-utils==2.0.1
+
 # homeassistant.components.zamg
 zamg==0.3.6