diff --git a/pkg/ccl/followerreadsccl/followerreads.go b/pkg/ccl/followerreadsccl/followerreads.go
index 33ab16ccabef..4ae7fd3efed6 100644
--- a/pkg/ccl/followerreadsccl/followerreads.go
+++ b/pkg/ccl/followerreadsccl/followerreads.go
@@ -93,7 +93,7 @@ func canUseFollowerRead(clusterID uuid.UUID, st *cluster.Settings, ts hlc.Timest
 // canSendToFollower implements the logic for checking whether a batch request
 // may be sent to a follower.
 func canSendToFollower(clusterID uuid.UUID, st *cluster.Settings, ba roachpb.BatchRequest) bool {
-	return ba.IsReadOnly() && ba.Txn != nil &&
+	return ba.IsReadOnly() && ba.Txn != nil && !ba.Txn.IsWriting() &&
 		canUseFollowerRead(clusterID, st, ba.Txn.OrigTimestamp)
 }
 
diff --git a/pkg/ccl/followerreadsccl/followerreads_test.go b/pkg/ccl/followerreadsccl/followerreads_test.go
index 4e3b6e93303a..44d6bde6c560 100644
--- a/pkg/ccl/followerreadsccl/followerreads_test.go
+++ b/pkg/ccl/followerreadsccl/followerreads_test.go
@@ -22,6 +22,7 @@ import (
 	"github.com/cockroachdb/cockroach/pkg/settings/cluster"
 	"github.com/cockroachdb/cockroach/pkg/sql/distsqlplan/replicaoracle"
 	"github.com/cockroachdb/cockroach/pkg/storage"
+	"github.com/cockroachdb/cockroach/pkg/storage/engine/enginepb"
 	"github.com/cockroachdb/cockroach/pkg/testutils"
 	"github.com/cockroachdb/cockroach/pkg/util/hlc"
 	"github.com/cockroachdb/cockroach/pkg/util/leaktest"
@@ -79,6 +80,16 @@ func TestCanSendToFollower(t *testing.T) {
 	if !canSendToFollower(uuid.MakeV4(), st, roOld) {
 		t.Fatalf("should be able to send an old ro batch to a follower")
 	}
+	roRWTxnOld := roachpb.BatchRequest{Header: roachpb.Header{
+		Txn: &roachpb.Transaction{
+			TxnMeta:       enginepb.TxnMeta{Key: []byte("key")},
+			OrigTimestamp: old,
+		},
+	}}
+	roRWTxnOld.Add(&roachpb.GetRequest{})
+	if canSendToFollower(uuid.MakeV4(), st, roRWTxnOld) {
+		t.Fatalf("should not be able to send a ro request from a rw txn to a follower")
+	}
 	storage.FollowerReadsEnabled.Override(&st.SV, false)
 	if canSendToFollower(uuid.MakeV4(), st, roOld) {
 		t.Fatalf("should not be able to send an old ro batch to a follower when follower reads are disabled")
diff --git a/pkg/storage/closed_timestamp_test.go b/pkg/storage/closed_timestamp_test.go
index 174d16105152..0b167dd11639 100644
--- a/pkg/storage/closed_timestamp_test.go
+++ b/pkg/storage/closed_timestamp_test.go
@@ -19,6 +19,7 @@ import (
 	gosql "database/sql"
 	"fmt"
 	"math/rand"
+	"sync/atomic"
 	"testing"
 	"time"
 
@@ -265,6 +266,60 @@ func getTableID(db *gosql.DB, dbName, tableName string) (tableID sqlbase.ID, err
 	return
 }
 
