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genome size larger than estimate genome size #731

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yaradua opened this issue Nov 29, 2024 · 1 comment
Open

genome size larger than estimate genome size #731

yaradua opened this issue Nov 29, 2024 · 1 comment

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@yaradua
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yaradua commented Nov 29, 2024

Hi,

Thank you for developing the program. I am trying to assemble a genome with an estimated size of 1.47GB. Hifiasm gives me an assembly with a size of 7.5GB. I have tried several parameters (-s 0.3 and --hom-cov) but am getting the same result. Can you please advise on how to solve this issue?

Thank you.
Samaila Yaradua

@yaradua
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yaradua commented Dec 13, 2024

Hello,

Your input will be highly appreciated. I am still yet to get a good assembly, I have tried several parameters, can you please help. The genome has a heterozygosity of 6.13% with a lot of repetition.

Thank you in advance.
Samaila

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