diff --git a/detectors/node/opentelemetry-resource-detector-github/package.json b/detectors/node/opentelemetry-resource-detector-github/package.json
index 0f20874e115..c6572be0aac 100644
--- a/detectors/node/opentelemetry-resource-detector-github/package.json
+++ b/detectors/node/opentelemetry-resource-detector-github/package.json
@@ -43,10 +43,10 @@
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   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
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-    "@opentelemetry/api": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
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     "@types/sinon": "10.0.2",
@@ -60,6 +60,6 @@
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   },
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-    "@opentelemetry/resources": "^0.20.0"
+    "@opentelemetry/resources": "^0.21.0"
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 }
diff --git a/examples/dns/package.json b/examples/dns/package.json
index 90058ac28a7..04842e386cb 100644
--- a/examples/dns/package.json
+++ b/examples/dns/package.json
@@ -26,13 +26,13 @@
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-    "@opentelemetry/exporter-zipkin": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
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-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0"
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js-contrib#readme",
   "devDependencies": {
diff --git a/examples/express/package.json b/examples/express/package.json
index 7f38c7e4401..8d74c5f2b49 100644
--- a/examples/express/package.json
+++ b/examples/express/package.json
@@ -28,14 +28,14 @@
     "url": "https://github.com/open-telemetry/opentelemetry-js/issues"
   },
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-    "@opentelemetry/exporter-zipkin": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
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-    "@opentelemetry/instrumentation-http": "^0.20.0",
-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "axios": "^0.21.1",
     "cross-env": "^7.0.3",
     "express": "^4.17.1"
diff --git a/examples/graphql/package.json b/examples/graphql/package.json
index ce7133e4668..a8982b0ae59 100644
--- a/examples/graphql/package.json
+++ b/examples/graphql/package.json
@@ -31,13 +31,13 @@
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   },
   "dependencies": {
-    "@opentelemetry/exporter-collector": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/exporter-collector": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
     "@opentelemetry/instrumentation-graphql": "^0.15.0",
-    "@opentelemetry/node": "^0.20.0",
+    "@opentelemetry/node": "^0.21.0",
     "@opentelemetry/instrumentation-express": "^0.15.0",
-    "@opentelemetry/instrumentation-http": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "apollo-server": "^2.18.1",
     "express": "^4.17.1",
     "express-graphql": "^0.11.0",
diff --git a/examples/grpc-census-prop/package.json b/examples/grpc-census-prop/package.json
index 695373d8129..ba710b307b3 100644
--- a/examples/grpc-census-prop/package.json
+++ b/examples/grpc-census-prop/package.json
@@ -34,13 +34,13 @@
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-    "@opentelemetry/instrumentation-grpc": "^0.20.0",
-    "@opentelemetry/node": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/instrumentation-grpc": "^0.21.0",
+    "@opentelemetry/node": "^0.21.0",
     "@opentelemetry/propagator-grpc-census-binary": "^0.15.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "grpc": "^1.24.2"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js#readme",
diff --git a/examples/grpc_dynamic_codegen/package.json b/examples/grpc_dynamic_codegen/package.json
index b559f28def1..5762f2e2eb3 100644
--- a/examples/grpc_dynamic_codegen/package.json
+++ b/examples/grpc_dynamic_codegen/package.json
@@ -28,12 +28,12 @@
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-    "@opentelemetry/instrumentation-grpc": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/instrumentation-grpc": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "grpc": "^1.24.6"
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   "homepage": "https://github.com/open-telemetry/opentelemetry-js#readme",
diff --git a/examples/hapi/package.json b/examples/hapi/package.json
index 686a6192f50..cf1004fdc7b 100644
--- a/examples/hapi/package.json
+++ b/examples/hapi/package.json
@@ -32,14 +32,14 @@
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-    "@opentelemetry/exporter-zipkin": "^0.20.0",
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+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
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-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "axios": "^0.21.1"
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   "homepage": "https://github.com/open-telemetry/opentelemetry-js-contrib#readme",
diff --git a/examples/host-metrics/package.json b/examples/host-metrics/package.json
index 57620a5cfd3..620b5a52052 100644
--- a/examples/host-metrics/package.json
+++ b/examples/host-metrics/package.json
@@ -26,13 +26,13 @@
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   },
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-    "@opentelemetry/exporter-collector": "^0.20.0",
-    "@opentelemetry/exporter-prometheus": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/exporter-collector": "^0.21.0",
+    "@opentelemetry/exporter-prometheus": "^0.21.0",
     "@opentelemetry/host-metrics": "^0.15.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/metrics": "^0.20.0"
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/metrics": "^0.21.0"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js#readme"
 }
diff --git a/examples/ioredis/package.json b/examples/ioredis/package.json
index 0d0dab0be60..7f69c8e686a 100644
--- a/examples/ioredis/package.json
+++ b/examples/ioredis/package.json
@@ -28,12 +28,12 @@
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-    "@opentelemetry/exporter-jaeger": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
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-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "ioredis": "^4.22.0"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js-contrib#readme"
diff --git a/examples/koa/package.json b/examples/koa/package.json
index 8bcc215491c..7270bba1bb7 100644
--- a/examples/koa/package.json
+++ b/examples/koa/package.json
@@ -32,14 +32,14 @@
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-    "@opentelemetry/instrumentation-http": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
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-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "axios": "^0.21.1",
     "koa": "^2.13.0"
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diff --git a/examples/meta-node/package.json b/examples/meta-node/package.json
index 85857107d97..01fac4275a1 100644
--- a/examples/meta-node/package.json
+++ b/examples/meta-node/package.json
@@ -35,12 +35,12 @@
     "eslint": "^7.4.0"
   },
   "dependencies": {
-    "@opentelemetry/api": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
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-    "@opentelemetry/exporter-collector": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/exporter-collector": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "axios": "^0.21.1",
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   }
diff --git a/examples/mongodb/package.json b/examples/mongodb/package.json
index 347cd14aa2d..8db69530aa3 100644
--- a/examples/mongodb/package.json
+++ b/examples/mongodb/package.json
@@ -28,14 +28,14 @@
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   },
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-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/instrumentation-http": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
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-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "mongodb": "^3.5.7"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js-contrib#readme",
diff --git a/examples/mysql/package.json b/examples/mysql/package.json
index 0ca199c9c75..20961bb9144 100644
--- a/examples/mysql/package.json
+++ b/examples/mysql/package.json
@@ -28,14 +28,14 @@
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   },
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-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/instrumentation-http": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
     "@opentelemetry/instrumentation-mysql": "^0.15.0",
-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "mysql": "*"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js#readme",
diff --git a/examples/network/package.json b/examples/network/package.json
index d8c1ee26a6a..cd76f6c3676 100644
--- a/examples/network/package.json
+++ b/examples/network/package.json
@@ -27,15 +27,15 @@
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-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
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-    "@opentelemetry/instrumentation-http": "^0.20.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
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-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0"
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0"
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diff --git a/examples/postgres/package.json b/examples/postgres/package.json
index 36dfe5bd1ee..c3368fa6ace 100644
--- a/examples/postgres/package.json
+++ b/examples/postgres/package.json
@@ -30,14 +30,14 @@
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   },
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-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/instrumentation-http": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
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-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
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diff --git a/examples/react-load/preact/package.json b/examples/react-load/preact/package.json
index 8d2cb06ec0b..1ea1d03c4d3 100644
--- a/examples/react-load/preact/package.json
+++ b/examples/react-load/preact/package.json
@@ -37,11 +37,11 @@
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-    "@opentelemetry/context-zone": "^0.20.0",
-    "@opentelemetry/exporter-collector": "^0.20.0",
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+    "@opentelemetry/exporter-collector": "^0.21.0",
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-    "@opentelemetry/tracing": "^0.20.0",
-    "@opentelemetry/web": "^0.20.0",
+    "@opentelemetry/tracing": "^0.21.0",
+    "@opentelemetry/web": "^0.21.0",
     "preact": "^10.3.2",
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diff --git a/examples/react-load/react/package.json b/examples/react-load/react/package.json
index 06080bae929..26a3eb06d33 100644
--- a/examples/react-load/react/package.json
+++ b/examples/react-load/react/package.json
@@ -36,12 +36,12 @@
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-    "@opentelemetry/exporter-collector": "^0.20.0",
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diff --git a/examples/redis/package.json b/examples/redis/package.json
index 178bc4640a4..f570ce9a012 100644
--- a/examples/redis/package.json
+++ b/examples/redis/package.json
@@ -30,14 +30,14 @@
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+    "@opentelemetry/instrumentation-http": "^0.21.0",
     "@opentelemetry/instrumentation-redis": "^0.15.0",
-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "axios": "^0.21.1",
     "express": "^4.17.1",
     "redis": "^2.8.0"
diff --git a/examples/restify/package.json b/examples/restify/package.json
index a25112fe644..5de7c0f6530 100644
--- a/examples/restify/package.json
+++ b/examples/restify/package.json
@@ -28,14 +28,14 @@
     "url": "https://github.com/open-telemetry/opentelemetry-js/issues"
   },
   "dependencies": {
-    "@opentelemetry/api": "^0.20.0",
-    "@opentelemetry/exporter-jaeger": "^0.20.0",
-    "@opentelemetry/exporter-zipkin": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/instrumentation-http": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
     "@opentelemetry/instrumentation-restify": "^0.16.0",
-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "restify": "^4.3.4"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js#readme",
diff --git a/examples/router/package.json b/examples/router/package.json
index 4d86ceb1071..ed694f1c1d8 100644
--- a/examples/router/package.json
+++ b/examples/router/package.json
@@ -28,14 +28,14 @@
     "url": "https://github.com/open-telemetry/opentelemetry-js/issues"
   },
   "dependencies": {
-    "@opentelemetry/api": "^0.20.0",
-    "@opentelemetry/exporter-jaeger": "^0.20.0",
-    "@opentelemetry/exporter-zipkin": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/instrumentation-http": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
+    "@opentelemetry/exporter-jaeger": "^0.21.0",
+    "@opentelemetry/exporter-zipkin": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
     "@opentelemetry/instrumentation-router": "^0.16.0",
-    "@opentelemetry/node": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/node": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "router": "^1.3.5"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js#readme",
diff --git a/examples/web/package.json b/examples/web/package.json
index 9c1a4a3b949..0cd044211e9 100644
--- a/examples/web/package.json
+++ b/examples/web/package.json
@@ -34,18 +34,18 @@
     "webpack-merge": "^4.2.2"
   },
   "dependencies": {
-    "@opentelemetry/api": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
     "@opentelemetry/auto-instrumentations-web": "^0.16.0",
-    "@opentelemetry/context-zone": "^0.20.0",
-    "@opentelemetry/core": "^0.20.0",
-    "@opentelemetry/exporter-collector": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/context-zone": "^0.21.0",
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/exporter-collector": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
     "@opentelemetry/instrumentation-document-load": "^0.16.0",
     "@opentelemetry/instrumentation-user-interaction": "^0.16.0",
-    "@opentelemetry/instrumentation-xml-http-request": "^0.20.0",
-    "@opentelemetry/propagator-b3": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
-    "@opentelemetry/web": "^0.20.0"
+    "@opentelemetry/instrumentation-xml-http-request": "^0.21.0",
+    "@opentelemetry/propagator-b3": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
+    "@opentelemetry/web": "^0.21.0"
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js-contrib#readme"
 }
diff --git a/metapackages/auto-instrumentations-node/package.json b/metapackages/auto-instrumentations-node/package.json
index 850f23724eb..a131be4eee8 100644
--- a/metapackages/auto-instrumentations-node/package.json
+++ b/metapackages/auto-instrumentations-node/package.json
@@ -27,10 +27,10 @@
     "url": "https://github.com/open-telemetry/opentelemetry-js-contrib/issues"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "@types/sinon": "10.0.2",
@@ -44,12 +44,12 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
     "@opentelemetry/instrumentation-dns": "^0.20.0",
     "@opentelemetry/instrumentation-express": "^0.20.0",
     "@opentelemetry/instrumentation-graphql": "^0.20.0",
-    "@opentelemetry/instrumentation-grpc": "^0.20.0",
-    "@opentelemetry/instrumentation-http": "^0.20.0",
+    "@opentelemetry/instrumentation-grpc": "^0.21.0",
+    "@opentelemetry/instrumentation-http": "^0.21.0",
     "@opentelemetry/instrumentation-ioredis": "^0.20.0",
     "@opentelemetry/instrumentation-koa": "^0.20.0",
     "@opentelemetry/instrumentation-mongodb": "^0.20.0",
diff --git a/metapackages/auto-instrumentations-web/package.json b/metapackages/auto-instrumentations-web/package.json
index 143b9a59147..5c849a33a6b 100644
--- a/metapackages/auto-instrumentations-web/package.json
+++ b/metapackages/auto-instrumentations-web/package.json
@@ -28,11 +28,11 @@
     "url": "https://github.com/open-telemetry/opentelemetry-js-contrib/issues"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
     "@babel/core": "7.14.3",
-    "@opentelemetry/api": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
     "@types/mocha": "8.2.2",
     "@types/node": "14.17.2",
     "@types/sinon": "10.0.2",
@@ -59,10 +59,10 @@
     "webpack-merge": "5.7.3"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
     "@opentelemetry/instrumentation-document-load": "^0.20.0",
-    "@opentelemetry/instrumentation-fetch": "^0.20.0",
+    "@opentelemetry/instrumentation-fetch": "^0.21.0",
     "@opentelemetry/instrumentation-user-interaction": "^0.20.0",
-    "@opentelemetry/instrumentation-xml-http-request": "^0.20.0"
+    "@opentelemetry/instrumentation-xml-http-request": "^0.21.0"
   }
 }
diff --git a/packages/opentelemetry-host-metrics/package.json b/packages/opentelemetry-host-metrics/package.json
index 5205a4efffe..4fed019570d 100644
--- a/packages/opentelemetry-host-metrics/package.json
+++ b/packages/opentelemetry-host-metrics/package.json
@@ -42,10 +42,10 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
     "@types/mocha": "8.2.2",
     "@types/node": "14.17.2",
     "@types/sinon": "10.0.2",
@@ -59,9 +59,9 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/api-metrics": "^0.20.0",
-    "@opentelemetry/core": "^0.20.0",
-    "@opentelemetry/metrics": "^0.20.0",
+    "@opentelemetry/api-metrics": "^0.21.0",
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/metrics": "^0.21.0",
     "systeminformation": "^5.0.0"
   }
 }
diff --git a/packages/opentelemetry-id-generator-aws-xray/package.json b/packages/opentelemetry-id-generator-aws-xray/package.json
index ce928f3c48f..d74619b27c6 100644
--- a/packages/opentelemetry-id-generator-aws-xray/package.json
+++ b/packages/opentelemetry-id-generator-aws-xray/package.json
@@ -52,10 +52,10 @@
     "README.md"
   ],
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
     "@types/mocha": "8.2.2",
     "@types/node": "14.17.2",
     "@types/sinon": "10.0.2",
@@ -79,6 +79,6 @@
     "webpack": "4.46.0"
   },
   "dependencies": {
-    "@opentelemetry/core": "^0.20.0"
+    "@opentelemetry/core": "^0.21.0"
   }
 }
diff --git a/packages/opentelemetry-test-utils/package.json b/packages/opentelemetry-test-utils/package.json
index c308421aa98..1c79c8d136f 100644
--- a/packages/opentelemetry-test-utils/package.json
+++ b/packages/opentelemetry-test-utils/package.json
@@ -24,16 +24,16 @@
   },
   "homepage": "https://github.com/open-telemetry/opentelemetry-js#readme",
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
     "@types/node": "14.17.2",
     "gts": "3.1.0",
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/core": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0"
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-aws-lambda/package.json b/plugins/node/opentelemetry-instrumentation-aws-lambda/package.json
index 304358ed14d..4769a8edab8 100644
--- a/plugins/node/opentelemetry-instrumentation-aws-lambda/package.json
+++ b/plugins/node/opentelemetry-instrumentation-aws-lambda/package.json
@@ -41,12 +41,12 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/core": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/core": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
@@ -58,11 +58,11 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
     "@opentelemetry/propagator-aws-xray": "^0.20.0",
-    "@opentelemetry/resources": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
+    "@opentelemetry/resources": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
     "@types/aws-lambda": "8.10.77"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-bunyan/package.json b/plugins/node/opentelemetry-instrumentation-bunyan/package.json
index 3b05b41b71c..ca68022f8a8 100644
--- a/plugins/node/opentelemetry-instrumentation-bunyan/package.json
+++ b/plugins/node/opentelemetry-instrumentation-bunyan/package.json
@@ -42,13 +42,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "@types/sinon": "10.0.2",
@@ -63,7 +63,7 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
     "@types/bunyan": "1.8.6"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-bunyan/test/bunyan.test.ts b/plugins/node/opentelemetry-instrumentation-bunyan/test/bunyan.test.ts
index 1c8b9f7ed79..69d598d55b9 100644
--- a/plugins/node/opentelemetry-instrumentation-bunyan/test/bunyan.test.ts
+++ b/plugins/node/opentelemetry-instrumentation-bunyan/test/bunyan.test.ts
@@ -18,7 +18,7 @@ import {
   InMemorySpanExporter,
   SimpleSpanProcessor,
 } from '@opentelemetry/tracing';
-import { context, trace, NoopTracerProvider } from '@opentelemetry/api';
+import { context, INVALID_SPAN_CONTEXT, trace } from '@opentelemetry/api';
 import { NodeTracerProvider } from '@opentelemetry/node';
 import { isWrapped } from '@opentelemetry/instrumentation';
 import { AsyncHooksContextManager } from '@opentelemetry/context-async-hooks';
@@ -101,8 +101,7 @@ describe('BunyanInstrumentation', () => {
     });
 
     it('does not inject span context if span context is invalid', () => {
-      const noopTracer = new NoopTracerProvider().getTracer('noop');
-      const span = noopTracer.startSpan('noop');
+      const span = trace.wrapSpanContext(INVALID_SPAN_CONTEXT);
       context.with(trace.setSpan(context.active(), span), () => {
         logger.info('foo');
         sinon.assert.calledOnce(writeSpy);
diff --git a/plugins/node/opentelemetry-instrumentation-dns/package.json b/plugins/node/opentelemetry-instrumentation-dns/package.json
index 7642c744f4c..99f5374e8b5 100644
--- a/plugins/node/opentelemetry-instrumentation-dns/package.json
+++ b/plugins/node/opentelemetry-instrumentation-dns/package.json
@@ -41,13 +41,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/core": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/core": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "@types/semver": "7.3.6",
@@ -63,8 +63,8 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "semver": "^7.3.2"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-express/package.json b/plugins/node/opentelemetry-instrumentation-express/package.json
index 7083db4ae10..06aa326f4cb 100644
--- a/plugins/node/opentelemetry-instrumentation-express/package.json
+++ b/plugins/node/opentelemetry-instrumentation-express/package.json
@@ -42,13 +42,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
@@ -61,9 +61,9 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/core": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "@types/express": "4.17.12"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-express/src/instrumentation.ts b/plugins/node/opentelemetry-instrumentation-express/src/instrumentation.ts
index aea093d3f02..e8a9b6199a9 100644
--- a/plugins/node/opentelemetry-instrumentation-express/src/instrumentation.ts
+++ b/plugins/node/opentelemetry-instrumentation-express/src/instrumentation.ts
@@ -260,7 +260,7 @@ export class ExpressInstrumentation extends InstrumentationBase<
               (req[_LAYERS_STORE_PROPERTY] as string[]).pop();
             }
             const callback = args[callbackIdx] as Function;
-            return context.bind(callback, newContext).apply(this, arguments);
+            return context.bind(newContext, callback).apply(this, arguments);
           };
         }
         const result = original.apply(this, arguments);
diff --git a/plugins/node/opentelemetry-instrumentation-generic-pool/package.json b/plugins/node/opentelemetry-instrumentation-generic-pool/package.json
index 47b03983f59..909a87e727a 100644
--- a/plugins/node/opentelemetry-instrumentation-generic-pool/package.json
+++ b/plugins/node/opentelemetry-instrumentation-generic-pool/package.json
@@ -41,13 +41,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "@types/semver": "7.3.6",
@@ -62,8 +62,8 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "@types/generic-pool": "^3.1.9"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-graphql/package.json b/plugins/node/opentelemetry-instrumentation-graphql/package.json
index 8cd35db62ec..e10b47946d1 100644
--- a/plugins/node/opentelemetry-instrumentation-graphql/package.json
+++ b/plugins/node/opentelemetry-instrumentation-graphql/package.json
@@ -43,11 +43,11 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "8.2.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
@@ -60,7 +60,7 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
     "@types/graphql": "14.5.0"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-hapi/package.json b/plugins/node/opentelemetry-instrumentation-hapi/package.json
index 880c94d2c52..06507e4f117 100644
--- a/plugins/node/opentelemetry-instrumentation-hapi/package.json
+++ b/plugins/node/opentelemetry-instrumentation-hapi/package.json
@@ -41,14 +41,14 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
     "@hapi/hapi": "20.1.3",
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.3",
     "codecov": "3.8.2",
@@ -61,8 +61,8 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "@types/hapi__hapi": "20.0.8"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-ioredis/package.json b/plugins/node/opentelemetry-instrumentation-ioredis/package.json
index 013ffe482b4..22590d294c5 100644
--- a/plugins/node/opentelemetry-instrumentation-ioredis/package.json
+++ b/plugins/node/opentelemetry-instrumentation-ioredis/package.json
@@ -44,14 +44,14 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
     "@opentelemetry/test-utils": "^0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
@@ -65,8 +65,8 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "@types/ioredis": "4.26.4"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-knex/package.json b/plugins/node/opentelemetry-instrumentation-knex/package.json
index 5c16f51abe4..9abf75193dd 100644
--- a/plugins/node/opentelemetry-instrumentation-knex/package.json
+++ b/plugins/node/opentelemetry-instrumentation-knex/package.json
@@ -41,13 +41,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.0.27",
     "codecov": "3.7.2",
@@ -61,7 +61,7 @@
     "typescript": "4.1.3"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0"
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-koa/package.json b/plugins/node/opentelemetry-instrumentation-koa/package.json
index 33ea0d16e33..a14c3729575 100644
--- a/plugins/node/opentelemetry-instrumentation-koa/package.json
+++ b/plugins/node/opentelemetry-instrumentation-koa/package.json
@@ -43,14 +43,14 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
     "@koa/router": "9.4.0",
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.3",
     "codecov": "3.8.2",
@@ -63,9 +63,9 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/core": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "@types/koa": "2.13.3",
     "@types/koa__router": "8.0.4"
   }
diff --git a/plugins/node/opentelemetry-instrumentation-mongodb/package.json b/plugins/node/opentelemetry-instrumentation-mongodb/package.json
index ee0e06bdc3c..d7a2da0c9ac 100644
--- a/plugins/node/opentelemetry-instrumentation-mongodb/package.json
+++ b/plugins/node/opentelemetry-instrumentation-mongodb/package.json
@@ -43,13 +43,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
@@ -62,8 +62,8 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "@types/mongodb": "3.6.17"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-mysql/package.json b/plugins/node/opentelemetry-instrumentation-mysql/package.json
index aa8fb50b019..a5fbbb43892 100644
--- a/plugins/node/opentelemetry-instrumentation-mysql/package.json
+++ b/plugins/node/opentelemetry-instrumentation-mysql/package.json
@@ -41,13 +41,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
     "@opentelemetry/test-utils": "^0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
@@ -60,8 +60,8 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "@types/mysql": "2.15.18"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-net/package.json b/plugins/node/opentelemetry-instrumentation-net/package.json
index 4ebbc884ff6..a7fc5ca619f 100644
--- a/plugins/node/opentelemetry-instrumentation-net/package.json
+++ b/plugins/node/opentelemetry-instrumentation-net/package.json
@@ -42,12 +42,12 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "@types/sinon": "10.0.2",
@@ -61,7 +61,7 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0"
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-pg/package.json b/plugins/node/opentelemetry-instrumentation-pg/package.json
index ac411251f71..bf637c45f6b 100644
--- a/plugins/node/opentelemetry-instrumentation-pg/package.json
+++ b/plugins/node/opentelemetry-instrumentation-pg/package.json
@@ -47,14 +47,14 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
     "@opentelemetry/test-utils": "^0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
@@ -69,8 +69,8 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "@types/pg": "8.6.0",
     "@types/pg-pool": "2.0.2"
   }
diff --git a/plugins/node/opentelemetry-instrumentation-pg/src/instrumentation.ts b/plugins/node/opentelemetry-instrumentation-pg/src/instrumentation.ts
index ea106d6c73e..052aa432e14 100644
--- a/plugins/node/opentelemetry-instrumentation-pg/src/instrumentation.ts
+++ b/plugins/node/opentelemetry-instrumentation-pg/src/instrumentation.ts
@@ -169,7 +169,10 @@ export class PgInstrumentation extends InstrumentationBase {
             );
             // If a parent span exists, bind the callback
             if (parentSpan) {
-              args[args.length - 1] = context.bind(args[args.length - 1]);
+              args[args.length - 1] = context.bind(
+                context.active(),
+                args[args.length - 1]
+              );
             }
           } else if (
             typeof (args[0] as NormalizedQueryConfig).callback === 'function'
@@ -181,7 +184,7 @@ export class PgInstrumentation extends InstrumentationBase {
             );
             // If a parent span existed, bind the callback
             if (parentSpan) {
-              callback = context.bind(callback);
+              callback = context.bind(context.active(), callback);
             }
 
             // Copy the callback instead of writing to args.callback so that we don't modify user's
@@ -250,7 +253,7 @@ export class PgInstrumentation extends InstrumentationBase {
           ) as PgPoolCallback;
           // If a parent span exists, bind the callback
           if (parentSpan) {
-            callback = context.bind(callback);
+            callback = context.bind(context.active(), callback);
           }
         }
 
@@ -263,6 +266,7 @@ export class PgInstrumentation extends InstrumentationBase {
         if (connectResult instanceof Promise) {
           const connectResultPromise = connectResult as Promise<unknown>;
           return context.bind(
+            context.active(),
             connectResultPromise
               .then(result => {
                 // Return a pass-along promise which ends the span and then goes to user's orig resolvers
diff --git a/plugins/node/opentelemetry-instrumentation-pino/package.json b/plugins/node/opentelemetry-instrumentation-pino/package.json
index f1d7f7226be..d882f27100a 100644
--- a/plugins/node/opentelemetry-instrumentation-pino/package.json
+++ b/plugins/node/opentelemetry-instrumentation-pino/package.json
@@ -42,13 +42,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "@types/semver": "7.3.6",
@@ -65,7 +65,7 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
     "@types/pino": "6.3.8",
     "semver": "^7.3.5"
   }
diff --git a/plugins/node/opentelemetry-instrumentation-pino/test/pino.test.ts b/plugins/node/opentelemetry-instrumentation-pino/test/pino.test.ts
index 6363fe0900e..4bbad5db033 100644
--- a/plugins/node/opentelemetry-instrumentation-pino/test/pino.test.ts
+++ b/plugins/node/opentelemetry-instrumentation-pino/test/pino.test.ts
@@ -18,7 +18,7 @@ import {
   InMemorySpanExporter,
   SimpleSpanProcessor,
 } from '@opentelemetry/tracing';
-import { context, trace, NoopTracerProvider, Span } from '@opentelemetry/api';
+import { context, trace, Span, INVALID_SPAN_CONTEXT } from '@opentelemetry/api';
 import { NodeTracerProvider } from '@opentelemetry/node';
 import { AsyncHooksContextManager } from '@opentelemetry/context-async-hooks';
 import { Writable } from 'stream';
@@ -128,8 +128,7 @@ describe('PinoInstrumentation', () => {
     });
 
     it('does not inject span context if span context is invalid', () => {
-      const noopTracer = new NoopTracerProvider().getTracer('noop');
-      const span = noopTracer.startSpan('noop');
+      const span = trace.wrapSpanContext(INVALID_SPAN_CONTEXT);
       context.with(trace.setSpan(context.active(), span), () => {
         testNoInjection();
       });
diff --git a/plugins/node/opentelemetry-instrumentation-redis/package.json b/plugins/node/opentelemetry-instrumentation-redis/package.json
index b3b40e8ca9c..2811117edd4 100644
--- a/plugins/node/opentelemetry-instrumentation-redis/package.json
+++ b/plugins/node/opentelemetry-instrumentation-redis/package.json
@@ -43,14 +43,14 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
     "@opentelemetry/test-utils": "^0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
@@ -64,8 +64,8 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "@types/redis": "2.8.29"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-redis/src/utils.ts b/plugins/node/opentelemetry-instrumentation-redis/src/utils.ts
index 854d0b86b32..9ad22b2b435 100644
--- a/plugins/node/opentelemetry-instrumentation-redis/src/utils.ts
+++ b/plugins/node/opentelemetry-instrumentation-redis/src/utils.ts
@@ -48,7 +48,7 @@ const endSpan = (span: Span, err?: Error | null) => {
 export const getTracedCreateClient = (tracer: Tracer, original: Function) => {
   return function createClientTrace(this: redisTypes.RedisClient) {
     const client: redisTypes.RedisClient = original.apply(this, arguments);
-    return context.bind(client);
+    return context.bind(context.active(), client);
   };
 };
 
@@ -63,7 +63,7 @@ export const getTracedCreateStreamTrace = (
           return this._patched_redis_stream;
         },
         set(val: EventEmitter) {
-          context.bind(val);
+          context.bind(context.active(), val);
           this._patched_redis_stream = val;
         },
       });
diff --git a/plugins/node/opentelemetry-instrumentation-restify/package.json b/plugins/node/opentelemetry-instrumentation-restify/package.json
index 7d035f363d7..7de46953b81 100644
--- a/plugins/node/opentelemetry-instrumentation-restify/package.json
+++ b/plugins/node/opentelemetry-instrumentation-restify/package.json
@@ -41,13 +41,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
@@ -60,9 +60,9 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/core": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
     "@types/restify": "4.3.7"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-router/package.json b/plugins/node/opentelemetry-instrumentation-router/package.json
index 60c4e57ef25..7a7b4ca5aff 100644
--- a/plugins/node/opentelemetry-instrumentation-router/package.json
+++ b/plugins/node/opentelemetry-instrumentation-router/package.json
@@ -41,13 +41,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
@@ -62,7 +62,7 @@
     "typescript": "4.3.2"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0"
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-router/test/index.test.ts b/plugins/node/opentelemetry-instrumentation-router/test/index.test.ts
index 6d3b3e143d4..0a29bdef05e 100644
--- a/plugins/node/opentelemetry-instrumentation-router/test/index.test.ts
+++ b/plugins/node/opentelemetry-instrumentation-router/test/index.test.ts
@@ -98,7 +98,7 @@ const createServer = async ({
     });
   };
   const handler = parentSpan
-    ? context.bind(defaultHandler, trace.setSpan(context.active(), parentSpan))
+    ? context.bind(trace.setSpan(context.active(), parentSpan), defaultHandler)
     : defaultHandler;
   const server = http.createServer(handler);
 
diff --git a/plugins/node/opentelemetry-instrumentation-winston/package.json b/plugins/node/opentelemetry-instrumentation-winston/package.json
index d2f415f45bb..9c246d46c7c 100644
--- a/plugins/node/opentelemetry-instrumentation-winston/package.json
+++ b/plugins/node/opentelemetry-instrumentation-winston/package.json
@@ -42,13 +42,13 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-async-hooks": "0.20.0",
-    "@opentelemetry/node": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-async-hooks": "0.21.0",
+    "@opentelemetry/node": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "@types/sinon": "10.0.2",
@@ -64,6 +64,6 @@
     "winston2": "npm:winston@2.4.5"
   },
   "dependencies": {
-    "@opentelemetry/instrumentation": "^0.20.0"
+    "@opentelemetry/instrumentation": "^0.21.0"
   }
 }
diff --git a/plugins/node/opentelemetry-instrumentation-winston/test/winston.test.ts b/plugins/node/opentelemetry-instrumentation-winston/test/winston.test.ts
index 9c5cc1f3c4a..4c6c9cf258b 100644
--- a/plugins/node/opentelemetry-instrumentation-winston/test/winston.test.ts
+++ b/plugins/node/opentelemetry-instrumentation-winston/test/winston.test.ts
@@ -18,7 +18,7 @@ import {
   InMemorySpanExporter,
   SimpleSpanProcessor,
 } from '@opentelemetry/tracing';
-import { context, trace, NoopTracerProvider, Span } from '@opentelemetry/api';
+import { context, trace, Span, INVALID_SPAN_CONTEXT } from '@opentelemetry/api';
 import { NodeTracerProvider } from '@opentelemetry/node';
 import { isWrapped } from '@opentelemetry/instrumentation';
 import { AsyncHooksContextManager } from '@opentelemetry/context-async-hooks';
@@ -115,8 +115,7 @@ describe('WinstonInstrumentation', () => {
     });
 
     it('does not inject span context if span context is invalid', () => {
-      const noopTracer = new NoopTracerProvider().getTracer('noop');
-      const span = noopTracer.startSpan('noop');
