diff --git a/homeassistant/components/nightscout/sensor.py b/homeassistant/components/nightscout/sensor.py
index 92291bdc4f9957..620349ec3c3ff5 100644
--- a/homeassistant/components/nightscout/sensor.py
+++ b/homeassistant/components/nightscout/sensor.py
@@ -9,9 +9,9 @@
 from aiohttp import ClientError
 from py_nightscout import Api as NightscoutAPI
 
-from homeassistant.components.sensor import SensorEntity
+from homeassistant.components.sensor import SensorDeviceClass, SensorEntity
 from homeassistant.config_entries import ConfigEntry
-from homeassistant.const import ATTR_DATE
+from homeassistant.const import ATTR_DATE, UnitOfBloodGlucoseConcentration
 from homeassistant.core import HomeAssistant
 from homeassistant.helpers.entity_platform import AddEntitiesCallback
 
@@ -37,7 +37,10 @@ async def async_setup_entry(
 class NightscoutSensor(SensorEntity):
     """Implementation of a Nightscout sensor."""
 
-    _attr_native_unit_of_measurement = "mg/dL"
+    _attr_device_class = SensorDeviceClass.BLOOD_GLUCOSE_CONCENTRATION
+    _attr_native_unit_of_measurement = (
+        UnitOfBloodGlucoseConcentration.MILLIGRAMS_PER_DECILITER
+    )
     _attr_icon = "mdi:cloud-question"
 
     def __init__(self, api: NightscoutAPI, name: str, unique_id: str | None) -> None:
diff --git a/homeassistant/components/number/const.py b/homeassistant/components/number/const.py
index 5eea525fb6a579..23e3ce0910bc33 100644
--- a/homeassistant/components/number/const.py
+++ b/homeassistant/components/number/const.py
@@ -17,6 +17,7 @@
     SIGNAL_STRENGTH_DECIBELS,
     SIGNAL_STRENGTH_DECIBELS_MILLIWATT,
     UnitOfApparentPower,
+    UnitOfBloodGlucoseConcentration,
     UnitOfConductivity,
     UnitOfDataRate,
     UnitOfElectricCurrent,
@@ -109,6 +110,12 @@ class NumberDeviceClass(StrEnum):
     Unit of measurement: `%`
     """
 
+    BLOOD_GLUCOSE_CONCENTRATION = "blood_glucose_concentration"
+    """Blood glucose concentration.
+
+    Unit of measurement: `mg/dL`, `mmol/L`
+    """
+
     CO = "carbon_monoxide"
     """Carbon Monoxide gas concentration.
 
@@ -429,6 +436,7 @@ class NumberDeviceClass(StrEnum):
     NumberDeviceClass.AQI: {None},
     NumberDeviceClass.ATMOSPHERIC_PRESSURE: set(UnitOfPressure),
     NumberDeviceClass.BATTERY: {PERCENTAGE},
+    NumberDeviceClass.BLOOD_GLUCOSE_CONCENTRATION: set(UnitOfBloodGlucoseConcentration),
     NumberDeviceClass.CO: {CONCENTRATION_PARTS_PER_MILLION},
     NumberDeviceClass.CO2: {CONCENTRATION_PARTS_PER_MILLION},
     NumberDeviceClass.CONDUCTIVITY: set(UnitOfConductivity),
diff --git a/homeassistant/components/number/icons.json b/homeassistant/components/number/icons.json
index a122aaecb09465..5e0fc6e44d2612 100644
--- a/homeassistant/components/number/icons.json
+++ b/homeassistant/components/number/icons.json
@@ -15,6 +15,9 @@
     "battery": {
       "default": "mdi:battery"
     },
+    "blood_glucose_concentration": {
+      "default": "mdi:spoon-sugar"
+    },
     "carbon_dioxide": {
       "default": "mdi:molecule-co2"
     },
diff --git a/homeassistant/components/number/strings.json b/homeassistant/components/number/strings.json
index 580385172e38a3..b9aec880ecc22f 100644
--- a/homeassistant/components/number/strings.json
+++ b/homeassistant/components/number/strings.json
@@ -43,6 +43,9 @@
     "battery": {
       "name": "[%key:component::sensor::entity_component::battery::name%]"
     },
+    "blood_glucose_concentration": {
+      "name": "[%key:component::sensor::entity_component::blood_glucose_concentration::name%]"
+    },
     "carbon_dioxide": {
       "name": "[%key:component::sensor::entity_component::carbon_dioxide::name%]"
     },
diff --git a/homeassistant/components/recorder/statistics.py b/homeassistant/components/recorder/statistics.py
index 4ffe7c72971d8e..9a66c4542b5e0b 100644
--- a/homeassistant/components/recorder/statistics.py
+++ b/homeassistant/components/recorder/statistics.py
@@ -28,6 +28,7 @@
 from homeassistant.util import dt as dt_util
 from homeassistant.util.unit_conversion import (
     BaseUnitConverter,
+    BloodGlugoseConcentrationConverter,
     ConductivityConverter,
     DataRateConverter,
     DistanceConverter,
@@ -128,6 +129,11 @@
 
