diff --git a/packages/carbon-web-components/tools/get-rollup-config.js b/packages/carbon-web-components/tools/get-rollup-config.js
index 6db937844d4..f11c495a585 100644
--- a/packages/carbon-web-components/tools/get-rollup-config.js
+++ b/packages/carbon-web-components/tools/get-rollup-config.js
@@ -176,6 +176,7 @@ function getRollupConfig({
       }),
       replace({
         'process.env.NODE_ENV': JSON.stringify(mode),
+        preventAssignment: true,
       }),
       ...(mode === 'development'
         ? [license(licenseOptions)]