+      const span = trace.wrapSpanContext(INVALID_SPAN_CONTEXT);
       context.with(trace.setSpan(context.active(), span), () => {
         testNoInjection();
       });
diff --git a/plugins/web/opentelemetry-instrumentation-document-load/package.json b/plugins/web/opentelemetry-instrumentation-document-load/package.json
index d9bc1ccb428..7c2de91c03f 100644
--- a/plugins/web/opentelemetry-instrumentation-document-load/package.json
+++ b/plugins/web/opentelemetry-instrumentation-document-load/package.json
@@ -47,11 +47,11 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
     "@babel/core": "7.14.3",
-    "@opentelemetry/api": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
     "@types/mocha": "8.2.2",
     "@types/node": "14.17.2",
     "@types/sinon": "10.0.2",
@@ -78,10 +78,10 @@
     "webpack-merge": "5.7.3"
   },
   "dependencies": {
-    "@opentelemetry/core": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
-    "@opentelemetry/web": "^0.20.0"
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
+    "@opentelemetry/web": "^0.21.0"
   }
 }
diff --git a/plugins/web/opentelemetry-instrumentation-user-interaction/package.json b/plugins/web/opentelemetry-instrumentation-user-interaction/package.json
index c34f64386b2..b12f7648fe4 100644
--- a/plugins/web/opentelemetry-instrumentation-user-interaction/package.json
+++ b/plugins/web/opentelemetry-instrumentation-user-interaction/package.json
@@ -48,10 +48,10 @@
   },
   "devDependencies": {
     "@babel/core": "7.14.3",
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/context-zone-peer-dep": "0.20.0",
-    "@opentelemetry/instrumentation-xml-http-request": "0.20.0",
-    "@opentelemetry/tracing": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/context-zone-peer-dep": "0.21.0",
+    "@opentelemetry/instrumentation-xml-http-request": "0.21.0",
+    "@opentelemetry/tracing": "0.21.0",
     "@types/jquery": "3.5.5",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
@@ -81,12 +81,12 @@
     "zone.js": "0.11.4"
   },
   "dependencies": {
-    "@opentelemetry/core": "^0.20.0",
-    "@opentelemetry/instrumentation": "^0.20.0",
-    "@opentelemetry/web": "^0.20.0"
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/instrumentation": "^0.21.0",
+    "@opentelemetry/web": "^0.21.0"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
     "zone.js": "0.11.4"
   },
   "sideEffects": false
diff --git a/plugins/web/opentelemetry-plugin-react-load/package.json b/plugins/web/opentelemetry-plugin-react-load/package.json
index ebefe1cd1b6..85c0eb9a9eb 100644
--- a/plugins/web/opentelemetry-plugin-react-load/package.json
+++ b/plugins/web/opentelemetry-plugin-react-load/package.json
@@ -48,8 +48,8 @@
   },
   "devDependencies": {
     "@babel/core": "7.14.3",
-    "@opentelemetry/api": "0.20.0",
-    "@opentelemetry/propagator-b3": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
+    "@opentelemetry/propagator-b3": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.3",
     "@types/react": "17.0.9",
@@ -82,15 +82,15 @@
     "webpack-merge": "5.7.3"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0",
+    "@opentelemetry/api": "^0.21.0",
     "react": "^16.13.1 || ^17.0.0"
   },
   "dependencies": {
-    "@opentelemetry/context-zone": "^0.20.0",
-    "@opentelemetry/core": "^0.20.0",
-    "@opentelemetry/semantic-conventions": "^0.20.0",
-    "@opentelemetry/tracing": "^0.20.0",
-    "@opentelemetry/web": "^0.20.0",
+    "@opentelemetry/context-zone": "^0.21.0",
+    "@opentelemetry/core": "^0.21.0",
+    "@opentelemetry/semantic-conventions": "^0.21.0",
+    "@opentelemetry/tracing": "^0.21.0",
+    "@opentelemetry/web": "^0.21.0",
     "shimmer": "^1.2.1"
   }
 }
diff --git a/propagators/opentelemetry-propagator-aws-xray/package.json b/propagators/opentelemetry-propagator-aws-xray/package.json
index a4add3e33c2..7ba734265e8 100644
--- a/propagators/opentelemetry-propagator-aws-xray/package.json
+++ b/propagators/opentelemetry-propagator-aws-xray/package.json
@@ -46,10 +46,10 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
     "@types/mocha": "8.2.2",
     "@types/node": "14.17.2",
     "@types/webpack-env": "1.16.0",
@@ -71,6 +71,6 @@
     "webpack": "4.46.0"
   },
   "dependencies": {
-    "@opentelemetry/core": "^0.20.0"
+    "@opentelemetry/core": "^0.21.0"
   }
 }
diff --git a/propagators/opentelemetry-propagator-grpc-census-binary/package.json b/propagators/opentelemetry-propagator-grpc-census-binary/package.json
index 823d9105c36..e7900a422e2 100644
--- a/propagators/opentelemetry-propagator-grpc-census-binary/package.json
+++ b/propagators/opentelemetry-propagator-grpc-census-binary/package.json
@@ -42,10 +42,10 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
     "@types/mocha": "7.0.2",
     "@types/node": "14.17.2",
     "codecov": "3.8.2",
diff --git a/propagators/opentelemetry-propagator-ot-trace/package.json b/propagators/opentelemetry-propagator-ot-trace/package.json
index e6343614a2b..36f0549ce20 100644
--- a/propagators/opentelemetry-propagator-ot-trace/package.json
+++ b/propagators/opentelemetry-propagator-ot-trace/package.json
@@ -47,10 +47,10 @@
     "access": "public"
   },
   "peerDependencies": {
-    "@opentelemetry/api": "^0.20.0"
+    "@opentelemetry/api": "^0.21.0"
   },
   "devDependencies": {
-    "@opentelemetry/api": "0.20.0",
+    "@opentelemetry/api": "0.21.0",
     "@types/mocha": "8.2.2",
     "@types/node": "14.17.2",
     "@types/webpack-env": "1.16.0",