 
 STATISTIC_UNIT_TO_UNIT_CONVERTER: dict[str | None, type[BaseUnitConverter]] = {
+    **{
+        unit: BloodGlugoseConcentrationConverter
+        for unit in BloodGlugoseConcentrationConverter.VALID_UNITS
+    },
+    **{unit: ConductivityConverter for unit in ConductivityConverter.VALID_UNITS},
     **{unit: ConductivityConverter for unit in ConductivityConverter.VALID_UNITS},
     **{unit: DataRateConverter for unit in DataRateConverter.VALID_UNITS},
     **{unit: DistanceConverter for unit in DistanceConverter.VALID_UNITS},
diff --git a/homeassistant/components/recorder/websocket_api.py b/homeassistant/components/recorder/websocket_api.py
index ac917e903df25e..8b8d1cfb0c6579 100644
--- a/homeassistant/components/recorder/websocket_api.py
+++ b/homeassistant/components/recorder/websocket_api.py
@@ -16,6 +16,7 @@
 from homeassistant.helpers.json import json_bytes
 from homeassistant.util import dt as dt_util
 from homeassistant.util.unit_conversion import (
+    BloodGlugoseConcentrationConverter,
     ConductivityConverter,
     DataRateConverter,
     DistanceConverter,
@@ -54,6 +55,9 @@
 
 UNIT_SCHEMA = vol.Schema(
     {
+        vol.Optional("blood_glucose_concentration"): vol.In(
+            BloodGlugoseConcentrationConverter.VALID_UNITS
+        ),
         vol.Optional("conductivity"): vol.In(ConductivityConverter.VALID_UNITS),
         vol.Optional("data_rate"): vol.In(DataRateConverter.VALID_UNITS),
         vol.Optional("distance"): vol.In(DistanceConverter.VALID_UNITS),
diff --git a/homeassistant/components/sensor/const.py b/homeassistant/components/sensor/const.py
index aa3d1906b21f73..ee6167a5643368 100644
--- a/homeassistant/components/sensor/const.py
+++ b/homeassistant/components/sensor/const.py
@@ -17,6 +17,7 @@
     SIGNAL_STRENGTH_DECIBELS,
     SIGNAL_STRENGTH_DECIBELS_MILLIWATT,
     UnitOfApparentPower,
+    UnitOfBloodGlucoseConcentration,
     UnitOfConductivity,
     UnitOfDataRate,
     UnitOfElectricCurrent,
@@ -47,6 +48,7 @@
 )
 from homeassistant.util.unit_conversion import (
     BaseUnitConverter,
+    BloodGlugoseConcentrationConverter,
     ConductivityConverter,
     DataRateConverter,
     DistanceConverter,
@@ -127,6 +129,12 @@ class SensorDeviceClass(StrEnum):
     Unit of measurement: `%`
     """
 
+    BLOOD_GLUCOSE_CONCENTRATION = "blood_glucose_concentration"
+    """Blood glucose concentration.
+
+    Unit of measurement: `mg/dL`, `mmol/L`
+    """
+
     CO = "carbon_monoxide"
     """Carbon Monoxide gas concentration.
 
