diff --git a/modules/core/04-channel/v2/client/cli/cli.go b/modules/core/04-channel/v2/client/cli/cli.go
index 5c5a897b0f9..c725fe8ee12 100644
--- a/modules/core/04-channel/v2/client/cli/cli.go
+++ b/modules/core/04-channel/v2/client/cli/cli.go
@@ -36,7 +36,8 @@ func NewTxCmd() *cobra.Command {
 	}
 
 	txCmd.AddCommand(
-		newProvideCounterpartyCmd(),
+		newCreateChannelTxCmd(),
+		newProvideCounterpartyTxCmd(),
 	)
 
 	return txCmd
diff --git a/modules/core/04-channel/v2/client/cli/tx.go b/modules/core/04-channel/v2/client/cli/tx.go
index 9ff268d4843..418f01815e7 100644
--- a/modules/core/04-channel/v2/client/cli/tx.go
+++ b/modules/core/04-channel/v2/client/cli/tx.go
@@ -1,7 +1,9 @@
 package cli
 
 import (
+	"encoding/hex"
 	"fmt"
+	"strings"
 
 	"github.com/spf13/cobra"
 
@@ -11,11 +13,42 @@ import (
 	"github.com/cosmos/cosmos-sdk/version"
 
 	"github.com/cosmos/ibc-go/v9/modules/core/04-channel/v2/types"
+	commitmenttypesv2 "github.com/cosmos/ibc-go/v9/modules/core/23-commitment/types/v2"
 	"github.com/cosmos/ibc-go/v9/modules/core/exported"
 )
 
+// newCreateChannelTxCmd defines the command to create an IBC channel/v2.
+func newCreateChannelTxCmd() *cobra.Command {
+	cmd := &cobra.Command{
+		Use:     "create-channel [client-identifier] [merkle-path-prefix]",
+		Args:    cobra.ExactArgs(2),
+		Short:   "create an IBC channel/v2",
+		Long:    `Creates an IBC channel/v2 using the client identifier representing the counterparty chain and the hex-encoded merkle path prefix under which the counterparty stores packet flow information.`,
+		Example: fmt.Sprintf("%s tx %s %s create-channel 07-tendermint-0 696263,657572656b61", version.AppName, exported.ModuleName, types.SubModuleName),
+		RunE: func(cmd *cobra.Command, args []string) error {
+			clientCtx, err := client.GetClientTxContext(cmd)
+			if err != nil {
+				return err
+			}
+
+			clientID := args[0]
+			merklePathPrefix, err := parseMerklePathPrefix(args[2])
+			if err != nil {
+				return err
+			}
+
+			msg := types.NewMsgCreateChannel(clientID, merklePathPrefix, clientCtx.GetFromAddress().String())
+
+			return tx.GenerateOrBroadcastTxCLI(clientCtx, cmd.Flags(), msg)
+		},
+	}
+
+	flags.AddTxFlagsToCmd(cmd)
+	return cmd
+}
+
 // newProvideCounterpartyCmd defines the command to provide the counterparty channel identifier to an IBC channel.
-func newProvideCounterpartyCmd() *cobra.Command {
+func newProvideCounterpartyTxCmd() *cobra.Command {
 	cmd := &cobra.Command{
 		Use:     "provide-counterparty [channel-identifier] [counterparty-channel-identifier]",
 		Args:    cobra.ExactArgs(2),
@@ -43,3 +76,18 @@ func newProvideCounterpartyCmd() *cobra.Command {
 	flags.AddTxFlagsToCmd(cmd)
 	return cmd
 }
+
+// parseMerklePathPrefix parses a comma-separated list of hex-encoded strings into a MerklePath.
+func parseMerklePathPrefix(merklePathPrefixString string) (commitmenttypesv2.MerklePath, error) {
+	var keyPath [][]byte
+	hexPrefixes := strings.Split(merklePathPrefixString, ",")
+	for _, hexPrefix := range hexPrefixes {
+		prefix, err := hex.DecodeString(hexPrefix)
+		if err != nil {
+			return commitmenttypesv2.MerklePath{}, fmt.Errorf("invalid hex merkle path prefix: %w", err)
+		}
+		keyPath = append(keyPath, prefix)
+	}
+
+	return commitmenttypesv2.MerklePath{KeyPath: keyPath}, nil
+}