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How to match my TCR sequence reported by TraCer with my 10X Cellranger vdj output Clonalcall? #120

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MugenQin opened this issue Sep 8, 2022 · 0 comments
Open

How to match my TCR sequence reported by TraCer with my 10X Cellranger vdj output Clonalcall? #120

MugenQin opened this issue Sep 8, 2022 · 0 comments

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@MugenQin
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MugenQin commented Sep 8, 2022

Hi,
Thanks for your effort for developing TraCer! It's very convenient for us to get the clonotypes.
Now I want to project my single cell full-length TCR to my 10X scRNA+TCR seq data. So I need to match them through the same TCR sequence. After reading your paper, I know that TraCer reported V genes & junction sequences & J genes. But 10X cellranger VDJ can report VDJ gens or CDR3 sequences.
I got the puzzle about how to use the output sequences of both softwares and match them. Could you give me some advice?
Thanks
Qin
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@MugenQin