diff --git a/ci/test/00_setup_env_native_fuzz_with_msan.sh b/ci/test/00_setup_env_native_fuzz_with_msan.sh
index e615c63276ec9..36a172e42c9bf 100755
--- a/ci/test/00_setup_env_native_fuzz_with_msan.sh
+++ b/ci/test/00_setup_env_native_fuzz_with_msan.sh
@@ -17,7 +17,7 @@ export PACKAGES="ninja-build"
 # BDB generates false-positives and will be removed in future
 export DEP_OPTS="DEBUG=1 NO_BDB=1 NO_QT=1 CC=clang CXX=clang++ CFLAGS='${MSAN_FLAGS}' CXXFLAGS='${MSAN_AND_LIBCXX_FLAGS}'"
 export GOAL="install"
-export BITCOIN_CONFIG="--enable-fuzz --with-sanitizers=fuzzer,memory --disable-hardening --with-asm=no CPPFLAGS='-DBOOST_MULTI_INDEX_ENABLE_SAFE_MODE'"
+export BITCOIN_CONFIG="--enable-fuzz --with-sanitizers=fuzzer,memory --disable-hardening CPPFLAGS='-DBOOST_MULTI_INDEX_ENABLE_SAFE_MODE'"
 export USE_MEMORY_SANITIZER="true"
 export RUN_UNIT_TESTS="false"
 export RUN_FUNCTIONAL_TESTS="false"
diff --git a/ci/test/00_setup_env_native_msan.sh b/ci/test/00_setup_env_native_msan.sh
index b26b86cb2ffe6..431e4aba49158 100755
--- a/ci/test/00_setup_env_native_msan.sh
+++ b/ci/test/00_setup_env_native_msan.sh
@@ -17,7 +17,7 @@ export PACKAGES="ninja-build"
 # BDB generates false-positives and will be removed in future
 export DEP_OPTS="DEBUG=1 NO_BDB=1 NO_QT=1 CC=clang CXX=clang++ CFLAGS='${MSAN_FLAGS}' CXXFLAGS='${MSAN_AND_LIBCXX_FLAGS}'"
 export GOAL="install"
-export BITCOIN_CONFIG="--with-sanitizers=memory --disable-hardening --with-asm=no"
+export BITCOIN_CONFIG="--with-sanitizers=memory --disable-hardening"
 export USE_MEMORY_SANITIZER="true"
 export RUN_FUNCTIONAL_TESTS="false"
 export CCACHE_MAXSIZE=250M