@@ -493,6 +501,7 @@ class SensorStateClass(StrEnum):
 
 UNIT_CONVERTERS: dict[SensorDeviceClass | str | None, type[BaseUnitConverter]] = {
     SensorDeviceClass.ATMOSPHERIC_PRESSURE: PressureConverter,
+    SensorDeviceClass.BLOOD_GLUCOSE_CONCENTRATION: BloodGlugoseConcentrationConverter,
     SensorDeviceClass.CONDUCTIVITY: ConductivityConverter,
     SensorDeviceClass.CURRENT: ElectricCurrentConverter,
     SensorDeviceClass.DATA_RATE: DataRateConverter,
@@ -524,6 +533,7 @@ class SensorStateClass(StrEnum):
     SensorDeviceClass.AQI: {None},
     SensorDeviceClass.ATMOSPHERIC_PRESSURE: set(UnitOfPressure),
     SensorDeviceClass.BATTERY: {PERCENTAGE},
+    SensorDeviceClass.BLOOD_GLUCOSE_CONCENTRATION: set(UnitOfBloodGlucoseConcentration),
     SensorDeviceClass.CO: {CONCENTRATION_PARTS_PER_MILLION},
     SensorDeviceClass.CO2: {CONCENTRATION_PARTS_PER_MILLION},
     SensorDeviceClass.CONDUCTIVITY: set(UnitOfConductivity),
@@ -599,6 +609,7 @@ class SensorStateClass(StrEnum):
     SensorDeviceClass.AQI: {SensorStateClass.MEASUREMENT},
     SensorDeviceClass.ATMOSPHERIC_PRESSURE: {SensorStateClass.MEASUREMENT},
     SensorDeviceClass.BATTERY: {SensorStateClass.MEASUREMENT},
+    SensorDeviceClass.BLOOD_GLUCOSE_CONCENTRATION: {SensorStateClass.MEASUREMENT},
     SensorDeviceClass.CO: {SensorStateClass.MEASUREMENT},
     SensorDeviceClass.CO2: {SensorStateClass.MEASUREMENT},
     SensorDeviceClass.CONDUCTIVITY: {SensorStateClass.MEASUREMENT},
diff --git a/homeassistant/components/sensor/device_condition.py b/homeassistant/components/sensor/device_condition.py
index f2b51899312cda..56ecb36adb3b1d 100644
--- a/homeassistant/components/sensor/device_condition.py
+++ b/homeassistant/components/sensor/device_condition.py
@@ -37,6 +37,7 @@
 CONF_IS_AQI = "is_aqi"
 CONF_IS_ATMOSPHERIC_PRESSURE = "is_atmospheric_pressure"
 CONF_IS_BATTERY_LEVEL = "is_battery_level"
+CONF_IS_BLOOD_GLUCOSE_CONCENTRATION = "is_blood_glucose_concentration"
 CONF_IS_CO = "is_carbon_monoxide"
 CONF_IS_CO2 = "is_carbon_dioxide"
 CONF_IS_CONDUCTIVITY = "is_conductivity"
@@ -87,6 +88,9 @@
     SensorDeviceClass.AQI: [{CONF_TYPE: CONF_IS_AQI}],
     SensorDeviceClass.ATMOSPHERIC_PRESSURE: [{CONF_TYPE: CONF_IS_ATMOSPHERIC_PRESSURE}],
     SensorDeviceClass.BATTERY: [{CONF_TYPE: CONF_IS_BATTERY_LEVEL}],
+    SensorDeviceClass.BLOOD_GLUCOSE_CONCENTRATION: [
+        {CONF_TYPE: CONF_IS_BLOOD_GLUCOSE_CONCENTRATION}
+    ],
     SensorDeviceClass.CO: [{CONF_TYPE: CONF_IS_CO}],
     SensorDeviceClass.CO2: [{CONF_TYPE: CONF_IS_CO2}],
     SensorDeviceClass.CONDUCTIVITY: [{CONF_TYPE: CONF_IS_CONDUCTIVITY}],
@@ -151,6 +155,7 @@
                     CONF_IS_AQI,
                     CONF_IS_ATMOSPHERIC_PRESSURE,
                     CONF_IS_BATTERY_LEVEL,
+                    CONF_IS_BLOOD_GLUCOSE_CONCENTRATION,
                     CONF_IS_CO,
                     CONF_IS_CO2,
                     CONF_IS_CONDUCTIVITY,
diff --git a/homeassistant/components/sensor/device_trigger.py b/homeassistant/components/sensor/device_trigger.py
index b07b3fac11e456..ffee10d9f401b4 100644
--- a/homeassistant/components/sensor/device_trigger.py
+++ b/homeassistant/components/sensor/device_trigger.py
@@ -36,6 +36,7 @@
 CONF_AQI = "aqi"
 CONF_ATMOSPHERIC_PRESSURE = "atmospheric_pressure"
 CONF_BATTERY_LEVEL = "battery_level"
