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InProgress Overview

This pacakge is designed to take MANTA or SvABA VCF files which have been run without a paired normal and classify each rearrangement as germline or somatic.

System Requirements and Dependencies

  • This has been tested on the current versions of OSX, Linux, Ubuntu, Windows (as of April 1, 2022)

Installation

  1. Install R-4.0 or newer (https://www.r-project.org/)
  2. Install necessary packages
install.pacakges('devtools')
install.packages('parallel')
install.packages('BiocManager')

library(BiocManager)
BiocManager::install('GenomicRanges')

library(devtools)
devtools::install_github('mskilab/gUtils')

Documentation for these packages can be found at:
devtools
parallel
BiocManager
GenomicRanges
gUtils

  1. Install InProgress
Sys.setenv(R_REMOTES_NO_ERRORS_FROM_WARNINGS=TRUE) 
devtools::install_github('acranej/InProgress')