diff --git a/scene/2d/node_2d.cpp b/scene/2d/node_2d.cpp
index 4b7fad5edf06..fb3b19963891 100644
--- a/scene/2d/node_2d.cpp
+++ b/scene/2d/node_2d.cpp
@@ -138,10 +138,6 @@ void Node2D::_update_transform() {
 
 	RenderingServer::get_singleton()->canvas_item_set_transform(get_canvas_item(), transform);
 
-	if (!is_inside_tree()) {
-		return;
-	}
-
 	_notify_transform();
 }
 
@@ -378,10 +374,6 @@ void Node2D::set_transform(const Transform2D &p_transform) {
 
 	RenderingServer::get_singleton()->canvas_item_set_transform(get_canvas_item(), transform);
 
-	if (!is_inside_tree()) {
-		return;
-	}
-
 	_notify_transform();
 }
 
diff --git a/scene/gui/control.cpp b/scene/gui/control.cpp
index 0ca04faf9b1a..63692dd06424 100644
--- a/scene/gui/control.cpp
+++ b/scene/gui/control.cpp
@@ -1734,6 +1734,10 @@ void Control::_size_changed() {
 		if (pos_changed && !size_changed) {
 			_update_canvas_item_transform(); //move because it won't be updated
 		}
+	} else {
+		if (pos_changed) {
+			_notify_transform();
+		}
 	}
 }
 
diff --git a/scene/main/canvas_item.cpp b/scene/main/canvas_item.cpp
index 2947d73552f6..855cad51e9cb 100644
--- a/scene/main/canvas_item.cpp
+++ b/scene/main/canvas_item.cpp
@@ -320,7 +320,6 @@ void CanvasItem::_notification(int p_what) {
 				}
 			}
 
-			_set_global_invalid(true);
 			_enter_canvas();
 
 			RenderingServer::get_singleton()->canvas_item_set_visible(canvas_item, is_visible_in_tree()); // The visibility of the parent may change.
@@ -367,7 +366,11 @@ void CanvasItem::_notification(int p_what) {
 		case NOTIFICATION_WORLD_2D_CHANGED: {
 			_exit_canvas();
 			_enter_canvas();
-		}
+		} break;
+		case NOTIFICATION_PARENTED: {
+			// The node is not inside the tree during this notification.
+			_notify_transform();
+		} break;
 	}
 }
 
diff --git a/scene/main/canvas_item.h b/scene/main/canvas_item.h
index 7f6bbb17c35c..51591e1ac66f 100644
--- a/scene/main/canvas_item.h
+++ b/scene/main/canvas_item.h
@@ -152,11 +152,8 @@ class CanvasItem : public Node {
 
