diff --git a/src/libraries/System.Configuration.ConfigurationManager/src/System/Configuration/ClientConfigPaths.cs b/src/libraries/System.Configuration.ConfigurationManager/src/System/Configuration/ClientConfigPaths.cs
index 583a1330fb530..b6523eeed486e 100644
--- a/src/libraries/System.Configuration.ConfigurationManager/src/System/Configuration/ClientConfigPaths.cs
+++ b/src/libraries/System.Configuration.ConfigurationManager/src/System/Configuration/ClientConfigPaths.cs
@@ -70,7 +70,7 @@ private ClientConfigPaths(string exePath, bool includeUserConfig)
                     // Try to find the native entry point.
                     using (Process currentProcess = Process.GetCurrentProcess())
                     {
-                        ApplicationUri = currentProcess.MainModule.FileName;
+                        ApplicationUri = currentProcess.MainModule?.FileName;
                     }
                 }
             }