+CONF_BLOOD_GLUCOSE_CONCENTRATION = "blood_glucose_concentration"
 CONF_CO = "carbon_monoxide"
 CONF_CO2 = "carbon_dioxide"
 CONF_CONDUCTIVITY = "conductivity"
@@ -86,6 +87,9 @@
     SensorDeviceClass.AQI: [{CONF_TYPE: CONF_AQI}],
     SensorDeviceClass.ATMOSPHERIC_PRESSURE: [{CONF_TYPE: CONF_ATMOSPHERIC_PRESSURE}],
     SensorDeviceClass.BATTERY: [{CONF_TYPE: CONF_BATTERY_LEVEL}],
+    SensorDeviceClass.BLOOD_GLUCOSE_CONCENTRATION: [
+        {CONF_TYPE: CONF_BLOOD_GLUCOSE_CONCENTRATION}
+    ],
     SensorDeviceClass.CO: [{CONF_TYPE: CONF_CO}],
     SensorDeviceClass.CO2: [{CONF_TYPE: CONF_CO2}],
     SensorDeviceClass.CONDUCTIVITY: [{CONF_TYPE: CONF_CONDUCTIVITY}],
@@ -151,6 +155,7 @@
                     CONF_AQI,
                     CONF_ATMOSPHERIC_PRESSURE,
                     CONF_BATTERY_LEVEL,
+                    CONF_BLOOD_GLUCOSE_CONCENTRATION,
                     CONF_CO,
                     CONF_CO2,
                     CONF_CONDUCTIVITY,
diff --git a/homeassistant/components/sensor/icons.json b/homeassistant/components/sensor/icons.json
index 6132fcbc1e92e4..ea4c902e665735 100644
--- a/homeassistant/components/sensor/icons.json
+++ b/homeassistant/components/sensor/icons.json
@@ -12,6 +12,9 @@
     "atmospheric_pressure": {
       "default": "mdi:thermometer-lines"
     },
+    "blood_glucose_concentration": {
+      "default": "mdi:spoon-sugar"
+    },
     "carbon_dioxide": {
       "default": "mdi:molecule-co2"
     },
diff --git a/homeassistant/components/sensor/strings.json b/homeassistant/components/sensor/strings.json
index 71bead342c40b7..6d529e72c3b2bb 100644
--- a/homeassistant/components/sensor/strings.json
+++ b/homeassistant/components/sensor/strings.json
@@ -6,6 +6,7 @@
       "is_aqi": "Current {entity_name} air quality index",
       "is_atmospheric_pressure": "Current {entity_name} atmospheric pressure",
       "is_battery_level": "Current {entity_name} battery level",
+      "is_blood_glucose_concentration": "Current {entity_name} blood glucose concentration",
       "is_carbon_monoxide": "Current {entity_name} carbon monoxide concentration level",
       "is_carbon_dioxide": "Current {entity_name} carbon dioxide concentration level",
       "is_conductivity": "Current {entity_name} conductivity",
@@ -56,6 +57,7 @@
       "aqi": "{entity_name} air quality index changes",
       "atmospheric_pressure": "{entity_name} atmospheric pressure changes",
       "battery_level": "{entity_name} battery level changes",
+      "blood_glucose_concentration": "{entity_name} blood glucose concentration changes",
       "carbon_monoxide": "{entity_name} carbon monoxide concentration changes",
       "carbon_dioxide": "{entity_name} carbon dioxide concentration changes",
       "conductivity": "{entity_name} conductivity changes",
@@ -149,6 +151,9 @@
     "battery": {
       "name": "Battery"
     },
+    "blood_glucose_concentration": {
+      "name": "Blood glucose concentration"
+    },
     "carbon_monoxide": {
       "name": "Carbon monoxide"
     },
diff --git a/homeassistant/const.py b/homeassistant/const.py
index 0bdd625e417e8b..558e7ec2b0b84e 100644
--- a/homeassistant/const.py
+++ b/homeassistant/const.py
@@ -1358,6 +1358,13 @@ class UnitOfPrecipitationDepth(StrEnum):
 CONCENTRATION_PARTS_PER_BILLION: Final = "ppb"
 
