diff --git a/CHANGELOG.md b/CHANGELOG.md
index b1c127bc3197..787ddee263c3 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -114,6 +114,7 @@ Ref: https://keepachangelog.com/en/1.0.0/
 
 ### Improvements
 
+* [\#10439](https://github.com/cosmos/cosmos-sdk/pull/10439) Check error for `RegisterQueryHandlerClient` in all modules `RegisterGRPCGatewayRoutes`.
 * [\#9780](https://github.com/cosmos/cosmos-sdk/pull/9780) Remove gogoproto `moretags` YAML annotations and add `sigs.k8s.io/yaml` for YAML marshalling.
 * (x/bank) [\#10134](https://github.com/cosmos/cosmos-sdk/pull/10134) Add `HasDenomMetadata` function to bank `Keeper` to check if a client coin denom metadata exists in state.
 * (types) [\#10076](https://github.com/cosmos/cosmos-sdk/pull/10076) Significantly speedup and lower allocations for `Coins.String()`.
diff --git a/x/authz/module/module.go b/x/authz/module/module.go
index b1afdc06e12f..5e779244aa48 100644
--- a/x/authz/module/module.go
+++ b/x/authz/module/module.go
@@ -76,7 +76,9 @@ func (AppModuleBasic) RegisterRESTRoutes(_ sdkclient.Context, _ *mux.Router) {}
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the authz module.
 func (a AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx sdkclient.Context, mux *runtime.ServeMux) {
-	authz.RegisterQueryHandlerClient(context.Background(), mux, authz.NewQueryClient(clientCtx))
+	if err := authz.RegisterQueryHandlerClient(context.Background(), mux, authz.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetQueryCmd returns the cli query commands for the authz module
diff --git a/x/bank/module.go b/x/bank/module.go
index 62038da8b7b8..169f5b26ac4b 100644
--- a/x/bank/module.go
+++ b/x/bank/module.go
@@ -68,7 +68,9 @@ func (AppModuleBasic) RegisterRESTRoutes(_ client.Context, _ *mux.Router) {}
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the bank module.
 func (AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx client.Context, mux *runtime.ServeMux) {
-	types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx))
+	if err := types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetTxCmd returns the root tx command for the bank module.
diff --git a/x/distribution/module.go b/x/distribution/module.go
index 09232331e333..13cf674e3be0 100644
--- a/x/distribution/module.go
+++ b/x/distribution/module.go
@@ -8,7 +8,6 @@ import (
 
 	"github.com/gorilla/mux"
 	"github.com/grpc-ecosystem/grpc-gateway/runtime"
-
 	"github.com/spf13/cobra"
 	abci "github.com/tendermint/tendermint/abci/types"
 
@@ -69,7 +68,9 @@ func (AppModuleBasic) RegisterRESTRoutes(_ sdkclient.Context, _ *mux.Router) {}
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the distribution module.
 func (AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx sdkclient.Context, mux *runtime.ServeMux) {
-	types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx))
+	if err := types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetTxCmd returns the root tx command for the distribution module.
diff --git a/x/evidence/module.go b/x/evidence/module.go
index cb6a358c164a..2d65ef8ead8a 100644
--- a/x/evidence/module.go
+++ b/x/evidence/module.go
@@ -8,9 +8,7 @@ import (
 
 	"github.com/gorilla/mux"
 	"github.com/grpc-ecosystem/grpc-gateway/runtime"
-
 	"github.com/spf13/cobra"
-
 	abci "github.com/tendermint/tendermint/abci/types"
 
 	"github.com/cosmos/cosmos-sdk/client"
@@ -80,7 +78,9 @@ func (AppModuleBasic) RegisterRESTRoutes(_ client.Context, _ *mux.Router) {}
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the evidence module.
 func (a AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx client.Context, mux *runtime.ServeMux) {
-	types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx))
+	if err := types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetTxCmd returns the evidence module's root tx command.
diff --git a/x/feegrant/module/module.go b/x/feegrant/module/module.go
index df6089b40fba..44107bc733da 100644
--- a/x/feegrant/module/module.go
+++ b/x/feegrant/module/module.go
@@ -8,7 +8,6 @@ import (
 	"github.com/gorilla/mux"
 	"github.com/grpc-ecosystem/grpc-gateway/runtime"
 	"github.com/spf13/cobra"
-
 	abci "github.com/tendermint/tendermint/abci/types"
 
