diff --git a/packages/components/CHANGELOG.md b/packages/components/CHANGELOG.md
index d9e21c2788d9e2..914e9e771ddff1 100644
--- a/packages/components/CHANGELOG.md
+++ b/packages/components/CHANGELOG.md
@@ -6,6 +6,10 @@
 
 -   `ComboboxControl`: Introduce Combobox expandOnFocus prop ([#61705](https://github.com/WordPress/gutenberg/pull/61705)).
 
+### Bug Fixes
+
+-   `Autocomplete`: Stabilize rendering of autocomplete items ([#61877](https://github.com/WordPress/gutenberg/pull/61877)).
+
 ### Internal
 
 -   Add type support for CSS Custom Properties ([#61872](https://github.com/WordPress/gutenberg/pull/61872)).
diff --git a/packages/components/src/autocomplete/autocompleter-ui.tsx b/packages/components/src/autocomplete/autocompleter-ui.tsx
index a3e3cb503c483e..a22e197decd154 100644
--- a/packages/components/src/autocomplete/autocompleter-ui.tsx
+++ b/packages/components/src/autocomplete/autocompleter-ui.tsx
@@ -27,10 +27,57 @@ import { VisuallyHidden } from '../visually-hidden';
 import { createPortal } from 'react-dom';
 import type { AutocompleterUIProps, KeyedOption, WPCompleter } from './types';
 
+type ListBoxProps = {
+	items: KeyedOption[];
+	onSelect: ( option: KeyedOption ) => void;
+	selectedIndex: number;
+	instanceId: number;
+	listBoxId: string | undefined;
+	className?: string;
+	Component?: React.ElementType;
+};
+
+function ListBox( {
+	items,
+	onSelect,
+	selectedIndex,
+	instanceId,
+	listBoxId,
+	className,
+	Component = 'div',
+}: ListBoxProps ) {
+	return (
+		<Component
+			id={ listBoxId }
+			role="listbox"
+			className="components-autocomplete__results"
+		>
+			{ items.map( ( option, index ) => (
+				<Button
+					key={ option.key }
+					id={ `components-autocomplete-item-${ instanceId }-${ option.key }` }
+					role="option"
+					aria-selected={ index === selectedIndex }
+					disabled={ option.isDisabled }
+					className={ clsx(
+						'components-autocomplete__result',
+						className,
+						{
+							'is-selected': index === selectedIndex,
+						}
+					) }
+					onClick={ () => onSelect( option ) }
+				>
+					{ option.label }
+				</Button>
+			) ) }
+		</Component>
+	);
+}
+
 export function getAutoCompleterUI( autocompleter: WPCompleter ) {
-	const useItems = autocompleter.useItems
-		? autocompleter.useItems
-		: getDefaultUseItems( autocompleter );
+	const useItems =
+		autocompleter.useItems ?? getDefaultUseItems( autocompleter );
 
 	function AutocompleterUI( {
 		filterValue,
@@ -62,7 +109,7 @@ export function getAutoCompleterUI( autocompleter: WPCompleter ) {
 					// If the popover is rendered in a different document than
 					// the content, we need to duplicate the options list in the
 					// content document so that it's available to the screen
-					// readers, which check the DOM ID based aira-* attributes.
+					// readers, which check the DOM ID based aria-* attributes.
 					setNeedsA11yCompat(
 						node.ownerDocument !== contentRef.current.ownerDocument
 					);
@@ -124,38 +171,6 @@ export function getAutoCompleterUI( autocompleter: WPCompleter ) {
 			return null;
 		}
 
-		const ListBox = ( {
-			Component = 'div',
-		}: {
-			Component?: React.ElementType;
-		} ) => (
-			<Component
-				id={ listBoxId }
-				role="listbox"
-				className="components-autocomplete__results"
-			>
-				{ items.map( ( option, index ) => (
-					<Button
-						key={ option.key }
-						id={ `components-autocomplete-item-${ instanceId }-${ option.key }` }
-						role="option"
-						aria-selected={ index === selectedIndex }
-						disabled={ option.isDisabled }
-						className={ clsx(
-							'components-autocomplete__result',
-							className,
-							{
-								'is-selected': index === selectedIndex,
-							}
-						) }
-						onClick={ () => onSelect( option ) }
-					>
-						{ option.label }
-					</Button>
-				) ) }
-			</Component>
-		);
-
 		return (
 			<>
 				<Popover
@@ -166,12 +181,27 @@ export function getAutoCompleterUI( autocompleter: WPCompleter ) {
 					anchor={ popoverAnchor }
 					ref={ popoverRefs }
 				>
-					<ListBox />
+					<ListBox
+						items={ items }
+						onSelect={ onSelect }
+						selectedIndex={ selectedIndex }
+						instanceId={ instanceId }
+						listBoxId={ listBoxId }
+						className={ className }
+					/>
 				</Popover>
 				{ contentRef.current &&
 					needsA11yCompat &&
 					createPortal(
-						<ListBox Component={ VisuallyHidden } />,
+						<ListBox
+							items={ items }
+							onSelect={ onSelect }
+							selectedIndex={ selectedIndex }
+							instanceId={ instanceId }
+							listBoxId={ listBoxId }
+							className={ className }
+							Component={ VisuallyHidden }
+						/>,
 						contentRef.current.ownerDocument.body
 					) }
 			</>
diff --git a/test/e2e/specs/editor/various/autocomplete-and-mentions.spec.js b/test/e2e/specs/editor/various/autocomplete-and-mentions.spec.js
index aae72f50cd25f1..059f3a73ee13d8 100644
--- a/test/e2e/specs/editor/various/autocomplete-and-mentions.spec.js
+++ b/test/e2e/specs/editor/various/autocomplete-and-mentions.spec.js
@@ -421,6 +421,43 @@ test.describe( 'Autocomplete (@firefox, @webkit)', () => {
 		} );
 	} );
 
+	test( `should insert mention in a table block`, async ( {
+		page,
+		editor,
+	} ) => {
+		// Insert table block.
+		await editor.insertBlock( { name: 'core/table' } );
+
+		// Create the table.
+		await editor.canvas
+			.locator( 'role=button[name="Create Table"i]' )
+			.click();
+
+		// Select the first cell.
+		await editor.canvas
+			.locator( 'role=textbox[name="Body cell text"i] >> nth=0' )
+			.click();
+
+		// Type autocomplete text.
+		await page.keyboard.type( '@j' );
+
+		// Verify that option is selected.
+		const selectedOption = page.getByRole( 'option', {
+			name: 'Jane Doe',
+			selected: true,
+		} );
+		await expect( selectedOption ).toBeVisible();
+
+		// Insert the option.
+		await selectedOption.click();
+
+		// Verify it's been inserted.
+		const snapshot = `<!-- wp:table -->
+<figure class="wp-block-table"><table class="has-fixed-layout"><tbody><tr><td>@testuser</td><td></td></tr><tr><td></td><td></td></tr></tbody></table></figure>
+<!-- /wp:table -->`;
+		await expect.poll( editor.getEditedPostContent ).toBe( snapshot );
+	} );
+
 	// The following test concerns an infinite loop regression (https://github.com/WordPress/gutenberg/issues/41709).
 	// When present, the regression will cause this test to time out.
 	test( 'should insert elements from multiple completers in a single block', async ( {