diff --git a/tools/buildtools/ambertools/acpype.xml b/tools/buildtools/ambertools/acpype.xml
index 8b7d87ef..886cdfd9 100644
--- a/tools/buildtools/ambertools/acpype.xml
+++ b/tools/buildtools/ambertools/acpype.xml
@@ -5,7 +5,7 @@
         <token name="@GALAXY_VERSION@">0</token>
     </macros>
     <expand macro="requirements">
-        <requirement type="package" version="2021.02.05.22.15">acpype</requirement>
+        <requirement type="package" version="2022.1.3">acpype</requirement>
     </expand>
     <command detect_errors="exit_code"><![CDATA[
         ln -s '$input1' ./input1.${input1.ext} &&
diff --git a/tools/buildtools/ambertools/macros.xml b/tools/buildtools/ambertools/macros.xml
index 3b7839b6..34a1f4f6 100644
--- a/tools/buildtools/ambertools/macros.xml
+++ b/tools/buildtools/ambertools/macros.xml
@@ -1,5 +1,5 @@
 <macros>
-  <token name="@TOOL_VERSION@">21.11</token>
+  <token name="@TOOL_VERSION@">21.12</token>
   <xml name="requirements">
     <requirements>
       <requirement type="package" version="@TOOL_VERSION@">ambertools</requirement>
diff --git a/tools/buildtools/ambertools/mmpbsa_mmgbsa.xml b/tools/buildtools/ambertools/mmpbsa_mmgbsa.xml
index cb9e9059..4765e641 100644
--- a/tools/buildtools/ambertools/mmpbsa_mmgbsa.xml
+++ b/tools/buildtools/ambertools/mmpbsa_mmgbsa.xml
@@ -5,7 +5,7 @@
         <token name="@GALAXY_VERSION@">0</token>
     </macros>
     <expand macro="requirements">
-        <requirement type="package" version="3.0.2">jinja2</requirement>
+        <requirement type="package" version="3.0.3">jinja2</requirement>
     </expand>
     <command detect_errors="exit_code"><![CDATA[
         python '$mmpbsa_script' '$inputs' &&
diff --git a/tools/buildtools/ambertools/parmconv.xml b/tools/buildtools/ambertools/parmconv.xml
index 9b7e01ac..8434f9b9 100644
--- a/tools/buildtools/ambertools/parmconv.xml
+++ b/tools/buildtools/ambertools/parmconv.xml
@@ -7,7 +7,7 @@
   <expand macro="requirements">
     <requirement type="package" version="3.4.3">parmed</requirement>
     <requirement type="package" version="2021.3">gromacs</requirement>
-    <requirement type="package" version="3.0.2">jinja2</requirement>
+    <requirement type="package" version="3.0.3">jinja2</requirement>
   </expand>
   <command detect_errors="exit_code">
     <![CDATA[