diff --git a/flytekit/core/array_node_map_task.py b/flytekit/core/array_node_map_task.py
index e621a786b4..a3455a9fb1 100644
--- a/flytekit/core/array_node_map_task.py
+++ b/flytekit/core/array_node_map_task.py
@@ -23,6 +23,7 @@
 from flytekit.models.interface import Variable
 from flytekit.models.task import Container, K8sPod, Sql, Task
 from flytekit.tools.module_loader import load_object_from_module
+from flytekit.types.pickle.pickle import FlytePickleTransformer
 
 
 class ArrayNodeMapTask(PythonTask):
@@ -55,6 +56,11 @@ def __init__(
         else:
             actual_task = python_function_task
 
+        for _, v in actual_task.python_interface.inputs.items():
+            transformer = TypeEngine.get_transformer(v)
+            if isinstance(transformer, FlytePickleTransformer):
+                raise ValueError("Pickle transformers are not supported in map tasks.")
+
         # TODO: add support for other Flyte entities
         if not (isinstance(actual_task, PythonFunctionTask) or isinstance(actual_task, PythonInstanceTask)):
             raise ValueError("Only PythonFunctionTask and PythonInstanceTask are supported in map tasks.")
@@ -224,6 +230,7 @@ def _literal_map_to_python_input(
             inputs_interface = self._run_task.python_interface.inputs
             for k in self.interface.inputs.keys():
                 v = literal_map.literals[k]
+
                 if k not in self.bound_inputs:
                     # assert that v.collection is not None
                     if not v.collection or not isinstance(v.collection.literals, list):
diff --git a/tests/flytekit/unit/core/test_array_node_map_task.py b/tests/flytekit/unit/core/test_array_node_map_task.py
index 9a994d8eee..ff428b5c6d 100644
--- a/tests/flytekit/unit/core/test_array_node_map_task.py
+++ b/tests/flytekit/unit/core/test_array_node_map_task.py
@@ -74,6 +74,15 @@ def say_hello(name: str) -> str:
         assert res.literals["o0"].scalar.primitive.string_value == "hello earth!"
 
 
+def test_map_task_with_pickle():
+    @task
+    def say_hello(name: typing.Any) -> str:
+        return f"hello {name}!"
+
+    with pytest.raises(ValueError, match="Pickle transformers are not supported in map tasks"):
+        map_task(say_hello)(name=["abc", "def"])
+
+
 def test_serialization(serialization_settings):
     @task
     def t1(a: int) -> int: