diff --git a/detectors/node/opentelemetry-resource-detector-github/package.json b/detectors/node/opentelemetry-resource-detector-github/package.json
index c17137b53a7..e5c3c468c56 100644
--- a/detectors/node/opentelemetry-resource-detector-github/package.json
+++ b/detectors/node/opentelemetry-resource-detector-github/package.json
@@ -49,12 +49,10 @@
     "codecov": "3.7.2",
     "gts": "3.1.0",
     "mocha": "7.2.0",
-    "nock": "13.0.5",
     "nyc": "15.1.0",
     "rimraf": "3.0.2",
     "sinon": "10.0.0",
     "ts-mocha": "8.0.0",
-    "ts-node": "8.10.2",
     "typescript": "4.1.3"
   },
   "dependencies": {
diff --git a/examples/graphql/package.json b/examples/graphql/package.json
index d1137117f20..be188f01cf0 100644
--- a/examples/graphql/package.json
+++ b/examples/graphql/package.json
@@ -31,7 +31,6 @@
     "url": "https://github.com/open-telemetry/opentelemetry-js/issues"
   },
   "dependencies": {
-    "@opentelemetry/api": "^1.0.0-rc.0",
     "@opentelemetry/exporter-collector": "^0.19.0",
     "@opentelemetry/instrumentation": "^0.19.0",
     "@opentelemetry/instrumentation-graphql": "^0.15.0",
@@ -42,8 +41,7 @@
     "apollo-server": "^2.18.1",
     "express": "^4.17.1",
     "express-graphql": "^0.11.0",
-    "graphql": "^15.3.0",
-    "qs-middleware": "^1.0.3"
+    "graphql": "^15.3.0"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js#readme",
   "devDependencies": {
diff --git a/examples/grpc-census-prop/package.json b/examples/grpc-census-prop/package.json
index 9eec5cceaf0..6edf56770be 100644
--- a/examples/grpc-census-prop/package.json
+++ b/examples/grpc-census-prop/package.json
@@ -41,8 +41,7 @@
     "@opentelemetry/node": "^0.19.0",
     "@opentelemetry/propagator-grpc-census-binary": "^0.15.0",
     "@opentelemetry/tracing": "^0.19.0",
-    "grpc": "^1.24.2",
-    "node-pre-gyp": "0.12.0"
+    "grpc": "^1.24.2"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js#readme",
   "devDependencies": {
diff --git a/examples/grpc_dynamic_codegen/package.json b/examples/grpc_dynamic_codegen/package.json
index 832f132f9f5..e761177b4b0 100644
--- a/examples/grpc_dynamic_codegen/package.json
+++ b/examples/grpc_dynamic_codegen/package.json
@@ -34,8 +34,7 @@
     "@opentelemetry/node": "^0.19.0",
     "@opentelemetry/instrumentation-grpc": "^0.19.0",
     "@opentelemetry/tracing": "^0.19.0",
-    "grpc": "^1.24.6",
-    "node-pre-gyp": "^0.17.0"
+    "grpc": "^1.24.6"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js#readme",
   "devDependencies": {
diff --git a/metapackages/auto-instrumentations-node/package.json b/metapackages/auto-instrumentations-node/package.json
index ab64390e530..5b8eb6a4235 100644
--- a/metapackages/auto-instrumentations-node/package.json
+++ b/metapackages/auto-instrumentations-node/package.json
@@ -37,7 +37,6 @@
     "rimraf": "3.0.2",
     "sinon": "10.0.0",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
diff --git a/metapackages/auto-instrumentations-web/package.json b/metapackages/auto-instrumentations-web/package.json
index 1fc92b0155d..ee6cb47d9d7 100644
--- a/metapackages/auto-instrumentations-web/package.json
+++ b/metapackages/auto-instrumentations-web/package.json
@@ -48,7 +48,6 @@
     "sinon": "10.0.0",
     "ts-loader": "8.0.14",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.1.1",
     "typescript": "4.1.3",
     "webpack": "4.46.0",
     "webpack-cli": "4.3.1",
diff --git a/packages/opentelemetry-host-metrics/package.json b/packages/opentelemetry-host-metrics/package.json
index d12b91963c4..f42a6012974 100644
--- a/packages/opentelemetry-host-metrics/package.json
+++ b/packages/opentelemetry-host-metrics/package.json
@@ -42,22 +42,16 @@
     "access": "public"
   },
   "devDependencies": {
-    "@opentelemetry/exporter-prometheus": "0.19.0",
     "@types/mocha": "8.0.2",
     "@types/node": "14.0.27",
     "@types/sinon": "9.0.4",
     "codecov": "3.8.0",
     "gts": "3.1.0",
     "mocha": "7.2.0",
-    "mock-require": "3.0.3",
-    "nan": "2.14.2",
     "nyc": "15.1.0",
     "rimraf": "3.0.2",
-    "semver": "7.3.2",
     "sinon": "10.0.0",
-    "ts-loader": "8.0.7",
     "ts-mocha": "8.0.0",
-    "ts-node": "8.10.2",
     "typescript": "4.1.3"
   },
   "dependencies": {
diff --git a/packages/opentelemetry-test-utils/package.json b/packages/opentelemetry-test-utils/package.json
index 6e5235c6330..080661f591a 100644
