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Biomarker-Stomach-HER2.html
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Biomarker-Stomach-HER2.html
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<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html>
<html xmlns="http://www.w3.org/1999/xhtml">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
<title>Stomach HER2</title>
<link rel="stylesheet" type="text/css" href="view.css" media="all">
<script type="text/javascript">
function updateDescription (frm)
{
var Template = ""
if (frm.A05.value !== ""){
Template += "- HER2 IHC (for biopsy): " + frm.A05.value + "\n";
};
if (frm.A06.value !== ""){
Template += " - Score : " + frm.A06.value + "\n";
};
if (frm.A07.value !== ""){
Template += "- HER2 IHC (for excision): " + frm.A07.value + "\n";
};
if (frm.A08.value !== ""){
Template += " - Score : " + frm.A08.value + "\n";
};
if (frm.A09.value !== ""){
Template += "- HER2 DISH : " + frm.A09.value + "\n";
};
if (frm.A10.value !== ""){
Template += " - Number of tumor cell counted : " + frm.A10.value + "\n";
};
if (frm.A11.value !== ""){
Template += " - Average number of HER2 signals (black) per cell : " + frm.A11.value + "\n";
};
if (frm.A12.value !== ""){
Template += " - Average number of CEP17 signals (red) per cell : " + frm.A12.value + "\n";
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if (frm.A13.value !== ""){
Template += " - HER2/CEP17 ratio : " + frm.A13.value + "\n";
};
if (document.getElementById("A14").checked || document.getElementById("A15").checked){
Template += " - Other ISH abnormalities: " + "\n";
}
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Template += frm.A14.value + "\n";
}
if (document.getElementById("A15").checked){
Template += frm.A15.value + "\n";
}
if (frm.A19.value !== ""){
Template += "\n" + "- Additional notes: " + "\n" + " - " + frm.A19.value + "\n";
}
if (frm.A18.value !== ""){
Template += "\n" + "- Fixation time in buffered formalin : " + frm.A18.value + "\n";
}
if (frm.A05.value + frm.A07.value !== ""){
Template += "\n" + "Formalin-fixed paraffin embedded sections were assessed by IHC technique, using Ventana monoclonal HER2/neu (4B5) with Ventana BenchMark ULTRA multimer detection system.";
};
if (frm.A09.value !== ""){
Template += "\n" + "Dual ISH was performed on formalin-fixed paraffin embedded section with the Ventana INFORM HER2 Dual ISH DNA Probe Cocktail Assay on automated system, and examined by pathologist under light microscopy.";
}
frm.holdtext.value = Template;
}
function CopyToClipboard() {
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/* Select the text field */
copyText.select();
/* Copy the text inside the text field */
document.execCommand("copy");
/* Alert the copied text */
alert("Report copied to clipboard");
}
</script>
<script type="text/javascript" src="view.js"></script>
<style>
table, th, td {
border: 1px solid silver;
border-collapse: collapse;
padding: 4px;
}
</style>
</head>
<body>
<img id="top" src="top.png" alt="">
<div id="form_container">
<div class="form_description">
<h2><a href=".\cap\cp-gastric-HER2biomarker17-1001.pdf" target="_blank">
<div class="tooltip">
Stomach HER2 test
<span class="tooltiptext">click to access explanations in the original CAP template</span>
</div>
</a></h2>
</div>
<form>
<p>
<fieldset style="border-color:#e6e6ff;">
<legend> <label class="description">HER2 gene amplification : </label></legend>
<p>
<table border="1">
<col width="40%">
<tr>
<td rowspan="2" valign="top"><label class="description">- <a href=".\cap\StomachHER2_CAP_ACCP_ASCO.pdf" target="_blank">HER2 IHC, biopsy : </a></label>
(> or = 5 cancer cell clusters)
</td>
<td><select class="element select large" ID="A05">
<option value=""></option>
<option value="Cannot be determined">Cannot be determined</option>
<option value="Negative for over-expression">Negative for over-expression</option>
<option value="Equivocal for over-expression">Equivocal for over-expression</option>
<option value="Positive for over-expression">Positive for over-expression</option>
</select></td>
</tr>
<tr>
<td align="right"><label>- Score:</label>
<select class="element select medium" ID="A06">
<option value=""></option>
<option value="0 Negative(No reactivity or no membranous reactivity in any cancer cell)">0 Negative (No reactivity or no membranous reactivity in any cancer cell)</option>
<option value="1 Negative (Cancer cell cluster, > or = 5 cells, with a faint or barely perceptible membranous reactivity irrespective of percentage of cancer cells positive)">1 Negative (Cancer cell cluster, > or = 5 cells) with a faint or barely perceptible membranous reactivity irrespective of percentage of cancer cells positive)</option>
<option value="2 Equivocal (Cancer cell cluster, > or = 5 cells, with a weak to moderate complete, basolateral, or lateral membranous reactivity irrespective of percentage of cancer cells positive)">2 Equivocal (Cancer cell cluster, > or = 5 cells, with a weak to moderate complete, basolateral, or lateral membranous reactivity irrespective of percentage of cancer cells positive)</option>
