diff --git a/.github/workflows/pythonbuild.yml b/.github/workflows/pythonbuild.yml
index bcf1bc2636..aaec09a75d 100644
--- a/.github/workflows/pythonbuild.yml
+++ b/.github/workflows/pythonbuild.yml
@@ -15,7 +15,7 @@ jobs:
     strategy:
       fail-fast: false
       matrix:
-        os: [ubuntu-latest, windows-latest]
+        os: [ubuntu-latest, windows-latest, macos-latest]
         python-version: ["3.8", "3.9", "3.10", "3.11"]
         exclude:
           # Ignore this test because we failed to install docker-py
diff --git a/tests/flytekit/unit/cli/pyflyte/test_run.py b/tests/flytekit/unit/cli/pyflyte/test_run.py
index 1daaba5b5f..f7cf2f4662 100644
--- a/tests/flytekit/unit/cli/pyflyte/test_run.py
+++ b/tests/flytekit/unit/cli/pyflyte/test_run.py
@@ -2,6 +2,7 @@
 import json
 import os
 import pathlib
+import sys
 import tempfile
 import typing
 from datetime import datetime, timedelta
@@ -295,6 +296,10 @@ def test_list_default_arguments(wf_path):
         (IMAGE_SPEC, "sample.yaml", ic_result_4),
     ],
 )
+@pytest.mark.skipif(
+    os.environ["GITHUB_ACTIONS"] == "true" and sys.platform == "darwin",
+    reason="Github macos-latest image does not have docker installed as per https://github.com/orgs/community/discussions/25777",
+)
 def test_pyflyte_run_run(mock_image, image_string, leaf_configuration_file_name, final_image_config):
     mock_image.return_value = "cr.flyte.org/flyteorg/flytekit:py3.9-latest"