--- a/packages/opentelemetry-test-utils/package.json
+++ b/packages/opentelemetry-test-utils/package.json
@@ -26,7 +26,6 @@
   "devDependencies": {
     "@types/node": "14.6.0",
     "gts": "3.1.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
diff --git a/plugins/node/opentelemetry-instrumentation-aws-lambda/package.json b/plugins/node/opentelemetry-instrumentation-aws-lambda/package.json
index 005d0e3629b..bfc00e4c5f1 100644
--- a/plugins/node/opentelemetry-instrumentation-aws-lambda/package.json
+++ b/plugins/node/opentelemetry-instrumentation-aws-lambda/package.json
@@ -41,23 +41,16 @@
     "access": "public"
   },
   "devDependencies": {
-    "@opentelemetry/core": "0.19.0",
     "@opentelemetry/node": "0.19.0",
     "@types/aws-lambda": "8.10.73",
     "@types/mocha": "7.0.2",
     "@types/node": "14.0.27",
-    "@types/semver": "7.3.1",
-    "@types/shimmer": "1.0.1",
-    "@types/sinon": "9.0.4",
     "codecov": "3.7.2",
-    "copyfiles": "2.4.1",
     "gts": "2.0.2",
     "mocha": "7.2.0",
     "nyc": "15.1.0",
     "rimraf": "3.0.2",
-    "sinon": "9.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "3.9.7"
diff --git a/plugins/node/opentelemetry-instrumentation-bunyan/package.json b/plugins/node/opentelemetry-instrumentation-bunyan/package.json
index ce1fe9f0028..5f722d101ea 100644
--- a/plugins/node/opentelemetry-instrumentation-bunyan/package.json
+++ b/plugins/node/opentelemetry-instrumentation-bunyan/package.json
@@ -43,7 +43,6 @@
   },
   "devDependencies": {
     "@opentelemetry/context-async-hooks": "0.19.0",
-    "@opentelemetry/core": "0.19.0",
     "@opentelemetry/node": "0.19.0",
     "@opentelemetry/tracing": "0.19.0",
     "@types/mocha": "7.0.2",
@@ -58,7 +57,6 @@
     "rimraf": "3.0.2",
     "sinon": "9.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
diff --git a/plugins/node/opentelemetry-instrumentation-dns/package.json b/plugins/node/opentelemetry-instrumentation-dns/package.json
index d663ee7a01a..1dd79a5dcdd 100644
--- a/plugins/node/opentelemetry-instrumentation-dns/package.json
+++ b/plugins/node/opentelemetry-instrumentation-dns/package.json
@@ -56,7 +56,6 @@
     "rimraf": "3.0.2",
     "sinon": "10.0.0",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "3.9.7"
diff --git a/plugins/node/opentelemetry-instrumentation-express/package.json b/plugins/node/opentelemetry-instrumentation-express/package.json
index a44eaab1255..7fa14756ab1 100644
--- a/plugins/node/opentelemetry-instrumentation-express/package.json
+++ b/plugins/node/opentelemetry-instrumentation-express/package.json
@@ -55,7 +55,6 @@
     "nyc": "15.1.0",
     "rimraf": "3.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
diff --git a/plugins/node/opentelemetry-instrumentation-graphql/package.json b/plugins/node/opentelemetry-instrumentation-graphql/package.json
index 5075460b095..aa0b1f01110 100644
--- a/plugins/node/opentelemetry-instrumentation-graphql/package.json
+++ b/plugins/node/opentelemetry-instrumentation-graphql/package.json
@@ -47,17 +47,13 @@
     "@types/graphql": "14.5.0",
     "@types/mocha": "8.0.1",
     "@types/node": "14.0.27",
-    "@types/semver": "7.3.1",
     "codecov": "3.7.2",
     "graphql": "15.4.0",
     "gts": "3.1.0",
     "mocha": "7.2.0",
     "nyc": "15.1.0",
     "rimraf": "3.0.2",
-    "semver": "7.3.2",
-    "shimmer": "1.2.1",
     "ts-mocha": "8.0.0",
-    "ts-node": "8.10.2",
     "typescript": "4.1.3"
   },
   "dependencies": {
diff --git a/plugins/node/opentelemetry-instrumentation-hapi/README.md b/plugins/node/opentelemetry-instrumentation-hapi/README.md
index 98af4136857..2e9d20084e6 100644
--- a/plugins/node/opentelemetry-instrumentation-hapi/README.md
+++ b/plugins/node/opentelemetry-instrumentation-hapi/README.md
@@ -68,6 +68,10 @@ registerInstrumentations({
 
 See [examples/hapi](https://github.com/open-telemetry/opentelemetry-js-contrib/tree/main/examples/hapi) for a short example using Hapi
 
+<!-- 
+The dev dependency of `@hapi/podium@4.1.1` is required to force the compatible type declarations. See: https://github.com/hapijs/hapi/issues/4240
+-->
+
 ## Hapi Instrumentation Support
 This package provides automatic tracing for hapi server routes and [request lifecycle](https://github.com/hapijs/hapi/blob/main/API.md#request-lifecycle) extensions defined either directly or via a Hapi plugin.
