diff --git a/codegen/smithy-aws-typescript-codegen/src/main/resources/software/amazon/smithy/aws/typescript/codegen/endpoints.json b/codegen/smithy-aws-typescript-codegen/src/main/resources/software/amazon/smithy/aws/typescript/codegen/endpoints.json
index c42cecb1b7fa..bf01f88ef9ad 100644
--- a/codegen/smithy-aws-typescript-codegen/src/main/resources/software/amazon/smithy/aws/typescript/codegen/endpoints.json
+++ b/codegen/smithy-aws-typescript-codegen/src/main/resources/software/amazon/smithy/aws/typescript/codegen/endpoints.json
@@ -2731,6 +2731,7 @@
             "ap-southeast-3": {},
             "ap-southeast-4": {},
             "ca-central-1": {},
+            "ca-west-1": {},
             "eu-central-1": {},
             "eu-central-2": {},
             "eu-north-1": {},
@@ -4079,6 +4080,7 @@
             "ap-southeast-3": {},
             "ca-central-1": {},
             "eu-central-1": {},
+            "eu-central-2": {},
             "eu-north-1": {},
             "eu-south-1": {},
             "eu-west-1": {},
@@ -4113,6 +4115,7 @@
               "hostname": "cognito-identity-fips.us-west-2.amazonaws.com"
             },
             "il-central-1": {},
+            "me-central-1": {},
             "me-south-1": {},
             "sa-east-1": {},
             "us-east-1": {
@@ -4161,6 +4164,7 @@
             "ap-southeast-3": {},
             "ca-central-1": {},
             "eu-central-1": {},
+            "eu-central-2": {},
             "eu-north-1": {},
             "eu-south-1": {},
             "eu-west-1": {},
@@ -4195,6 +4199,7 @@
               "hostname": "cognito-idp-fips.us-west-2.amazonaws.com"
             },
             "il-central-1": {},
+            "me-central-1": {},
             "me-south-1": {},
             "sa-east-1": {},
             "us-east-1": {
@@ -4310,9 +4315,23 @@
         "comprehendmedical": {
           "endpoints": {
             "ap-southeast-2": {},
-            "ca-central-1": {},
+            "ca-central-1": {
+              "variants": [
+                {
+                  "hostname": "comprehendmedical-fips.ca-central-1.amazonaws.com",
+                  "tags": ["fips"]
+                }
+              ]
+            },
             "eu-west-1": {},
             "eu-west-2": {},
+            "fips-ca-central-1": {
+              "credentialScope": {
+                "region": "ca-central-1"
+              },
+              "deprecated": true,
+              "hostname": "comprehendmedical-fips.ca-central-1.amazonaws.com"
+            },
             "fips-us-east-1": {
               "credentialScope": {
                 "region": "us-east-1"
@@ -7791,6 +7810,7 @@
             "eu-central-1": {},
             "eu-north-1": {},
             "eu-south-1": {},
+            "eu-south-2": {},
             "eu-west-1": {},
             "eu-west-2": {},
             "eu-west-3": {},
@@ -9757,6 +9777,7 @@
             "ap-northeast-2": {},
             "ap-northeast-3": {},
             "ap-south-1": {},
+            "ap-south-2": {},
             "ap-southeast-1": {},
             "ap-southeast-2": {},
             "ap-southeast-3": {},
@@ -9766,6 +9787,7 @@
             "eu-central-2": {},
             "eu-north-1": {},
             "eu-south-1": {},
+            "eu-south-2": {},
             "eu-west-1": {},
             "eu-west-2": {},
             "eu-west-3": {},
@@ -11269,6 +11291,7 @@
             "ap-southeast-3": {},
             "ap-southeast-4": {},
             "ca-central-1": {},
+            "ca-west-1": {},
             "eu-central-1": {},
             "eu-central-2": {},
             "eu-north-1": {},
@@ -28561,6 +28584,12 @@
             }
           }
         },
+        "signer": {
+          "endpoints": {
+            "us-gov-east-1": {},
+            "us-gov-west-1": {}
+          }
+        },
         "simspaceweaver": {
           "endpoints": {
             "fips-us-gov-east-1": {
@@ -30259,6 +30288,11 @@
             "us-iso-west-1": {}
           }
         },
+        "textract": {
+          "endpoints": {
+            "us-iso-east-1": {}
+          }
+        },
         "transcribe": {
           "defaults": {
             "protocols": ["https"]