 protected:
 	_FORCE_INLINE_ void _notify_transform() {
-		if (!is_inside_tree()) {
-			return;
-		}
 		_notify_transform(this);
-		if (!block_transform_notify && notify_local_transform) {
+		if (is_inside_tree() && !block_transform_notify && notify_local_transform) {
 			notification(NOTIFICATION_LOCAL_TRANSFORM_CHANGED);
 		}
 	}
diff --git a/tests/scene/test_control.h b/tests/scene/test_control.h
new file mode 100644
index 000000000000..3d7e389e0a70
--- /dev/null
+++ b/tests/scene/test_control.h
@@ -0,0 +1,66 @@
+/**************************************************************************/
+/*  test_control.h                                                        */
+/**************************************************************************/
+/*                         This file is part of:                          */
+/*                             GODOT ENGINE                               */
+/*                        https://godotengine.org                         */
+/**************************************************************************/
+/* Copyright (c) 2014-present Godot Engine contributors (see AUTHORS.md). */
+/* Copyright (c) 2007-2014 Juan Linietsky, Ariel Manzur.                  */
+/*                                                                        */
+/* Permission is hereby granted, free of charge, to any person obtaining  */
+/* a copy of this software and associated documentation files (the        */
+/* "Software"), to deal in the Software without restriction, including    */
+/* without limitation the rights to use, copy, modify, merge, publish,    */
+/* distribute, sublicense, and/or sell copies of the Software, and to     */
+/* permit persons to whom the Software is furnished to do so, subject to  */
+/* the following conditions:                                              */
+/*                                                                        */
+/* The above copyright notice and this permission notice shall be         */
+/* included in all copies or substantial portions of the Software.        */
+/*                                                                        */
+/* THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,        */
+/* EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF     */
+/* MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. */
+/* IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY   */
+/* CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT,   */
+/* TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE      */
+/* SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.                 */
+/**************************************************************************/
+
+#ifndef TEST_CONTROL_H
+#define TEST_CONTROL_H
+
+#include "scene/gui/control.h"
+
+#include "tests/test_macros.h"
+
+namespace TestControl {
+
+TEST_CASE("[SceneTree][Control]") {
+	SUBCASE("[Control][Global Transform] Global Transform should be accessible while not in SceneTree.") { // GH-79453
+		Control *test_node = memnew(Control);
+		Control *test_child = memnew(Control);
+		test_node->add_child(test_child);
+
+		test_node->set_global_position(Point2(1, 1));
+		CHECK_EQ(test_node->get_global_position(), Point2(1, 1));
+		CHECK_EQ(test_child->get_global_position(), Point2(1, 1));
+		test_node->set_global_position(Point2(2, 2));
+		CHECK_EQ(test_node->get_global_position(), Point2(2, 2));
+		test_node->set_scale(Vector2(4, 4));
+		CHECK_EQ(test_node->get_global_transform(), Transform2D(0, Size2(4, 4), 0, Vector2(2, 2)));
+		test_node->set_scale(Vector2(1, 1));
+		test_node->set_rotation_degrees(90);
+		CHECK_EQ(test_node->get_global_transform(), Transform2D(Math_PI / 2, Vector2(2, 2)));
+		test_node->set_pivot_offset(Vector2(1, 0));
+		CHECK_EQ(test_node->get_global_transform(), Transform2D(Math_PI / 2, Vector2(3, 1)));
+
+		memdelete(test_child);
+		memdelete(test_node);
+	}
+}
+
+} // namespace TestControl
+
+#endif // TEST_CONTROL_H
diff --git a/tests/scene/test_node_2d.h b/tests/scene/test_node_2d.h
new file mode 100644
index 000000000000..7e93c77e22f1
--- /dev/null
+++ b/tests/scene/test_node_2d.h
@@ -0,0 +1,63 @@
+/**************************************************************************/
+/*  test_node_2d.h                                                        */
+/**************************************************************************/
+/*                         This file is part of:                          */
+/*                             GODOT ENGINE                               */
+/*                        https://godotengine.org                         */
+/**************************************************************************/
+/* Copyright (c) 2014-present Godot Engine contributors (see AUTHORS.md). */
+/* Copyright (c) 2007-2014 Juan Linietsky, Ariel Manzur.                  */
+/*                                                                        */
+/* Permission is hereby granted, free of charge, to any person obtaining  */
+/* a copy of this software and associated documentation files (the        */
+/* "Software"), to deal in the Software without restriction, including    */
+/* without limitation the rights to use, copy, modify, merge, publish,    */
+/* distribute, sublicense, and/or sell copies of the Software, and to     */
+/* permit persons to whom the Software is furnished to do so, subject to  */
+/* the following conditions:                                              */
+/*                                                                        */
+/* The above copyright notice and this permission notice shall be         */
+/* included in all copies or substantial portions of the Software.        */
+/*                                                                        */
+/* THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,        */
+/* EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF     */
+/* MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. */
+/* IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY   */
+/* CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT,   */
+/* TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE      */
+/* SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.                 */
+/**************************************************************************/
+
+#ifndef TEST_NODE_2D_H
+#define TEST_NODE_2D_H
+
+#include "scene/2d/node_2d.h"
+
+#include "tests/test_macros.h"
+
+namespace TestNode2D {
+
+TEST_CASE("[SceneTree][Node2D]") {
+	SUBCASE("[Node2D][Global Transform] Global Transform should be accessible while not in SceneTree.") { // GH-79453
+		Node2D *test_node = memnew(Node2D);
+		test_node->set_name("node");
+		Node2D *test_child = memnew(Node2D);
+		test_child->set_name("child");
+		test_node->add_child(test_child);
+
+		test_node->set_global_position(Point2(1, 1));
+		CHECK_EQ(test_node->get_global_position(), Point2(1, 1));
+		CHECK_EQ(test_child->get_global_position(), Point2(1, 1));
+		test_node->set_global_position(Point2(2, 2));
+		CHECK_EQ(test_node->get_global_position(), Point2(2, 2));
+		test_node->set_global_transform(Transform2D(0, Point2(3, 3)));
+		CHECK_EQ(test_node->get_global_position(), Point2(3, 3));
+
+		memdelete(test_child);
+		memdelete(test_node);
+	}
+}
+
+} // namespace TestNode2D
+
+#endif // TEST_NODE_2D_H
diff --git a/tests/test_main.cpp b/tests/test_main.cpp
index f42fa517fe7c..6cc7aad48e47 100644
--- a/tests/test_main.cpp
+++ b/tests/test_main.cpp
@@ -95,6 +95,7 @@
 #include "tests/scene/test_bit_map.h"
 #include "tests/scene/test_code_edit.h"
 #include "tests/scene/test_color_picker.h"
+#include "tests/scene/test_control.h"
 #include "tests/scene/test_curve.h"
 #include "tests/scene/test_curve_2d.h"
 #include "tests/scene/test_curve_3d.h"
@@ -106,6 +107,7 @@
 #include "tests/scene/test_navigation_region_2d.h"
 #include "tests/scene/test_navigation_region_3d.h"
 #include "tests/scene/test_node.h"
+#include "tests/scene/test_node_2d.h"
 #include "tests/scene/test_packed_scene.h"
 #include "tests/scene/test_path_2d.h"
 #include "tests/scene/test_path_3d.h"