diff --git a/.changes/next-release/enhancement-Python-365.json b/.changes/next-release/enhancement-Python-365.json
new file mode 100644
index 0000000000..306b4d8b26
--- /dev/null
+++ b/.changes/next-release/enhancement-Python-365.json
@@ -0,0 +1,5 @@
+{
+  "type": "enhancement",
+  "category": "Python",
+  "description": "Added provisional Python 3.13 support to Botocore"
+}
diff --git a/.github/workflows/run-crt-test.yml b/.github/workflows/run-crt-test.yml
index ff18ec5d28..0a3f6a426f 100644
--- a/.github/workflows/run-crt-test.yml
+++ b/.github/workflows/run-crt-test.yml
@@ -14,7 +14,7 @@ jobs:
     strategy:
       fail-fast: false
       matrix:
-        python-version: ['3.8', '3.9', '3.10', '3.11', '3.12']
+        python-version: ['3.8', '3.9', '3.10', '3.11', '3.12', '3.13']
         os: [ubuntu-latest, macOS-latest, windows-latest]
         # Python 3.8 and 3.9 do not run on m1 hardware which is now standard for
         # macOS-latest.
@@ -32,6 +32,8 @@ jobs:
         uses: actions/setup-python@f677139bbe7f9c59b41e40162b753c062f5d49a3
         with:
           python-version: '${{ matrix.python-version }}'
+          cache: 'pip'
+          allow-prereleases: true
       - name: Install dependencies and CRT
         run: |
           python scripts/ci/install --extras crt
diff --git a/.github/workflows/run-tests.yml b/.github/workflows/run-tests.yml
index af643e1ce1..b21498044c 100644
--- a/.github/workflows/run-tests.yml
+++ b/.github/workflows/run-tests.yml
@@ -14,7 +14,7 @@ jobs:
     strategy:
       fail-fast: false
       matrix:
-        python-version: ['3.8', '3.9', '3.10', '3.11', '3.12']
+        python-version: ['3.8', '3.9', '3.10', '3.11', '3.12', '3.13']
         os: [ubuntu-latest, macOS-latest, windows-latest]
         # Python 3.8 and 3.9 do not run on m1 hardware which is now standard for
         # macOS-latest.
@@ -32,6 +32,8 @@ jobs:
         uses: actions/setup-python@f677139bbe7f9c59b41e40162b753c062f5d49a3
         with:
           python-version: '${{ matrix.python-version }}'
+          cache: 'pip'
+          allow-prereleases: true
       - name: Install dependencies
         run: |
           python scripts/ci/install
diff --git a/setup.py b/setup.py
index 26ddfb4a18..d0e487020d 100644
--- a/setup.py
+++ b/setup.py
@@ -68,5 +68,6 @@ def find_version(*file_paths):
         'Programming Language :: Python :: 3.10',
         'Programming Language :: Python :: 3.11',
         'Programming Language :: Python :: 3.12',
+        'Programming Language :: Python :: 3.13',
     ],
 )
diff --git a/tox.ini b/tox.ini
index 9014a42fe6..38a9c3197d 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,5 +1,5 @@
 [tox]
-envlist = py38,py39,py310,py311,py312
+envlist = py38,py39,py310,py311,py312,py313
 
 skipsdist = True