diff --git a/pkg/cmd/roachtest/tests/npgsql_blocklist.go b/pkg/cmd/roachtest/tests/npgsql_blocklist.go
index 27ed5162c840..919ae9a42c11 100644
--- a/pkg/cmd/roachtest/tests/npgsql_blocklist.go
+++ b/pkg/cmd/roachtest/tests/npgsql_blocklist.go
@@ -64,6 +64,7 @@ var npgsqlBlocklist = blocklist{
 	`Npgsql.Tests.CommandTests(Multiplexing).Multiple_statements_with_dependencies`:                                                               "unknown",
 	`Npgsql.Tests.CommandTests(Multiplexing).Non_standards_conforming_strings`:                                                                    "unknown",
 	`Npgsql.Tests.CommandTests(Multiplexing).Positional_parameters_are_not_supported_with_legacy_batching`:                                        "unknown",
+	`Npgsql.Tests.CommandTests(Multiplexing).Reuse_command_with_different_parameter_placeholder_types`:                                            "flaky",
 	`Npgsql.Tests.CommandTests(NonMultiplexing).Cursor_statement`:                                                                                 "unknown",
 	`Npgsql.Tests.CommandTests(NonMultiplexing).ExecuteNonQuery_Throws_PostgresException(False)`:                                                  "unknown",
 	`Npgsql.Tests.CommandTests(NonMultiplexing).ExecuteNonQuery_Throws_PostgresException(True)`:                                                   "unknown",
@@ -716,9 +717,12 @@ var npgsqlBlocklist = blocklist{
 var npgsqlIgnoreList = blocklist{
 	`Npgsql.Tests.CommandTests(Multiplexing).Cursor_move_RecordsAffected `:                            "flaky",
 	`Npgsql.Tests.CommandTests(Multiplexing).QueryNonQuery`:                                           "flaky",
+	`Npgsql.Tests.CommandTests(Multiplexing).Same_command_different_param_instances`:                  "flaky",
+	`Npgsql.Tests.CommandTests(Multiplexing).Same_command_different_param_values`:                     "flaky",
 	`Npgsql.Tests.CommandTests(Multiplexing).SingleNonQuery`:                                          "flaky",
 	`Npgsql.Tests.CommandTests(Multiplexing).SingleQuery`:                                             "flaky",
 	`Npgsql.Tests.CommandTests(Multiplexing).Statement_mapped_output_parameters(Default)`:             "flaky",
+	`Npgsql.Tests.CommandTests(Multiplexing).TableDirect`:                                             "flaky",
 	`Npgsql.Tests.CommandTests(Multiplexing).Use_across_connection_change(NotPrepared)`:               "flaky",
 	`Npgsql.Tests.CommandTests(NonMultiplexing).Cached_command_clears_parameters_placeholder_type`:    "flaky",
 	`Npgsql.Tests.CommandTests(NonMultiplexing).CloseConnection_with_exception`:                       "flaky",
@@ -771,4 +775,6 @@ var npgsqlIgnoreList = blocklist{
 	`Npgsql.Tests.TaskTimeoutAndCancellationTest.DelayedFaultedTaskCancellation("TimeoutOnly")`:       "flaky",
 	`Npgsql.Tests.TransactionTests(Multiplexing).Failed_transaction_on_close_with_custom_timeout`:     "flaky",
 	`Npgsql.Tests.TransactionTests(NonMultiplexing).CommitAsync(Prepared)`:                            "flaky",
+	`Npgsql.Tests.TransactionTests(NonMultiplexing).Rollback(Prepared)`:                               "flaky",
+	`Npgsql.Tests.TransactionTests(NonMultiplexing).RollbackAsync(NotPrepared)`:                       "flaky",
 }