diff --git a/plugins/flytekit-vaex/setup.py b/plugins/flytekit-vaex/setup.py
index 57cf07df68..c3b442b77e 100644
--- a/plugins/flytekit-vaex/setup.py
+++ b/plugins/flytekit-vaex/setup.py
@@ -4,7 +4,11 @@
 
 microlib_name = f"flytekitplugins-{PLUGIN_NAME}"
 
-plugin_requires = ["flytekit>=1.3.0b2,<2.0.0", "vaex-core>=4.13.0,<4.14"]
+plugin_requires = [
+    "flytekit>=1.3.0b2,<2.0.0",
+    "vaex-core>=4.13.0,<4.14; python_version < '3.10'",
+    "vaex-core>=4.16.0; python_version >= '3.10'",
+]
 
 __version__ = "0.0.0+develop"