diff --git a/src/coreclr/jit/optimizer.cpp b/src/coreclr/jit/optimizer.cpp
index 1b028eca78b846..ee576b1bc35964 100644
--- a/src/coreclr/jit/optimizer.cpp
+++ b/src/coreclr/jit/optimizer.cpp
@@ -2479,8 +2479,24 @@ PhaseStatus Compiler::optOptimizePostLayout()
         {
             GenTree* const test = block->lastNode();
             assert(test->OperIsConditionalJump());
-            GenTree* const cond = gtReverseCond(test);
-            assert(cond == test); // Ensure `gtReverseCond` did not create a new node
+
+            if (test->OperIs(GT_JTRUE))
+            {
+                // Flip GT_JTRUE node's conditional operand, and handle any new nodes this may introduce
+                GenTree* const cond    = test->gtGetOp1();
+                GenTree* const newCond = gtReverseCond(cond);
+                if (cond != newCond)
+                {
+                    LIR::AsRange(block).InsertAfter(cond, newCond);
+                    test->AsUnOp()->gtOp1 = newCond;
+                }
+            }
+            else
+            {
+                // gtReverseCond can handle other conditional jumps without introducing a new node
+                GenTree* const cond = gtReverseCond(test);
+                assert(cond == test);
+            }
 
             FlowEdge* const oldTrueEdge  = block->GetTrueEdge();
             FlowEdge* const oldFalseEdge = block->GetFalseEdge();