<option value="3 Positive (Cancer cell cluster, > or = 5 cells, with a strong complete basolateral, or lateral membranous reactivity irrespective of percentage of cancer cells positive)">3 Positive (Cancer cell cluster, > or = 5 cells, with a strong complete basolateral, or lateral membranous reactivity irrespective of percentage of cancer cells positive)</option>
</select></td>
</tr>
<tr>
<td rowspan="2" valign="top"><label class="description">- <a href=".\cap\StomachHER2_CAP_ACCP_ASCO.pdf" target="_blank">HER2 IHC, excision </a> : </label>
(10% cancer cells)
</td>
<td><select class="element select large" ID="A07">
<option value=""></option>
<option value="Cannot be determined">Cannot be determined</option>
<option value="Negative for over-expression">Negative for over-expression</option>
<option value="Equivocal for over-expression">Equivocal for over-expression</option>
<option value="Positive for over-expression">Positive for over-expression</option>
</select></td>
</tr>
<tr>
<td align="right"><label>- Score:</label>
<select class="element select medium" ID="A08">
<option value=""></option>
<option value="0 Negative (No reactivity or membranous reactivity in < 10% of cancer cells)">0 Negative (No reactivity or membranous reactivity in < 10% of cancer cells)</option>
<option value="1 Negative (Faint or barely perceptible membranous react ivity in > or = 10% of cancer cells; cells are reactive only in part of their membrane)">1 Negative (Faint or barely perceptible membranous react ivity in > or = 10% of cancer cells; cells are reactive only in part of their membrane)</option>
<option value="2 Equivocal (Weak to moderate complete, bassolateral or lateral membranous reactivity in > or = 10% of tumor cells)">2 Equivocal (Weak to moderate complete, basolateral or lateral membranous reactivity in > or = 10% of tumor cells)</option>
<option value="3 Positive (Strong complete, basolateral or lateral membranous reactivity in > or = 10% of cancer cells)">3 Positive (Strong complete, basolateral or lateral membranous reactivity in > or = 10% of cancer cells)</option>
</select></td>
</tr>
<tr>
<td rowspan="6" valign="top"><label class="description">- <a href=".\cap\StomachHER2_CAP_ACCP_ASCO.pdf" target="_blank">HER2/neu oncoprotein DISH :</a> </label>
<a href=".\Biomarker-DISH-calculator.html" target="_blank">HER2 DISH calculator</a>
<br>
<a href=".\cap\her2_dish.xlsx" target="_blank">DOWNLOAD AN EXCEL FILE</a>
</td>
<td><select class="element select large" ID="A09">
<option value=""></option>
<option value="Cannot be determined">Cannot be determined</option>
<option value="Negative for HER2 amplification">Negative for HER2 amplification</option>
<option value="Positive for HER2 amplification">Positive for HER2 amplification</option>
</select></td>
</tr>
<tr>
<td align="right">- Number of tumor cell counted :
<input type="text" ID="A10" class="element text small" size="10"></td>
</tr>
<tr>
<td align="right">- HER2 signals (black) per cell :
<input type="text" ID="A11" class="element text small" size="10"></td>
</tr>
<tr>
<td align="right">- CEP17 signals (red) per cell :
<input type="text" ID="A12" class="element text small" size="10"></td>
</tr>
<tr>
<td align="right">- HER2/CEP17 ratio :
<input type="text" ID="A13" class="element text small" size="10"></td>
</tr>
<tr>
<td>- Other ISH abnormalities:<br>
<input type="checkbox" id="A14" value=" - Aneusomy"><label>Aneusomy</label><br>
<input type="checkbox" id="A15" value=" - Heterogeneous signals"><label >Heterogeneous signals</label><br>
<br>
</td>
<br>
</tr>
<tr>
<td>
<label>- Fixation time in buffered formalin :</label>
</td>
<td>
<select class="element select large" ID="A18">
<option value=""></option>
<option value="Optimal fixation (6-72 hours)">Optimal fixation (6-72 hours)</option>
<option value="Prolonged intervals (> 72 hours)">Prolonged intervals (> 72 hours)</option>
<option value="Uncertain">Uncertain</option>
</select>
</td>
</table>
</p>
</fieldset>
</p>
<p>
<label class="description">- Additional notes:</label>
<textarea ID="A19" class = "element textarea medium" style="border-color:grey;"></textarea>
</p>
<br><br>
<input type="button" name="copyform" value="Check your Report" onclick="updateDescription(this.form)"/>
<br>
<TEXTAREA ID="holdtext" name="holdtext" class="textarea large" style="border-color:coral;"></TEXTAREA>
<br><br>
<!-- The button used to copy the text -->
<button onclick="CopyToClipboard()">Copy text to Clipboard</button>
<input type="reset" value="Reset Form" name="reset" style="float: right;">
</form>
<br>
<br>
<div id="footer">
Last upated 06-June-2020, based on <a href="https://www.cap.org/protocols-and-guidelines/cancer-reporting-tools/cancer-protocol-templates" target="_blank">US CAP cancer protocol templates</a>.<br>
html form was created on <a href="https://www.phpform.org">pForm</a>, <a href="https://www.w3schools.com/">W3 School</a>, <a href="https://stackoverflow.com/">StackOverflow</a>, and <a href="https://icons8.com">Icons8</a>.<br><br>
Anatomical Pathology Division, Queen Mary Hospital, Hong Kong.
</div>
</div>
<img id="bottom" src="bottom.png" alt="">
</body>
</html>