diff --git a/R/Dockerfile b/R/Dockerfile
index bbc1d71..afd6371 100644
--- a/R/Dockerfile
+++ b/R/Dockerfile
@@ -51,6 +51,7 @@ RUN R -f /tmp/install.R
 
 # install the python dependencies
 COPY requirements.txt /tmp/
-RUN pip3 install -r /tmp/requirements.txt --no-cache-dir
+RUN pip3 install -r /tmp/requirements.txt --no-cache-dir && \
+    rm -rf ${HOME}/.renku/venv
 
 COPY --from=builder ${HOME}/.renku/venv ${HOME}/.renku/venv
diff --git a/bioc/Dockerfile b/bioc/Dockerfile
index 0365506..3ae1daa 100644
--- a/bioc/Dockerfile
+++ b/bioc/Dockerfile
@@ -51,6 +51,7 @@ RUN R -f /tmp/install.R
 
 # install the python dependencies
 COPY requirements.txt /tmp/
-RUN pip3 install -r /tmp/requirements.txt --no-cache-dir
+RUN pip3 install -r /tmp/requirements.txt --no-cache-dir && \
+    rm -rf ${HOME}/.renku/venv
 
 COPY --from=builder ${HOME}/.renku/venv ${HOME}/.renku/venv
diff --git a/julia/Dockerfile b/julia/Dockerfile
index b5f2394..43da9b2 100644
--- a/julia/Dockerfile
+++ b/julia/Dockerfile
@@ -56,6 +56,7 @@ RUN mamba env update -q -f /tmp/environment.yml && \
 COPY Project.toml Manifest.toml /tmp/
 RUN mkdir /tmp/julia-pkg && \
     cp /tmp/Project.toml /tmp/Manifest.toml /tmp/julia-pkg/ && \
-    julia -e'using Pkg; Pkg.activate("/tmp/julia-pkg/"); Pkg.instantiate(); Pkg.precompile()'
+    julia -e'using Pkg; Pkg.activate("/tmp/julia-pkg/"); Pkg.instantiate(); Pkg.precompile()' && \
+    rm -rf ${HOME}/.renku/venv
 
 COPY --from=builder ${HOME}/.renku/venv ${HOME}/.renku/venv
diff --git a/minimal/Dockerfile b/minimal/Dockerfile
index cddd470..922e888 100644
--- a/minimal/Dockerfile
+++ b/minimal/Dockerfile
@@ -57,4 +57,6 @@ FROM ${RENKU_BASE_IMAGE}
 #    conda clean -y --all && \
 #    conda env export -n "root"
 
+RUN rm -rf ${HOME}/.renku/venv
+
 COPY --from=builder ${HOME}/.renku/venv ${HOME}/.renku/venv
diff --git a/python/Dockerfile b/python/Dockerfile
index 2320150..2386f5b 100644
--- a/python/Dockerfile
+++ b/python/Dockerfile
@@ -50,6 +50,7 @@ COPY requirements.txt environment.yml /tmp/
 RUN mamba env update -q -f /tmp/environment.yml && \
     /opt/conda/bin/pip install -r /tmp/requirements.txt --no-cache-dir && \
     mamba clean -y --all && \
-    mamba env export -n "root"
+    mamba env export -n "root" && \
+    rm -rf ${HOME}/.renku/venv
 
 COPY --from=builder ${HOME}/.renku/venv ${HOME}/.renku/venv