diff --git a/src/plugins/es_ui_shared/public/request/request.test.js b/src/plugins/es_ui_shared/public/request/request.test.js
index 60b05a8dc8a27..c34a4bfbe2e32 100644
--- a/src/plugins/es_ui_shared/public/request/request.test.js
+++ b/src/plugins/es_ui_shared/public/request/request.test.js
@@ -41,7 +41,12 @@ const testHook = (callback) => {
 const wait = async wait =>
   new Promise(resolve => setTimeout(resolve, wait || 1));
 
-describe('request lib', () => {
+// FLAKY:
+// - https://github.com/elastic/kibana/issues/42561
+// - https://github.com/elastic/kibana/issues/42562
+// - https://github.com/elastic/kibana/issues/42563
+// - https://github.com/elastic/kibana/issues/42225
+describe.skip('request lib', () => {
   const successRequest = { path: '/success', method: 'post', body: {} };
   const errorRequest = { path: '/error', method: 'post', body: {} };
   const successResponse = { statusCode: 200, data: { message: 'Success message' } };