diff --git a/x-pack/plugins/security_solution/public/management/cypress/e2e/automated_response_actions/automated_response_actions.cy.ts b/x-pack/plugins/security_solution/public/management/cypress/e2e/automated_response_actions/automated_response_actions.cy.ts
index 4c6b2ceec4e5e..20bfa44d0f8f9 100644
--- a/x-pack/plugins/security_solution/public/management/cypress/e2e/automated_response_actions/automated_response_actions.cy.ts
+++ b/x-pack/plugins/security_solution/public/management/cypress/e2e/automated_response_actions/automated_response_actions.cy.ts
@@ -20,8 +20,7 @@ import { createEndpointHost } from '../../tasks/create_endpoint_host';
 import { deleteAllLoadedEndpointData } from '../../tasks/delete_all_endpoint_data';
 import { enableAllPolicyProtections } from '../../tasks/endpoint_policy';
 
-// Failing: See https://github.com/elastic/kibana/issues/168427
-describe.skip(
+describe(
   'Automated Response Actions',
   {
     tags: ['@ess', '@serverless'],
@@ -74,8 +73,7 @@ describe.skip(
       login();
     });
 
-    // FLAKY: https://github.com/elastic/kibana/issues/168340
-    describe.skip('From alerts', () => {
+    describe('From alerts', () => {
       let ruleId: string;
       let ruleName: string;
 
diff --git a/x-pack/plugins/security_solution/public/management/cypress/e2e/endpoint_list/endpoints.cy.ts b/x-pack/plugins/security_solution/public/management/cypress/e2e/endpoint_list/endpoints.cy.ts
index e1a291cc19a25..217b13f96f934 100644
--- a/x-pack/plugins/security_solution/public/management/cypress/e2e/endpoint_list/endpoints.cy.ts
+++ b/x-pack/plugins/security_solution/public/management/cypress/e2e/endpoint_list/endpoints.cy.ts
@@ -28,9 +28,7 @@ import { createEndpointHost } from '../../tasks/create_endpoint_host';
 import { deleteAllLoadedEndpointData } from '../../tasks/delete_all_endpoint_data';
 import { enableAllPolicyProtections } from '../../tasks/endpoint_policy';
 
-// Failing: See https://github.com/elastic/kibana/issues/168719
-// FLAKY: https://github.com/elastic/kibana/issues/168284
-describe.skip('Endpoints page', { tags: ['@ess', '@serverless'] }, () => {
+describe('Endpoints page', { tags: ['@ess', '@serverless'] }, () => {
   let indexedPolicy: IndexedFleetEndpointPolicyResponse;
   let policy: PolicyData;
   let createdHost: CreateAndEnrollEndpointHostResponse;
diff --git a/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/execute.cy.ts b/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/execute.cy.ts
index b574ca98d5f44..042031b301185 100644
--- a/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/execute.cy.ts
+++ b/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/execute.cy.ts
@@ -21,14 +21,12 @@ import { enableAllPolicyProtections } from '../../../tasks/endpoint_policy';
 import { createEndpointHost } from '../../../tasks/create_endpoint_host';
 import { deleteAllLoadedEndpointData } from '../../../tasks/delete_all_endpoint_data';
 
-// Failing: See https://github.com/elastic/kibana/issues/171444
-describe.skip('Response console', { tags: ['@ess', '@serverless'] }, () => {
+describe('Response console', { tags: ['@ess', '@serverless'] }, () => {
   beforeEach(() => {
     login();
   });
 
-  // FLAKY: https://github.com/elastic/kibana/issues/170373
-  describe.skip('Execute operations:', () => {
+  describe('Execute operations:', () => {
     const homeFilePath = process.env.CI || true ? '/home/vagrant' : `/home/ubuntu`;
 
     let indexedPolicy: IndexedFleetEndpointPolicyResponse;
diff --git a/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/isolate.cy.ts b/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/isolate.cy.ts
index da54bc85acb68..f89f2a6f62ecf 100644
--- a/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/isolate.cy.ts
+++ b/x-pack/plugins/security_solution/public/management/cypress/e2e/response_actions/response_console/isolate.cy.ts
@@ -26,8 +26,7 @@ import { enableAllPolicyProtections } from '../../../tasks/endpoint_policy';
 import { createEndpointHost } from '../../../tasks/create_endpoint_host';
 import { deleteAllLoadedEndpointData } from '../../../tasks/delete_all_endpoint_data';
 
-// Failing: See https://github.com/elastic/kibana/issues/173465
-describe.skip('Response console', { tags: ['@ess', '@serverless'] }, () => {
+describe('Response console', { tags: ['@ess', '@serverless'] }, () => {
   let indexedPolicy: IndexedFleetEndpointPolicyResponse;
   let policy: PolicyData;
   let createdHost: CreateAndEnrollEndpointHostResponse;
@@ -62,8 +61,7 @@ describe.skip('Response console', { tags: ['@ess', '@serverless'] }, () => {
     }
   });
 
-  // FLAKY: https://github.com/elastic/kibana/issues/173464
-  describe.skip('Host Isolation:', () => {
+  describe('Host Isolation:', () => {
     beforeEach(() => {
       login();
     });