diff --git a/docs/changelog/96494.yaml b/docs/changelog/96494.yaml
new file mode 100644
index 0000000000000..9f2b58c5b4044
--- /dev/null
+++ b/docs/changelog/96494.yaml
@@ -0,0 +1,6 @@
+pr: 96494
+summary: Do not copy `index.default_pipeline` and `index.final_pipeline`
+area: Rollup
+type: bug
+issues:
+ - 96478
diff --git a/x-pack/plugin/rollup/qa/rest/build.gradle b/x-pack/plugin/rollup/qa/rest/build.gradle
index e91e56d2d1ba4..1cffa7fcafc6a 100644
--- a/x-pack/plugin/rollup/qa/rest/build.gradle
+++ b/x-pack/plugin/rollup/qa/rest/build.gradle
@@ -17,7 +17,7 @@ dependencies {
 
 restResources {
   restApi {
-    include '_common', 'bulk', 'cluster', 'indices', 'search'
+    include '_common', 'bulk', 'cluster', 'indices', 'search', 'ingest.put_pipeline', 'ingest.delete_pipeline'
   }
 }
 
diff --git a/x-pack/plugin/rollup/qa/rest/src/yamlRestTest/resources/rest-api-spec/test/rollup/60_settings.yml b/x-pack/plugin/rollup/qa/rest/src/yamlRestTest/resources/rest-api-spec/test/rollup/60_settings.yml
new file mode 100644
index 0000000000000..7b1b6d6a2134b
--- /dev/null
+++ b/x-pack/plugin/rollup/qa/rest/src/yamlRestTest/resources/rest-api-spec/test/rollup/60_settings.yml
@@ -0,0 +1,100 @@
+---
+"Downsample index with pipeline":
+  - skip:
+      version: " - 8.4.99"
+      reason: "rollup renamed to downsample in 8.5.0"
+
+  - do:
+      ingest.put_pipeline:
+        id: "pipeline"
+        body: >
+          {
+            "processors": [
+             {
+               "set" : {
+                 "field" : "field",
+                 "value": 42
+               }
+              }
+            ]
+          }
+
+  - do:
+      indices.create:
+        index: test
+        body:
+          settings:
+            number_of_shards: 1
+            number_of_replicas: 0
+            index:
+              default_pipeline: "pipeline"
+              final_pipeline: "pipeline"
+              mode: time_series
+              routing_path: [metricset, k8s.pod.uid]
+              time_series:
+                start_time: 2021-04-28T00:00:00Z
+                end_time: 2021-04-29T00:00:00Z
+          mappings:
+            properties:
+              "@timestamp":
+                type: date
+              metricset:
+                type: keyword
+                time_series_dimension: true
+              value:
+                type: double
+                time_series_metric: gauge
+  - do:
+      bulk:
+        refresh: true
+        index: test
+        body:
+          - '{"index": {}}'
+          - '{"@timestamp": "2021-04-28T18:50:04.467Z", "metricset": "pod", "value": 10}'
+
+  - do:
+      search:
+        index: test
+        body:
+          query:
+            match_all: {}
+
+  - match: { hits.total.value: 1 }
+  - match: { hits.hits.0._source.field: 42 }
+
+  - do:
+      indices.put_settings:
+        index: test
+        body:
+          index.blocks.write: true
+
+  - do:
+      indices.downsample:
+        index: test
+        target_index: test-rollup
+        body: >
+          {
+            "fixed_interval": "1h"
+          }
+
+  - do:
+      indices.get_settings:
+        index: test
+
+  - match: { test.settings.index.default_pipeline: "pipeline" }
+  - match: { test.settings.index.final_pipeline: "pipeline" }
+
+  - do:
+      indices.get_settings:
+        index: test-rollup
+
+  - match: { test-rollup.settings.index.default_pipeline: null }
+  - match: { test-rollup.settings.index.final_pipeline: null }
+
+
+---
+teardown:
+  - do:
+      ingest.delete_pipeline:
+        id: "pipeline"
+        ignore: 404
diff --git a/x-pack/plugin/rollup/src/main/java/org/elasticsearch/xpack/downsample/TransportDownsampleAction.java b/x-pack/plugin/rollup/src/main/java/org/elasticsearch/xpack/downsample/TransportDownsampleAction.java
index 3f71701d3ae17..d175f41b561ef 100644
--- a/x-pack/plugin/rollup/src/main/java/org/elasticsearch/xpack/downsample/TransportDownsampleAction.java
+++ b/x-pack/plugin/rollup/src/main/java/org/elasticsearch/xpack/downsample/TransportDownsampleAction.java
@@ -76,6 +76,7 @@
 import java.util.ArrayList;
 import java.util.List;
 import java.util.Map;
+import java.util.Set;
 
 import static org.elasticsearch.index.mapper.TimeSeriesParams.TIME_SERIES_METRIC_PARAM;
 
@@ -97,6 +98,12 @@ public class TransportDownsampleAction extends AcknowledgedTransportMasterNodeAc
     private final IndexScopedSettings indexScopedSettings;
     private final ThreadContext threadContext;
 
+    private static final Set<String> FORBIDDEN_SETTINGS = Set.of(
+        IndexSettings.DEFAULT_PIPELINE.getKey(),
+        IndexSettings.FINAL_PIPELINE.getKey(),
+        IndexMetadata.INDEX_BLOCKS_WRITE_SETTING.getKey()
+    );
+
     /**
      * This is the cluster state task executor for cluster state update actions.
      */
@@ -584,12 +591,15 @@ private IndexMetadata.Builder copyIndexMetadata(IndexMetadata sourceIndexMetadat
                 // the same rules with resize apply
                 continue;
             }
+            // Do not copy index settings which are valid for the source index but not for the target index
+            if (FORBIDDEN_SETTINGS.contains(key)) {
+                continue;
+            }
             // Do not override settings that have already been set in the rollup index.
-            // Also, we don't want to copy the `index.block.write` setting that we know
-            // it is set in the source index settings.
-            if (IndexMetadata.SETTING_BLOCKS_WRITE.equals(key) || targetSettings.keys().contains(key)) {
+            if (targetSettings.keys().contains(key)) {
                 continue;
             }
+
             targetSettings.copy(key, sourceIndexMetadata.getSettings());
         }