diff --git a/packages/components/CHANGELOG.md b/packages/components/CHANGELOG.md
index 1ff727b29145db..a6b1fff372a940 100644
--- a/packages/components/CHANGELOG.md
+++ b/packages/components/CHANGELOG.md
@@ -49,6 +49,7 @@
 -   `Sandbox`: updated to satisfy `react/exhaustive-deps` eslint rule ([#44378](https://github.com/WordPress/gutenberg/pull/44378))
 -   `FontSizePicker`: Convert to TypeScript ([#44449](https://github.com/WordPress/gutenberg/pull/44449)).
 -   `FontSizePicker`: Replace SCSS with Emotion + components ([#44483](https://github.com/WordPress/gutenberg/pull/44483)).
+-   `Tooltip`: updated to ignore `react/exhaustive-deps` eslint rule ([#45043](https://github.com/WordPress/gutenberg/pull/45043))
 
 ### Experimental
 
diff --git a/packages/components/src/tooltip/index.js b/packages/components/src/tooltip/index.js
index c4b8a5ea6c147c..491c7a76a97cda 100644
--- a/packages/components/src/tooltip/index.js
+++ b/packages/components/src/tooltip/index.js
@@ -228,6 +228,9 @@ function Tooltip( props ) {
 		document.removeEventListener( 'mouseup', cancelIsMouseDown );
 	};
 
+	// Ignore reason: updating the deps array here could cause unexpected changes in behavior.
+	// Deferring until a more detailed investigation/refactor can be performed.
+	// eslint-disable-next-line react-hooks/exhaustive-deps
 	useEffect( () => clearOnUnmount, [] );
 
 	if ( Children.count( children ) !== 1 ) {
diff --git a/packages/components/src/tooltip/index.native.js b/packages/components/src/tooltip/index.native.js
index 4fd8de0814e66f..61b08c052dfacc 100644
--- a/packages/components/src/tooltip/index.native.js
+++ b/packages/components/src/tooltip/index.native.js
@@ -62,6 +62,9 @@ const useKeyboardVisibility = () => {
 			showListener.remove();
 			hideListener.remove();
 		};
+		// Disable reason: deferring this refactor to the native team.
+		// see https://github.com/WordPress/gutenberg/pull/41166
+		// eslint-disable-next-line react-hooks/exhaustive-deps
 	}, [] );
 
 	return keyboardVisible;
@@ -102,6 +105,9 @@ const Tooltip = ( {
 			} );
 		}
 		return () => onHandleScreenTouch( null );
+		// Disable reason: deferring this refactor to the native team.
+		// see https://github.com/WordPress/gutenberg/pull/41166
+		// eslint-disable-next-line react-hooks/exhaustive-deps
 	}, [ visible ] );
 
 	// Manage visibility animation.
@@ -115,6 +121,9 @@ const Tooltip = ( {
 			setAnimating( true );
 			startAnimation();
 		}
+		// Disable reason: deferring this refactor to the native team.
+		// see https://github.com/WordPress/gutenberg/pull/41166
+		// eslint-disable-next-line react-hooks/exhaustive-deps
 	}, [ visible ] );
 
 	// Manage tooltip visibility and position in relation to keyboard.
@@ -133,6 +142,9 @@ const Tooltip = ( {
 			setAnimating( true );
 			setVisible( false );
 		}
+		// Disable reason: deferring this refactor to the native team.
+		// see https://github.com/WordPress/gutenberg/pull/41166
+		// eslint-disable-next-line react-hooks/exhaustive-deps
 	}, [ visible, keyboardVisible ] );
 
 	// Manage tooltip position during keyboard frame changes.
@@ -261,6 +273,9 @@ const TooltipSlot = ( { children, ...rest } ) => {
 		setHandleScreenTouch( null );
 	};
 	// Memoize context value to avoid unnecessary rerenders of the Provider's children
+	// Disable reason: deferring this refactor to the native team.
+	// see https://github.com/WordPress/gutenberg/pull/41166
+	// eslint-disable-next-line react-hooks/exhaustive-deps
 	const value = useMemo( () => ( { onHandleScreenTouch } ) );
 
 	return (