diff --git a/asv_bench/benchmarks/pandas_vb_common.py b/asv_bench/benchmarks/pandas_vb_common.py
index b1a58e49fe86c4..03d3b56b737fbe 100644
--- a/asv_bench/benchmarks/pandas_vb_common.py
+++ b/asv_bench/benchmarks/pandas_vb_common.py
@@ -23,11 +23,6 @@
     except:
         pass
 
-try:
-    Panel = Panel
-except Exception:
-    Panel = WidePanel
-
 # didn't add to namespace until later
 try:
     from pandas.core.index import MultiIndex
diff --git a/doc/source/whatsnew/v0.22.0.txt b/doc/source/whatsnew/v0.22.0.txt
index 2c0ccd377492a9..aeae9b3325f6ed 100644
--- a/doc/source/whatsnew/v0.22.0.txt
+++ b/doc/source/whatsnew/v0.22.0.txt
@@ -65,6 +65,7 @@ Removal of prior version deprecations/changes
 
 - Warnings against the obsolete usage ``Categorical(codes, categories)``, which were emitted for instance when the first two arguments to ``Categorical()`` had different dtypes, and recommended the use of ``Categorical.from_codes``, have now been removed (:issue:`8074`)
 - The ``levels`` and ``labels`` attributes of a ``MultiIndex`` can no longer be set directly (:issue:`4039`).
+- The ``LongPanel`` and ``WidePanel`` classes have been removed (:issue:`10892`)
 -
 
 .. _whatsnew_0220.performance:
diff --git a/pandas/core/api.py b/pandas/core/api.py
index 1f46aaa40e9eb9..a3d86ed1e9e3c8 100644
--- a/pandas/core/api.py
+++ b/pandas/core/api.py
@@ -21,7 +21,7 @@
 
 from pandas.core.series import Series
 from pandas.core.frame import DataFrame
-from pandas.core.panel import Panel, WidePanel
+from pandas.core.panel import Panel
 from pandas.core.panel4d import Panel4D
 from pandas.core.reshape.reshape import (
     pivot_simple as pivot, get_dummies)
diff --git a/pandas/core/panel.py b/pandas/core/panel.py
index 327180b6a6e84d..6f06c779f21ec8 100644
--- a/pandas/core/panel.py
+++ b/pandas/core/panel.py
@@ -1617,24 +1617,3 @@ def f(self, other, axis=0):
 ops.add_special_arithmetic_methods(Panel, **ops.panel_special_funcs)
 Panel._add_aggregate_operations()
 Panel._add_numeric_operations()
-
-
-# legacy
-class WidePanel(Panel):
-
-    def __init__(self, *args, **kwargs):
-        # deprecation, #10892
-        warnings.warn("WidePanel is deprecated. Please use Panel",
-                      FutureWarning, stacklevel=2)
-
-        super(WidePanel, self).__init__(*args, **kwargs)
-
-
-class LongPanel(DataFrame):
-
-    def __init__(self, *args, **kwargs):
-        # deprecation, #10892
-        warnings.warn("LongPanel is deprecated. Please use DataFrame",
-                      FutureWarning, stacklevel=2)
-
-        super(LongPanel, self).__init__(*args, **kwargs)
diff --git a/pandas/tests/api/test_api.py b/pandas/tests/api/test_api.py
index fad455d6391c33..2b72bf5460c62f 100644
--- a/pandas/tests/api/test_api.py
+++ b/pandas/tests/api/test_api.py
@@ -51,7 +51,7 @@ class TestPDApi(Base):
                'TimedeltaIndex', 'Timestamp', 'Interval', 'IntervalIndex']
 
     # these are already deprecated; awaiting removal
-    deprecated_classes = ['WidePanel', 'Panel4D', 'TimeGrouper',
+    deprecated_classes = ['Panel4D', 'TimeGrouper',
                           'SparseList', 'Expr', 'Term']
 
     # these should be deprecated in the future
diff --git a/pandas/tests/io/test_pytables.py b/pandas/tests/io/test_pytables.py
index 13bf81889af1a6..a7598c2dc305ad 100644
--- a/pandas/tests/io/test_pytables.py
+++ b/pandas/tests/io/test_pytables.py
@@ -3145,9 +3145,6 @@ def _check(left, right):
             wp = tm.makePanel()
             self._check_roundtrip(wp.to_frame(), _check)
 
-    def test_longpanel(self):
-        pass
-
     def test_overwrite_node(self):
 
         with ensure_clean_store(self.path) as store:
diff --git a/pandas/tests/test_panel.py b/pandas/tests/test_panel.py
index 42df2e26b301fc..fd83a36a7f3274 100644
--- a/pandas/tests/test_panel.py
+++ b/pandas/tests/test_panel.py
@@ -184,10 +184,6 @@ def wrapper(x):
 
 class SafeForSparse(object):
 
-    @classmethod
-    def assert_panel_equal(cls, x, y):
-        assert_panel_equal(x, y)
-
     def test_get_axis(self):
         assert (self.panel._get_axis(0) is self.panel.items)
         assert (self.panel._get_axis(1) is self.panel.major_axis)
@@ -358,8 +354,7 @@ def test_combinePanel(self):
             assert_panel_equal(result, self.panel * 2)
 
     def test_neg(self):
-        with catch_warnings(record=True):
-            assert_panel_equal(-self.panel, self.panel * -1)
+        assert_panel_equal(-self.panel, self.panel * -1)
 
     # issue 7692
     def test_raise_when_not_implemented(self):
@@ -906,10 +901,6 @@ def test_set_value(self):
 class TestPanel(PanelTests, CheckIndexing, SafeForLongAndSparse,
                 SafeForSparse):
 
-    @classmethod
-    def assert_panel_equal(cls, x, y):
-        assert_panel_equal(x, y)
-
     def setup_method(self, method):
         self.panel = make_test_panel()
         self.panel.major_axis.name = None
@@ -2155,8 +2146,8 @@ def test_multiindex_get(self):
             assert (f1.items == [1, 2]).all()
             assert (f2.items == [1, 2]).all()
 
-            ind = MultiIndex.from_tuples([('a', 1), ('a', 2), ('b', 1)],
-                                         names=['first', 'second'])
+            MultiIndex.from_tuples([('a', 1), ('a', 2), ('b', 1)],
+                                   names=['first', 'second'])
 
     def test_multiindex_blocks(self):
         with catch_warnings(record=True):
@@ -2461,13 +2452,14 @@ def test_sort_values(self):
         pytest.raises(NotImplementedError, self.panel.sort_values, 'ItemA')
 
 
-class TestLongPanel(object):
+class TestPanelFrame(object):
     """
-    LongPanel no longer exists, but...
+    Check that conversions to and from Panel to DataFrame work.
     """
 
-    def setup_method(self, method):
+    def setUp(self):
         panel = make_test_panel()
+
         self.panel = panel.to_frame()
         self.unfiltered_panel = panel.to_frame(filter_observations=False)