diff --git a/Dockerfile b/Dockerfile
index d90dc5f8..39e4b528 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -1,4 +1,4 @@
-FROM quay.io/broadinstitute/viral-core:2.0.18
+FROM quay.io/broadinstitute/viral-core:2.0.21
 
 LABEL maintainer "viral-ngs@broadinstitute.org"