diff --git a/README.md b/README.md index afb8fef..eda6f0b 100644 --- a/README.md +++ b/README.md @@ -1,11 +1,12 @@ + ## Single Cell Inference of MorphIng Trajectories and their Associated Regulation module SCIMITAR provides a variety of tools to analyze trajectory maps of single-cell measurements. With SCIMITAR you can: * Obtain coarse-grain, (metastable) state and transition representations of your data. This is useful when you want to get a broad sense of how your data is connected. -* Infer full-fledged Gaussian distribution trajectories from single-cell data --- not only will you get cell orderings and estiamted 'pseudotemporal' mean measurements but also pseudo-time-dependant covariance matrices so you can track how your measurements' correlation change across biological progression. +* Infer full-fledged Gaussian distribution trajectories from single-cell data --- not only will you get cell orderings and estimated 'pseudotemporal' mean measurements but also pseudo-time-dependant covariance matrices so you can track how your measurements' correlation change across biological progression. * Obtain uncertainties for a cell's psuedotemporal positioning (due to uncertainty arising from heteroscedastic noise) * Obtain genes that significantly change throughout the progression (i.e. 'progression-associated genes') * Obtain genes that significantly change their correlation structure throughout the progression (i.e. 'progression co-associated genes')