 
diff --git a/plugins/node/opentelemetry-instrumentation-hapi/package.json b/plugins/node/opentelemetry-instrumentation-hapi/package.json
index 2339fbeaf78..288ba61eab7 100644
--- a/plugins/node/opentelemetry-instrumentation-hapi/package.json
+++ b/plugins/node/opentelemetry-instrumentation-hapi/package.json
@@ -56,7 +56,6 @@
     "rimraf": "3.0.2",
     "semver": "7.3.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
diff --git a/plugins/node/opentelemetry-instrumentation-ioredis/package.json b/plugins/node/opentelemetry-instrumentation-ioredis/package.json
index d9bd3801be9..a05b6893dd3 100644
--- a/plugins/node/opentelemetry-instrumentation-ioredis/package.json
+++ b/plugins/node/opentelemetry-instrumentation-ioredis/package.json
@@ -60,7 +60,6 @@
     "nyc": "15.1.0",
     "rimraf": "3.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "3.9.7"
diff --git a/plugins/node/opentelemetry-instrumentation-koa/package.json b/plugins/node/opentelemetry-instrumentation-koa/package.json
index 6bd7c94c6ff..99ff60acac8 100644
--- a/plugins/node/opentelemetry-instrumentation-koa/package.json
+++ b/plugins/node/opentelemetry-instrumentation-koa/package.json
@@ -58,14 +58,12 @@
     "nyc": "15.1.0",
     "rimraf": "3.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
   },
   "dependencies": {
     "@opentelemetry/api": "^1.0.0-rc.0",
-    "@opentelemetry/core": "^0.19.0",
     "@opentelemetry/instrumentation": "^0.19.0",
     "@opentelemetry/semantic-conventions": "^0.19.0"
   }
diff --git a/plugins/node/opentelemetry-instrumentation-mongodb/package.json b/plugins/node/opentelemetry-instrumentation-mongodb/package.json
index 308b4a1e1ca..e2c89ac2377 100644
--- a/plugins/node/opentelemetry-instrumentation-mongodb/package.json
+++ b/plugins/node/opentelemetry-instrumentation-mongodb/package.json
@@ -56,7 +56,6 @@
     "nyc": "15.1.0",
     "rimraf": "3.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
diff --git a/plugins/node/opentelemetry-instrumentation-mysql/package.json b/plugins/node/opentelemetry-instrumentation-mysql/package.json
index 123d51d7182..8a237b51757 100644
--- a/plugins/node/opentelemetry-instrumentation-mysql/package.json
+++ b/plugins/node/opentelemetry-instrumentation-mysql/package.json
@@ -54,7 +54,6 @@
     "nyc": "15.1.0",
     "rimraf": "3.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
diff --git a/plugins/node/opentelemetry-instrumentation-net/package.json b/plugins/node/opentelemetry-instrumentation-net/package.json
index 11ca9be7510..5809de27521 100644
--- a/plugins/node/opentelemetry-instrumentation-net/package.json
+++ b/plugins/node/opentelemetry-instrumentation-net/package.json
@@ -42,7 +42,6 @@
     "access": "public"
   },
   "devDependencies": {
-    "@opentelemetry/core": "0.19.0",
     "@opentelemetry/node": "0.19.0",
     "@opentelemetry/tracing": "0.19.0",
     "@types/mocha": "7.0.2",
@@ -55,7 +54,6 @@
     "rimraf": "3.0.2",
     "sinon": "10.0.0",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
diff --git a/plugins/node/opentelemetry-instrumentation-pg/package.json b/plugins/node/opentelemetry-instrumentation-pg/package.json
index 849f20600b1..96eee59ad76 100644
--- a/plugins/node/opentelemetry-instrumentation-pg/package.json
+++ b/plugins/node/opentelemetry-instrumentation-pg/package.json
@@ -64,7 +64,6 @@
     "pg-pool": "3.2.1",
     "rimraf": "3.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
diff --git a/plugins/node/opentelemetry-instrumentation-redis/package.json b/plugins/node/opentelemetry-instrumentation-redis/package.json
index 094c74bcc78..74d94d066e9 100644
--- a/plugins/node/opentelemetry-instrumentation-redis/package.json
+++ b/plugins/node/opentelemetry-instrumentation-redis/package.json
@@ -58,7 +58,6 @@
     "redis": "3.0.2",
