diff --git a/README.md b/README.md
index f9adbd7..439a3c4 100644
--- a/README.md
+++ b/README.md
@@ -113,6 +113,26 @@ fastify.register(async function (fastify) {
 fastify.listen({ port: 3000 })
 ```
 
+### Disabling CORS for a specific route
+
+CORS can be disabled at the route level by setting the `cors` option to `false`.
+
+```js
+const fastify = require('fastify')()
+
+fastify.register(require('@fastify/cors'), { origin: '*' })
+
+fastify.get('/cors-enabled', (_req, reply) => {
+  reply.send('CORS headers')
+})
+
+fastify.get('/cors-disabled', { cors: false }, (_req, reply) => {
+  reply.send('No CORS headers')
+})
+
+fastify.listen({ port: 3000 })
+```
+
 ### Custom Fastify hook name
 
 By default, `@fastify/cors` adds a `onRequest` hook where the validation and header injection are executed. This can be customized by passing `hook` in the options. Valid values are `onRequest`, `preParsing`, `preValidation`, `preHandler`, `preSerialization`, and `onSend`.
diff --git a/index.js b/index.js
index 2ed7590..2edba47 100644
--- a/index.js
+++ b/index.js
@@ -171,6 +171,11 @@ function addCorsHeadersHandler (fastify, options, req, reply, next) {
       return next()
     }
 
+    // Allow routes to disable CORS individually
+    if (req.routeOptions.config?.cors === false) {
+      return next()
+    }
+
     // Falsy values are invalid
     if (!resolvedOriginOption) {
       return next(new Error('Invalid CORS origin option'))
diff --git a/test/cors.test.js b/test/cors.test.js
index 9aacaa9..10aebc2 100644
--- a/test/cors.test.js
+++ b/test/cors.test.js
@@ -1015,3 +1015,38 @@ test('Should support wildcard config /2', async t => {
   t.assert.strictEqual(res.payload, 'ok')
   t.assert.strictEqual(res.headers['access-control-allow-origin'], '*')
 })
+
+test('Should allow routes to disable CORS individually', async t => {
+  t.plan(6)
+
+  const fastify = Fastify()
+  fastify.register(cors, { origin: '*' })
+
+  fastify.get('/cors-enabled', (_req, reply) => {
+    reply.send('ok')
+  })
+
+  fastify.get('/cors-disabled', { config: { cors: false } }, (_req, reply) => {
+    reply.send('ok')
+  })
+
+  // Test CORS enabled route
+  let res = await fastify.inject({
+    method: 'GET',
+    url: '/cors-enabled',
+    headers: { origin: 'example.com' }
+  })
+  t.assert.ok(res)
+  t.assert.strictEqual(res.statusCode, 200)
+  t.assert.strictEqual(res.headers['access-control-allow-origin'], '*')
+
+  // Test CORS disabled route
+  res = await fastify.inject({
+    method: 'GET',
+    url: '/cors-disabled',
+    headers: { origin: 'example.com' }
+  })
+  t.assert.ok(res)
+  t.assert.strictEqual(res.statusCode, 200)
+  t.assert.strictEqual(res.headers['access-control-allow-origin'], undefined)
+})