 	sdkclient "github.com/cosmos/cosmos-sdk/client"
@@ -87,7 +86,9 @@ func (AppModuleBasic) RegisterRESTRoutes(clientCtx sdkclient.Context, rtr *mux.R
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the feegrant module.
 func (AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx sdkclient.Context, mux *runtime.ServeMux) {
-	feegrant.RegisterQueryHandlerClient(context.Background(), mux, feegrant.NewQueryClient(clientCtx))
+	if err := feegrant.RegisterQueryHandlerClient(context.Background(), mux, feegrant.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetTxCmd returns the root tx command for the feegrant module.
diff --git a/x/gov/module.go b/x/gov/module.go
index 659e5559275c..311ef7ffa0df 100644
--- a/x/gov/module.go
+++ b/x/gov/module.go
@@ -78,7 +78,9 @@ func (a AppModuleBasic) RegisterRESTRoutes(clientCtx client.Context, rtr *mux.Ro
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the gov module.
 func (a AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx client.Context, mux *runtime.ServeMux) {
-	types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx))
+	if err := types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetTxCmd returns the root tx command for the gov module.
diff --git a/x/mint/module.go b/x/mint/module.go
index e923790dc0fb..27fb7beba05c 100644
--- a/x/mint/module.go
+++ b/x/mint/module.go
@@ -70,8 +70,9 @@ func (AppModuleBasic) RegisterRESTRoutes(clientCtx client.Context, rtr *mux.Rout
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the mint module.
 func (AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx client.Context, mux *runtime.ServeMux) {
-	types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx))
-
+	if err := types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetTxCmd returns no root tx command for the mint module.
diff --git a/x/params/module.go b/x/params/module.go
index e27eaf44a2ef..f17ab2199d44 100644
--- a/x/params/module.go
+++ b/x/params/module.go
@@ -7,7 +7,6 @@ import (
 
 	"github.com/gorilla/mux"
 	"github.com/grpc-ecosystem/grpc-gateway/runtime"
-
 	"github.com/spf13/cobra"
 	abci "github.com/tendermint/tendermint/abci/types"
 
@@ -58,7 +57,9 @@ func (AppModuleBasic) RegisterRESTRoutes(clientCtx client.Context, rtr *mux.Rout
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the params module.
 func (AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx client.Context, mux *runtime.ServeMux) {
-	proposal.RegisterQueryHandlerClient(context.Background(), mux, proposal.NewQueryClient(clientCtx))
+	if err := proposal.RegisterQueryHandlerClient(context.Background(), mux, proposal.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetTxCmd returns no root tx command for the params module.
diff --git a/x/slashing/module.go b/x/slashing/module.go
index 68c3c2919cdd..cf51b57066ad 100644
--- a/x/slashing/module.go
+++ b/x/slashing/module.go
@@ -8,9 +8,7 @@ import (
 
 	"github.com/gorilla/mux"
 	"github.com/grpc-ecosystem/grpc-gateway/runtime"
-
 	"github.com/spf13/cobra"
-
 	abci "github.com/tendermint/tendermint/abci/types"
 
 	"github.com/cosmos/cosmos-sdk/client"
@@ -77,7 +75,9 @@ func (AppModuleBasic) RegisterRESTRoutes(clientCtx client.Context, rtr *mux.Rout
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the slashig module.
 func (AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx client.Context, mux *runtime.ServeMux) {
-	types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx))
+	if err := types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetTxCmd returns the root tx command for the slashing module.
diff --git a/x/staking/module.go b/x/staking/module.go
index 6dfd0c67f8a9..ffe1e69fdd70 100644
--- a/x/staking/module.go
+++ b/x/staking/module.go
@@ -8,7 +8,6 @@ import (
 
 	"github.com/gorilla/mux"
 	"github.com/grpc-ecosystem/grpc-gateway/runtime"
-
 	"github.com/spf13/cobra"
 	abci "github.com/tendermint/tendermint/abci/types"
 
@@ -79,7 +78,9 @@ func (AppModuleBasic) RegisterRESTRoutes(clientCtx client.Context, rtr *mux.Rout
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the staking module.
 func (AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx client.Context, mux *runtime.ServeMux) {
-	types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx))
+	if err := types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetTxCmd returns the root tx command for the staking module.
diff --git a/x/upgrade/module.go b/x/upgrade/module.go
index 00e966912d13..ed4b6e0ed9f3 100644
--- a/x/upgrade/module.go
+++ b/x/upgrade/module.go
@@ -48,7 +48,9 @@ func (AppModuleBasic) RegisterRESTRoutes(clientCtx client.Context, rtr *mux.Rout
 
 // RegisterGRPCGatewayRoutes registers the gRPC Gateway routes for the upgrade module.
 func (AppModuleBasic) RegisterGRPCGatewayRoutes(clientCtx client.Context, mux *runtime.ServeMux) {
-	types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx))
+	if err := types.RegisterQueryHandlerClient(context.Background(), mux, types.NewQueryClient(clientCtx)); err != nil {
+		panic(err)
+	}
 }
 
 // GetQueryCmd returns the cli query commands for this module