 
+class UnitOfBloodGlucoseConcentration(StrEnum):
+    """Blood glucose concentration units."""
+
+    MILLIGRAMS_PER_DECILITER = "mg/dL"
+    MILLIMOLE_PER_LITER = "mmol/L"
+
+
 # Speed units
 class UnitOfSpeed(StrEnum):
     """Speed units."""
diff --git a/homeassistant/util/unit_conversion.py b/homeassistant/util/unit_conversion.py
index 289df28738ad00..95d8fbc9df1205 100644
--- a/homeassistant/util/unit_conversion.py
+++ b/homeassistant/util/unit_conversion.py
@@ -10,6 +10,7 @@
     CONCENTRATION_PARTS_PER_MILLION,
     PERCENTAGE,
     UNIT_NOT_RECOGNIZED_TEMPLATE,
+    UnitOfBloodGlucoseConcentration,
     UnitOfConductivity,
     UnitOfDataRate,
     UnitOfElectricCurrent,
@@ -173,6 +174,17 @@ class DistanceConverter(BaseUnitConverter):
     }
 
 
+class BloodGlugoseConcentrationConverter(BaseUnitConverter):
+    """Utility to convert blood glucose concentration values."""
+
+    UNIT_CLASS = "blood_glucose_concentration"
+    _UNIT_CONVERSION: dict[str | None, float] = {
+        UnitOfBloodGlucoseConcentration.MILLIGRAMS_PER_DECILITER: 18,
+        UnitOfBloodGlucoseConcentration.MILLIMOLE_PER_LITER: 1,
+    }
+    VALID_UNITS = set(UnitOfBloodGlucoseConcentration)
+
+
 class ConductivityConverter(BaseUnitConverter):
     """Utility to convert electric current values."""
 
diff --git a/tests/util/test_unit_conversion.py b/tests/util/test_unit_conversion.py
index b07b96e0de7db5..a57cdde821fc8e 100644
--- a/tests/util/test_unit_conversion.py
+++ b/tests/util/test_unit_conversion.py
@@ -11,6 +11,7 @@
     CONCENTRATION_PARTS_PER_BILLION,
     CONCENTRATION_PARTS_PER_MILLION,
     PERCENTAGE,
+    UnitOfBloodGlucoseConcentration,
     UnitOfConductivity,
     UnitOfDataRate,
     UnitOfElectricCurrent,
@@ -32,6 +33,7 @@
 from homeassistant.util import unit_conversion
 from homeassistant.util.unit_conversion import (
     BaseUnitConverter,
+    BloodGlugoseConcentrationConverter,
     ConductivityConverter,
     DataRateConverter,
     DistanceConverter,
@@ -59,6 +61,7 @@
 _ALL_CONVERTERS: dict[type[BaseUnitConverter], list[str | None]] = {
     converter: sorted(converter.VALID_UNITS, key=lambda x: (x is None, x))
     for converter in (
+        BloodGlugoseConcentrationConverter,
         ConductivityConverter,
         DataRateConverter,
         DistanceConverter,
@@ -80,6 +83,11 @@
 
 # Dict containing all converters with a corresponding unit ratio.
 _GET_UNIT_RATIO: dict[type[BaseUnitConverter], tuple[str | None, str | None, float]] = {
+    BloodGlugoseConcentrationConverter: (
+        UnitOfBloodGlucoseConcentration.MILLIGRAMS_PER_DECILITER,
+        UnitOfBloodGlucoseConcentration.MILLIMOLE_PER_LITER,
+        18,
+    ),
     ConductivityConverter: (
         UnitOfConductivity.MICROSIEMENS_PER_CM,
         UnitOfConductivity.MILLISIEMENS_PER_CM,
@@ -130,6 +138,20 @@
 _CONVERTED_VALUE: dict[
     type[BaseUnitConverter], list[tuple[float, str | None, float, str | None]]
 ] = {
+    BloodGlugoseConcentrationConverter: [
+        (
+            90,
+            UnitOfBloodGlucoseConcentration.MILLIGRAMS_PER_DECILITER,
+            5,
+            UnitOfBloodGlucoseConcentration.MILLIMOLE_PER_LITER,
+        ),
+        (
+            1,
+            UnitOfBloodGlucoseConcentration.MILLIMOLE_PER_LITER,
+            18,
+            UnitOfBloodGlucoseConcentration.MILLIGRAMS_PER_DECILITER,
+        ),
+    ],
     ConductivityConverter: [
         # Deprecated to deprecated
         (5, UnitOfConductivity.SIEMENS, 5e3, UnitOfConductivity.MILLISIEMENS),