diff --git a/.changelog/4674.txt b/.changelog/4674.txt
new file mode 100644
index 00000000000..c4f4ba1cf2e
--- /dev/null
+++ b/.changelog/4674.txt
@@ -0,0 +1,3 @@
+```release-note:bug
+container: fixed a bug that allowed specifying `node_config` on `google_container_cluster` when autopilot is used
+```
diff --git a/google/resource_container_cluster.go b/google/resource_container_cluster.go
index a81798d6d08..8a68cf701e3 100644
--- a/google/resource_container_cluster.go
+++ b/google/resource_container_cluster.go
@@ -75,6 +75,8 @@ func clusterSchemaNodeConfig() *schema.Schema {
 			changeFieldSchemaToForceNew(sch)
 		}
 	}
+	// Autopilot is only applicable for container cluster
+	nodeConfigSch.ConflictsWith = []string{"enable_autopilot"}
 	return nodeConfigSch
 }