diff --git a/packages/env/README.md b/packages/env/README.md
index c10bbdcf62dcbd..97afe66a561a93 100644
--- a/packages/env/README.md
+++ b/packages/env/README.md
@@ -392,6 +392,7 @@ You can customize the WordPress installation, plugins and themes that the develo
 | `"port"`       | `integer`      | `8888` (`8889` for the tests instance) | The primary port number to use for the installation. You'll access the instance through the port: 'http://localhost:8888'.       |
 | `"config"`     | `Object`       | See below.                             | Mapping of wp-config.php constants to their desired values.                                                                      |
 | `"mappings"`   | `Object`       | `"{}"`                                 | Mapping of WordPress directories to local directories to be mounted in the WordPress instance.                                   |
+| `"phpConfig"`  | `Object`       | `"{}"`                                 | PHP configuration directives.
 
 _Note: the port number environment variables (`WP_ENV_PORT` and `WP_ENV_TESTS_PORT`) take precedent over the .wp-env.json values._
 
@@ -548,6 +549,29 @@ If you need a plugin active in one environment but not the other, you can use `e
 }
 ```
 
+#### Custom PHP Configuration.
+
+You can customize the configuration of PHP via `phpConfig`.
+
+```json
+{
+	"phpConfig": {
+		"memory_limit": "512M",
+		"post_max_size": "512M",
+		"upload_max_filesize": "512M"
+	}
+}
+```
+
+The settings will be added to `.htaccess`.
+
+```apacheconf
+php_value memory_limit 512M
+php_value post_max_size 512M
+php_value upload_max_filesize 512M
+```
+
+
 #### Custom Port Numbers
 
 You can tell `wp-env` to use a custom port number so that your instance does not conflict with other `wp-env` instances.
diff --git a/packages/env/lib/config/config.js b/packages/env/lib/config/config.js
index 401077c495f30d..42a7bc4ef44091 100644
--- a/packages/env/lib/config/config.js
+++ b/packages/env/lib/config/config.js
@@ -86,6 +86,7 @@ module.exports = async function readConfig( configPath ) {
 			WP_SITEURL: 'http://localhost',
 			WP_HOME: 'http://localhost',
 		},
+		phpConfig: {},
 		env: {
 			development: {}, // No overrides needed, but it should exist.
 			tests: {
diff --git a/packages/env/lib/config/parse-config.js b/packages/env/lib/config/parse-config.js
index a0877fcb059451..17bbc2d296b270 100644
--- a/packages/env/lib/config/parse-config.js
+++ b/packages/env/lib/config/parse-config.js
@@ -47,6 +47,7 @@ module.exports = function parseConfig( config, options ) {
 			parseSourceString( sourceString, options )
 		),
 		config: config.config,
+		phpConfig: config.phpConfig,
 		mappings: Object.entries( config.mappings ).reduce(
 			( result, [ wpDir, localDir ] ) => {
 				const source = parseSourceString( localDir, options );
diff --git a/packages/env/lib/config/test/__snapshots__/config.js.snap b/packages/env/lib/config/test/__snapshots__/config.js.snap
index 230796119d6e19..51a2fb04102a72 100644
--- a/packages/env/lib/config/test/__snapshots__/config.js.snap
+++ b/packages/env/lib/config/test/__snapshots__/config.js.snap
@@ -23,6 +23,7 @@ Object {
       },
       "coreSource": null,
       "mappings": Object {},
+      "phpConfig": Object {},
       "phpVersion": null,
       "pluginSources": Array [],
       "port": 2000,
@@ -46,6 +47,7 @@ Object {
       },
       "coreSource": null,
       "mappings": Object {},
+      "phpConfig": Object {},
       "phpVersion": null,
       "pluginSources": Array [],
       "port": 1000,
diff --git a/packages/env/lib/config/validate-config.js b/packages/env/lib/config/validate-config.js
index c3aa849e6322d1..4ddf8e9a4f865b 100644
--- a/packages/env/lib/config/validate-config.js
+++ b/packages/env/lib/config/validate-config.js
@@ -83,6 +83,12 @@ function validateConfig( config, envLocation ) {
 		);
 	}
 
+	if ( typeof config.phpConfig !== 'object' ) {
+		throw new ValidationError(
+			'Invalid .wp-env.json: "phpConfig" must be an object.'
+		);
+	}
+
 	return config;
 }
 
diff --git a/packages/env/lib/wordpress.js b/packages/env/lib/wordpress.js
index 0cbd70c4ab22b9..c00bc13e199622 100644
--- a/packages/env/lib/wordpress.js
+++ b/packages/env/lib/wordpress.js
@@ -64,6 +64,17 @@ async function configureWordPress( environment, config, spinner ) {
 	for ( const pluginSource of config.env[ environment ].pluginSources ) {
 		setupCommands.push( `wp plugin activate ${ pluginSource.basename }` );
 	}
+	const phpConfig = Object.entries( config.env[ environment ].phpConfig )
+		.map( ( [ key, value ] ) => {
+			const phpConfigValue =
+				typeof value === 'string' ? `"${ value }"` : value;
+			return `php_value ${ key } ${ phpConfigValue }`;
+		} )
+		.join( '\n' );
+
+	setupCommands.push(
+		`wp eval "insert_with_markers( get_home_path().'.htaccess', 'wp-env', '${ phpConfig }' );"`
+	);
 
 	if ( config.debug ) {
 		spinner.info(