     "rimraf": "3.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
diff --git a/plugins/node/opentelemetry-instrumentation-restify/package.json b/plugins/node/opentelemetry-instrumentation-restify/package.json
index a5b6095a6d4..eee977af515 100644
--- a/plugins/node/opentelemetry-instrumentation-restify/package.json
+++ b/plugins/node/opentelemetry-instrumentation-restify/package.json
@@ -54,14 +54,12 @@
     "restify": "^4.3.4",
     "rimraf": "3.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
   },
   "dependencies": {
     "@opentelemetry/api": "^1.0.0-rc.0",
-    "@opentelemetry/core": "^0.19.0",
     "@opentelemetry/instrumentation": "^0.19.0",
     "@opentelemetry/semantic-conventions": "^0.19.0"
   }
diff --git a/plugins/node/opentelemetry-instrumentation-winston/package.json b/plugins/node/opentelemetry-instrumentation-winston/package.json
index 25c41961c17..e2df1fc36f6 100644
--- a/plugins/node/opentelemetry-instrumentation-winston/package.json
+++ b/plugins/node/opentelemetry-instrumentation-winston/package.json
@@ -55,7 +55,6 @@
     "rimraf": "3.0.2",
     "sinon": "9.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3",
diff --git a/plugins/web/opentelemetry-instrumentation-document-load/package.json b/plugins/web/opentelemetry-instrumentation-document-load/package.json
index 97090266fd3..4c201bc403b 100644
--- a/plugins/web/opentelemetry-instrumentation-document-load/package.json
+++ b/plugins/web/opentelemetry-instrumentation-document-load/package.json
@@ -63,7 +63,6 @@
     "sinon": "10.0.0",
     "ts-loader": "8.0.0",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3",
diff --git a/plugins/web/opentelemetry-instrumentation-user-interaction/package.json b/plugins/web/opentelemetry-instrumentation-user-interaction/package.json
index 42a9ac98cfb..4b8bd58fa03 100644
--- a/plugins/web/opentelemetry-instrumentation-user-interaction/package.json
+++ b/plugins/web/opentelemetry-instrumentation-user-interaction/package.json
@@ -69,7 +69,6 @@
     "sinon": "10.0.0",
     "ts-loader": "8.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3",
diff --git a/plugins/web/opentelemetry-plugin-react-load/package.json b/plugins/web/opentelemetry-plugin-react-load/package.json
index 0e068a144ca..9a142ad860e 100644
--- a/plugins/web/opentelemetry-plugin-react-load/package.json
+++ b/plugins/web/opentelemetry-plugin-react-load/package.json
@@ -70,7 +70,6 @@
     "sinon": "10.0.0",
     "ts-loader": "8.0.4",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3",
diff --git a/propagators/opentelemetry-propagator-grpc-census-binary/package.json b/propagators/opentelemetry-propagator-grpc-census-binary/package.json
index 489b3aec74b..2cda7a8b49e 100644
--- a/propagators/opentelemetry-propagator-grpc-census-binary/package.json
+++ b/propagators/opentelemetry-propagator-grpc-census-binary/package.json
@@ -52,13 +52,11 @@
     "rimraf": "3.0.2",
     "ts-loader": "8.0.2",
     "ts-mocha": "8.0.0",
-    "ts-node": "9.0.0",
     "tslint-consistent-codestyle": "1.16.0",
     "tslint-microsoft-contrib": "6.2.0",
     "typescript": "4.1.3"
   },
   "dependencies": {
-    "@opentelemetry/api": "^1.0.0-rc.0",
-    "@opentelemetry/core": "^0.19.0"
+    "@opentelemetry/api": "^1.0.0-rc.0"
   }
 }
diff --git a/propagators/opentelemetry-propagator-ot-trace/package.json b/propagators/opentelemetry-propagator-ot-trace/package.json
index 94c63831670..d49fc0910eb 100644
--- a/propagators/opentelemetry-propagator-ot-trace/package.json
+++ b/propagators/opentelemetry-propagator-ot-trace/package.json
@@ -60,7 +60,6 @@
     "karma-webpack": "4.0.2",
     "mocha": "7.2.0",
     "nyc": "15.1.0",
-    "rimraf": "3.0.2",
     "ts-loader": "8.0.12",
     "ts-mocha": "8.0.0",
     "typescript": "4.1.3",