Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Include an option in GenScorePipeline to include every found variant #8

Open
kbeutel opened this issue Oct 31, 2023 · 1 comment
Open

Comments

@kbeutel
Copy link
Contributor

kbeutel commented Oct 31, 2023

From Abby:
Currently, if there are variants listed in a .meta file that have the same position, and both variants exist in the dataset, only one will be returned and included in the score, even when minWinSize=0. It would be nice to have an option (perhaps a minWinSize=-1 or something similar) where every variant in .meta that exists in the dataset would be included (I.e. no variants would be left out simply because of the same or a nearby position). This would be helpful for instances where a score generated from variants all within a gene/similar location and overlap/close proximity of variants is likely.

@kbeutel
Copy link
Contributor Author

kbeutel commented Oct 31, 2023

From Nathan:
To test, make some .meta files with:

the same name for different chr/position/ref/alt (preferably with the same position, just different alts) -> should throw an exception that you need to manually change the names to be unique, but will be supported when that happens

the same name for the same chr/position/ref/alt (accidental duplicated line; we can't support this)

different names for the same chr/position/ref/alt (problem we can't support)

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Projects
None yet
Development

No branches or pull requests

1 participant