+func TestClosedTimestampCantServeForWritingTransaction(t *testing.T) {
+	defer leaktest.AfterTest(t)()
+
+	if util.RaceEnabled {
+		// Limiting how long transactions can run does not work
+		// well with race unless we're extremely lenient, which
+		// drives up the test duration.
+		t.Skip("skipping under race")
+	}
+
+	ctx := context.Background()
+	tc, db0, desc, repls := setupTestClusterForClosedTimestampTesting(ctx, t)
+	defer tc.Stopper().Stop(ctx)
+
+	if _, err := db0.Exec(`INSERT INTO cttest.kv VALUES(1, $1)`, "foo"); err != nil {
+		t.Fatal(err)
+	}
+
+	// Verify that we can serve a follower read at a timestamp. Wait if necessary.
+	ts := hlc.Timestamp{WallTime: timeutil.Now().UnixNano()}
+	testutils.SucceedsSoon(t, func() error {
+		return verifyCanReadFromAllRepls(ctx, t, desc, ts, repls, expectRows(1))
+	})
+
+	// Create a read-only batch and attach a read-write transaction.
+	rwTxn := roachpb.MakeTransaction("test", []byte("key"), roachpb.NormalUserPriority, ts, 0)
+	baRead := makeReadBatchRequestForDesc(desc, ts)
+	baRead.Txn = &rwTxn
+
+	// Send the request to all three replicas. One should succeed and
+	// the other two should return NotLeaseHolderErrors.
+	g, ctx := errgroup.WithContext(ctx)
+	var notLeaseholderErrs int64
+	for i := range repls {
+		repl := repls[i]
+		g.Go(func() (err error) {
+			if _, pErr := repl.Send(ctx, baRead); pErr != nil {
+				if _, ok := pErr.GetDetail().(*roachpb.NotLeaseHolderError); ok {
+					atomic.AddInt64(&notLeaseholderErrs, 1)
+					return nil
+				}
+				return pErr.GetDetail()
+			}
+			return nil
+		})
+	}
+	if err := g.Wait(); err != nil {
+		t.Fatal(err)
+	}
+	if a, e := notLeaseholderErrs, int64(2); a != e {
+		t.Fatalf("expected %d NotLeaseHolderError; found %d", e, a)
+	}
+}
+
 // Every 0.1s=100ms, try close out a timestamp ~300ms in the past.
 // We don't want to be more aggressive than that since it's also
 // a limit on how long transactions can run.
@@ -451,17 +506,15 @@ func verifyCanReadFromAllRepls(
 	g, ctx := errgroup.WithContext(ctx)
 	for i := range repls {
 		repl := repls[i]
-		func(r *storage.Replica) {
-			g.Go(func() (err error) {
-				var shouldRetry bool
-				for r := retry.StartWithCtx(ctx, retryOptions); r.Next(); <-r.NextCh() {
-					if err, shouldRetry = f(repl.Send(ctx, baRead)); !shouldRetry {
-						return err
-					}
+		g.Go(func() (err error) {
+			var shouldRetry bool
+			for r := retry.StartWithCtx(ctx, retryOptions); r.Next(); <-r.NextCh() {
+				if err, shouldRetry = f(repl.Send(ctx, baRead)); !shouldRetry {
+					return err
 				}
-				return err
-			})
-		}(repls[i])
+			}
+			return err
+		})
 	}
 	return g.Wait()
 }
diff --git a/pkg/storage/replica_follower_read.go b/pkg/storage/replica_follower_read.go
index 7ec03d95f927..ab1dfd1f682c 100644
--- a/pkg/storage/replica_follower_read.go
+++ b/pkg/storage/replica_follower_read.go
@@ -43,8 +43,9 @@ func (r *Replica) canServeFollowerRead(
 ) *roachpb.Error {
 	canServeFollowerRead := false
 	if lErr, ok := pErr.GetDetail().(*roachpb.NotLeaseHolderError); ok &&
+		lErr.LeaseHolder != nil && lErr.Lease.Type() == roachpb.LeaseEpoch &&
 		FollowerReadsEnabled.Get(&r.store.cfg.Settings.SV) &&
-		lErr.LeaseHolder != nil && lErr.Lease.Type() == roachpb.LeaseEpoch {
+		(ba.Txn == nil || !ba.Txn.IsWriting()) {
 
 		canServeFollowerRead = !r.maxClosed(ctx).Less(ba.Timestamp)
 		if !canServeFollowerRead {