diff --git a/vdt-integer-overflow.patch b/vdt-integer-overflow.patch
new file mode 100644
index 00000000000..9d5b291e01c
--- /dev/null
+++ b/vdt-integer-overflow.patch
@@ -0,0 +1,14 @@
+diff --git a/include/sincos.h b/include/sincos.h
+index 563ae93..2ca2855 100644
+--- a/include/sincos.h
++++ b/include/sincos.h
+@@ -204,6 +204,9 @@ inline void fast_sincosf_m45_45( const float x, float & s, float &c ) {
+ } // end details namespace
+ 
+ /// Single precision sincos
++#ifdef CMS_UNDEFINED_SANITIZER
++__attribute__((no_sanitize("signed-integer-overflow")))
++#endif
+ inline void fast_sincosf( const float xx, float & s, float &c ) {
+ 	
+ 
diff --git a/vdt.spec b/vdt.spec
index b6405575687..9dfe470639e 100644
--- a/vdt.spec
+++ b/vdt.spec
@@ -1,7 +1,8 @@
 ### RPM cms vdt 0.4.3
 
-Source: https://github.com/dpiparo/%{n}/archive/v%{realversion}.tar.gz 
-
+Source: https://github.com/dpiparo/%{n}/archive/v%{realversion}.tar.gz
+# To avoid UBSan runtime errors about signed integer overflow: cms-sw/cmssw#46417
+Patch0: vdt-integer-overflow
 BuildRequires: cmake python3
 
 
@@ -9,6 +10,7 @@ BuildRequires: cmake python3
 
 %prep
 %setup -q -n %{n}-%{realversion}
+%patch0 -p1
 
 %build
 cmake . \