diff --git a/packages/components/src/autocomplete/index.js b/packages/components/src/autocomplete/index.js
index 3c66e5f4d21cfd..38a5a0d58fd6bb 100644
--- a/packages/components/src/autocomplete/index.js
+++ b/packages/components/src/autocomplete/index.js
@@ -409,7 +409,7 @@ export class Autocomplete extends Component {
 				break;
 
 			case ESCAPE:
-				this.setState( { autocompleter: null } );
+				this.setState( { autocompleter: null, AutocompleterUI: null } );
 				break;
 
 			case ENTER:
@@ -428,6 +428,7 @@ export class Autocomplete extends Component {
 		// Any handled keycode should prevent original behavior. This relies on
 		// the early return in the default case.
 		event.preventDefault();
+		event.stopPropagation();
 	}
 
 	componentDidUpdate( prevProps ) {