diff --git a/llvm/lib/Transforms/Scalar/LoopUnrollPass.cpp b/llvm/lib/Transforms/Scalar/LoopUnrollPass.cpp
index b1e06bf1e29316..18007c2bdd4223 100644
--- a/llvm/lib/Transforms/Scalar/LoopUnrollPass.cpp
+++ b/llvm/lib/Transforms/Scalar/LoopUnrollPass.cpp
@@ -1155,9 +1155,11 @@ tryToUnrollLoop(Loop *L, DominatorTree &DT, LoopInfo *LI, ScalarEvolution &SE,
   // automatic unrolling from interfering with the user requested
   // transformation.
   Loop *ParentL = L->getParentLoop();
+  const bool UnrollIsForcedByUser =
+      hasUnrollTransformation(L) == TM_ForcedByUser;
   if (ParentL != nullptr &&
       hasUnrollAndJamTransformation(ParentL) == TM_ForcedByUser &&
-      hasUnrollTransformation(L) != TM_ForcedByUser) {
+      !UnrollIsForcedByUser) {
     LLVM_DEBUG(dbgs() << "Not unrolling loop since parent loop has"
                       << " llvm.loop.unroll_and_jam.\n");
     return LoopUnrollResult::Unmodified;
@@ -1167,7 +1169,7 @@ tryToUnrollLoop(Loop *L, DominatorTree &DT, LoopInfo *LI, ScalarEvolution &SE,
   // loop has an explicit unroll-and-jam pragma. This is to prevent automatic
   // unrolling from interfering with the user requested transformation.
   if (hasUnrollAndJamTransformation(L) == TM_ForcedByUser &&
-      hasUnrollTransformation(L) != TM_ForcedByUser) {
+      !UnrollIsForcedByUser) {
     LLVM_DEBUG(
         dbgs()
         << "  Not unrolling loop since it has llvm.loop.unroll_and_jam.\n");
@@ -1217,7 +1219,11 @@ tryToUnrollLoop(Loop *L, DominatorTree &DT, LoopInfo *LI, ScalarEvolution &SE,
   if (OptForSize)
     UP.Threshold = std::max(UP.Threshold, LoopSize + 1);
 
-  if (UCE.NumInlineCandidates != 0) {
+  // Ignore the potential for inlining if unrolling is forced by the user. It's
+  // only _very likely_ that `NumInlineCandidates` functions will be inlined;
+  // things like profile data can make this significantly less likely.
+  if ((PrepareForLTO || !UnrollIsForcedByUser) &&
+      UCE.NumInlineCandidates != 0) {
     LLVM_DEBUG(dbgs() << "  Not unrolling loop with inlinable calls.\n");
     return LoopUnrollResult::Unmodified;
   }
diff --git a/llvm/test/Transforms/LoopUnroll/unroll-calls-if-forced.ll b/llvm/test/Transforms/LoopUnroll/unroll-calls-if-forced.ll
new file mode 100644
index 00000000000000..00b774ea898d5c
--- /dev/null
+++ b/llvm/test/Transforms/LoopUnroll/unroll-calls-if-forced.ll
@@ -0,0 +1,35 @@
+; RUN: opt -passes=loop-unroll -S < %s | FileCheck %s
+;
+; Ensure that loop unrolling occurs if the user forces it, even if there are
+; calls that may be inlined.
+
+target datalayout = "e-m:e-i64:64-f80:128-n8:16:32:64-S128"
+
+define internal void @foo() {
+  ret void
+}
+
+; CHECK-LABEL: @forced(
+; CHECK: call {{.*}}void @foo
+; CHECK: call {{.*}}void @foo
+define void @forced(ptr nocapture %a) {
+entry:
+  br label %for.body
+
+for.body:
+  %indvars.iv = phi i64 [ 0, %entry ], [ %indvars.iv.next, %for.body ]
+  %arrayidx = getelementptr inbounds i32, ptr %a, i64 %indvars.iv
+  call void @foo()
+  %0 = load i32, ptr %arrayidx, align 4
+  %inc = add nsw i32 %0, 1
+  store i32 %inc, ptr %arrayidx, align 4
+  %indvars.iv.next = add nuw nsw i64 %indvars.iv, 1
+  %exitcond = icmp eq i64 %indvars.iv.next, 64
+  br i1 %exitcond, label %for.end, label %for.body, !llvm.loop !0
+
+for.end:
+  ret void
+}
+
+!0 = distinct !{!0, !{!"llvm.loop.unroll.enable"},
+                    !{!"llvm.loop.unroll.count", i32 2}}