diff --git a/packages/api/schema/stryker-core.json b/packages/api/schema/stryker-core.json
index 72f0b358cc..8b241b13d5 100644
--- a/packages/api/schema/stryker-core.json
+++ b/packages/api/schema/stryker-core.json
@@ -754,9 +754,14 @@
             "description": "Replace ```\"\"``` with ```\"Stryker was here!\"```."
           },
           {
-            "const": "Interpolation",
-            "title": "InterpolationMutator",
+            "const": "EmptyInterpolation",
+            "title": "EmptyInterpolation",
             "description": "Replace ```s\"foo ${bar}\"``` with ```s\"\"```."
+          },
+          {
+            "const": "FillInterpolation",
+            "title": "FillInterpolation",
+            "description": "Replace ```s\"\"``` with ```s\"Stryker was here!\"```."
           }
         ]
       }
diff --git a/packages/instrumenter/src/mutators/mutation-level-options.ts b/packages/instrumenter/src/mutators/mutation-level-options.ts
index 8da2c93238..09dfaf59c2 100644
--- a/packages/instrumenter/src/mutators/mutation-level-options.ts
+++ b/packages/instrumenter/src/mutators/mutation-level-options.ts
@@ -3,3 +3,4 @@ import { MutationLevel } from '@stryker-mutator/api/core';
 export interface RunLevelOptions {
   runLevel?: MutationLevel;
 }
+export type MutationOperator = Record<string, { replacementOperator: any; mutatorName: string }>;
diff --git a/packages/instrumenter/src/mutators/string-literal-mutator.ts b/packages/instrumenter/src/mutators/string-literal-mutator.ts
index 9b3dc4c03f..2b66792a1d 100644
--- a/packages/instrumenter/src/mutators/string-literal-mutator.ts
+++ b/packages/instrumenter/src/mutators/string-literal-mutator.ts
@@ -1,19 +1,43 @@
 import babel, { type NodePath } from '@babel/core';
 
 import { NodeMutator } from './node-mutator.js';
+import { MutationOperator } from './mutation-level-options.js';
 
 const { types } = babel;
 
+const operators: MutationOperator = {
+  FillString: { replacementOperator: types.stringLiteral('Stryker was here!'), mutatorName: 'FillString' },
+  EmptyString: { replacementOperator: types.stringLiteral(''), mutatorName: 'EmptyString' },
+  EmptyInterpolation: { replacementOperator: types.templateLiteral([types.templateElement({ raw: '' })], []), mutatorName: 'EmptyInterpolation' },
+  FillInterpolation: {
+    replacementOperator: types.templateLiteral([types.templateElement({ raw: 'Stryker was here!' })], []),
+    mutatorName: 'FillInterpolation',
+  },
+};
+
 export const stringLiteralMutator: NodeMutator = {
   name: 'StringLiteral',
 
-  *mutate(path) {
+  *mutate(path, operations: string[] | undefined) {
     if (path.isTemplateLiteral()) {
-      const replacement = path.node.quasis.length === 1 && path.node.quasis[0].value.raw.length === 0 ? 'Stryker was here!' : '';
-      yield types.templateLiteral([types.templateElement({ raw: replacement })], []);
+      const stringIsEmpty = path.node.quasis.length === 1 && path.node.quasis[0].value.raw.length === 0;
+      if (
+        operations === undefined ||
+        (stringIsEmpty && operations.includes(operators.FillInterpolation.mutatorName)) ||
+        (!stringIsEmpty && operations.includes(operators.EmptyInterpolation.mutatorName))
+      ) {
+        yield stringIsEmpty ? operators.FillInterpolation.replacementOperator : operators.EmptyInterpolation.replacementOperator;
+      }
     }
     if (path.isStringLiteral() && isValidParent(path)) {
-      yield types.stringLiteral(path.node.value.length === 0 ? 'Stryker was here!' : '');
+      const stringIsEmpty = path.node.value.length === 0;
+      if (
+        operations === undefined ||
+        (stringIsEmpty && operations.includes(operators.FillString.mutatorName)) ||
+        (!stringIsEmpty && operations.includes(operators.EmptyString.mutatorName))
+      ) {
+        yield stringIsEmpty ? operators.FillString.replacementOperator : operators.EmptyString.replacementOperator;
+      }
     }
   },
 };
diff --git a/packages/instrumenter/test/unit/mutators/string-literal-mutator.spec.ts b/packages/instrumenter/test/unit/mutators/string-literal-mutator.spec.ts
index fd12ec05e3..af720fc834 100644
--- a/packages/instrumenter/test/unit/mutators/string-literal-mutator.spec.ts
+++ b/packages/instrumenter/test/unit/mutators/string-literal-mutator.spec.ts
@@ -1,6 +1,6 @@
 import { expect } from 'chai';
 
-import { expectJSMutation } from '../../helpers/expect-mutation.js';
+import { expectJSMutation, expectJSMutationWithLevel } from '../../helpers/expect-mutation.js';
 import { stringLiteralMutator as sut } from '../../../src/mutators/string-literal-mutator.js';
 
 describe(sut.name, () => {
@@ -112,4 +112,30 @@ describe(sut.name, () => {
       expectJSMutation(sut, '<Record class="row" />');
     });
   });
+
+  describe('mutation level', () => {
+    it('should only mutate EmptyString and EmptyInterpolation from all possible mutations', () => {
+      expectJSMutationWithLevel(
+        sut,
+        ['EmptyString', 'EmptyInterpolation'],
+        'const bar = "bar"; const foo = `name: ${level_name}`; const emptyString=""; const emptyInterp=``',
+        'const bar = ""; const foo = `name: ${level_name}`; const emptyString=""; const emptyInterp=``', // empties string
+        'const bar = "bar"; const foo = ``; const emptyString=""; const emptyInterp=``', // empties interpolation
+      );
+    });
+    it('should block the mutators', () => {
+      expectJSMutationWithLevel(sut, [], 'const bar = "bar"; const foo = `name: ${level_name}`; const emptyString=""; const emptyInterp=``');
+    });
+    it('should mutate everything', () => {
+      expectJSMutationWithLevel(
+        sut,
+        undefined,
+        'const bar = "bar"; const foo = `name: ${level_name}`; const emptyString=""; const emptyInterp=``',
+        'const bar = ""; const foo = `name: ${level_name}`; const emptyString=""; const emptyInterp=``', // empties string literal
+        'const bar = "bar"; const foo = ``; const emptyString=""; const emptyInterp=``', // empties interpolation
+        'const bar = "bar"; const foo = `name: ${level_name}`; const emptyString="Stryker was here!"; const emptyInterp=``', // fills string literal
+        'const bar = "bar"; const foo = `name: ${level_name}`; const emptyString=""; const emptyInterp=`Stryker was here!`', // fills interpolation
+      );
+    });
+  });
 });
diff --git a/testing-project/stryker.conf.json b/testing-project/stryker.conf.json
index 7ed58556ee..bb7537398e 100644
--- a/testing-project/stryker.conf.json
+++ b/testing-project/stryker.conf.json
@@ -20,6 +20,7 @@
       "name": "default",
       "ArithmeticOperator": ["+To-", "-To+", "*To/"],
       "ArrayDeclaration": ["EmptyArray", "FilledArray", "FilledArrayConstructor"],
+      "StringLiteral": ["EmptyString", "FillString", "EmptyInterpolation", "FillInterpolation"]
       "AssignmentOperator": ["-=To+=", "<<=To>>=", "&&=To||="],
       "BooleanLiteral": ["TrueToFalse", "RemoveNegation"]
     },