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TRGT v1.1.0
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@tmokveld tmokveld released this 17 Jul 13:09
· 5 commits to main since this release
v1.1.0
4b7576d

Summary of changes:

  • Added a new subcommand trgt merge. This command merges VCF files generated by trgt genotype into a joint VCF file. Works with VCFs generated by all versions of TRGT (the resulting joint VCF will always be in the TRGT v1.0+ format which includes padding bases).
  • Added subsampling of regions with ultra-high coverage (>MAX_DEPTH * 3, by default 750); implemented via reservoir sampling.
  • Fixed a cluster genotyper bug that occurred when only a single read covered a locus.
  • Added new logic for filtering non-HiFi reads: remove up to 3% of lower quality reads that do not match the expected repeat sequence.

Contributors: Tom Mokveld, Guilherme De Sena Brandine, and Egor Dolzhenko

Note: TRGT is still in active development. Please file an issue or reach out by email with questions, bug reports, and feature suggestions.

Linux binaries are available below.

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