diff --git a/qubes/tests/integ/vm_qrexec_gui.py b/qubes/tests/integ/vm_qrexec_gui.py
index e55671963..19e9c3392 100644
--- a/qubes/tests/integ/vm_qrexec_gui.py
+++ b/qubes/tests/integ/vm_qrexec_gui.py
@@ -98,7 +98,8 @@ def prepare_audio_test(self, backend):
         if backend == 'pipewire':
             if not self.testvm1.features.check_with_template('supported-service.pipewire', False):
                 self.skipTest('PipeWire not supported in VM')
-            if 'debian-11' in self.template or 'whonix' in self.template:
+            if 'debian-11' in self.template or (
+                    'whonix' in self.template and '16' in self.template):
                 self.skipTest('PipeWire audio not supported in Debian 11')
             self.testvm1.features['service.pipewire'] = True
         elif backend == 'pulseaudio':