diff --git a/cache/async_cache.go b/cache/async_cache.go
index 6ecd3d67..1b9ccdd2 100644
--- a/cache/async_cache.go
+++ b/cache/async_cache.go
@@ -20,6 +20,8 @@ type AsyncCache struct {
 	TransactionRegistry
 
 	graceTime time.Duration
+
+	MaxPayloadSize int64
 }
 
 func (c *AsyncCache) Close() error {
@@ -103,9 +105,12 @@ func NewAsyncCache(cfg config.Cache, maxExecutionTime time.Duration) (*AsyncCach
 		return nil, err
 	}
 
+	maxPayloadSize := int64(cfg.MaxPayloadSize)
+
 	return &AsyncCache{
 		Cache:               cache,
 		TransactionRegistry: transaction,
 		graceTime:           graceTime,
+		MaxPayloadSize:      maxPayloadSize,
 	}, nil
 }
diff --git a/cache/async_cache_test.go b/cache/async_cache_test.go
index ed059cb1..e6a07b1e 100644
--- a/cache/async_cache_test.go
+++ b/cache/async_cache_test.go
@@ -214,6 +214,7 @@ func TestAsyncCache_FilesystemCache_instantiation(t *testing.T) {
 			MaxSize: 8192,
 		},
 		Expire: config.Duration(time.Minute),
+		MaxPayloadSize: config.ByteSize(100000000),
 	}
 	if err := os.RemoveAll(testDirAsync); err != nil {
 		log.Fatalf("cannot remove %q: %s", testDirAsync, err)
@@ -249,6 +250,7 @@ func TestAsyncCache_RedisCache_instantiation(t *testing.T) {
 			Addresses: []string{s.Addr()},
 		},
 		Expire: config.Duration(cacheTTL),
+		MaxPayloadSize: config.ByteSize(100000000),
 	}
 
 	_, err := NewAsyncCache(redisCfg, 1*time.Second)
diff --git a/config/config.go b/config/config.go
index 85656940..ecc84649 100644
--- a/config/config.go
+++ b/config/config.go
@@ -32,6 +32,8 @@ var (
 	}
 
 	defaultExecutionTime = Duration(30 * time.Second)
+
+	defaultMaxPayloadSize = ByteSize(100000000)
 )
 
 // Config describes server configuration, access and proxy rules
@@ -609,6 +611,9 @@ type Cache struct {
 
 	// Catches all undefined fields
 	XXX map[string]interface{} `yaml:",inline"`
+
+	// Maximum total size of request payload for caching
+	MaxPayloadSize ByteSize `yaml:"max_payload_size,omitempty"`
 }
 
 type FileSystemCacheConfig struct {
@@ -820,6 +825,13 @@ func LoadFile(filename string) (*Config, error) {
 		}
 	}
 
+	for i := range cfg.Caches {
+		c := &cfg.Caches[i]
+		if c.MaxPayloadSize <= 0 {
+			c.MaxPayloadSize = defaultMaxPayloadSize
+		}
+	}
+
 	if maxResponseTime < 0 {
 		maxResponseTime = 0
 	}
diff --git a/config/config_test.go b/config/config_test.go
index fa976e50..9a2f6706 100644
--- a/config/config_test.go
+++ b/config/config_test.go
@@ -21,8 +21,9 @@ var fullConfig = Config{
 				Dir:     "/path/to/longterm/cachedir",
 				MaxSize: ByteSize(100 << 30),
 			},
-			Expire:    Duration(time.Hour),
-			GraceTime: Duration(20 * time.Second),
+			Expire:         Duration(time.Hour),
+			GraceTime:      Duration(20 * time.Second),
+			MaxPayloadSize: ByteSize(100 << 30),
 		},
 		{
 			Name: "shortterm",
@@ -31,7 +32,8 @@ var fullConfig = Config{
 				Dir:     "/path/to/shortterm/cachedir",
 				MaxSize: ByteSize(100 << 20),
 			},
-			Expire: Duration(10 * time.Second),
+			Expire:         Duration(10 * time.Second),
+			MaxPayloadSize: ByteSize(100 << 20),
 		},
 	},
 	HackMePlease: true,
@@ -452,6 +454,11 @@ func TestBadConfig(t *testing.T) {
 			"testdata/bad.heartbeat_section.empty2.yml",
 			"cannot be use `heartbeat_interval` with `heartbeat` section",
 		},
+		{
+			"max payload size to cache",
+			"testdata/bad.max_payload_size.yml",
+			"cannot parse byte size \"-10B\": it must be positive float followed by optional units. For example, 1Gb, 100Mb",
+		},
 	}
 
 	for _, tc := range testCases {
@@ -827,12 +834,14 @@ caches:
   file_system:
     dir: /path/to/longterm/cachedir
     max_size: 107374182400
+  max_payload_size: 107374182400
 - mode: file_system
   name: shortterm
   expire: 10s
   file_system:
     dir: /path/to/shortterm/cachedir
     max_size: 104857600
+  max_payload_size: 104857600
 param_groups:
 - name: cron-job
   params:
diff --git a/config/testdata/bad.max_payload_size.yml b/config/testdata/bad.max_payload_size.yml
new file mode 100644
index 00000000..3607e06c
--- /dev/null
+++ b/config/testdata/bad.max_payload_size.yml
@@ -0,0 +1,21 @@
+caches:
+  - name: "longterm"
+    mode: "file_system"
+    max_payload_size: "-10B"
+    file_system:
+      dir: "cache_dir"
+      max_size: 100Gb
+
+server:
+  http:
+    listen_addr: ":8080"
+
+users:
+  - name: "dummy"
+    allowed_networks: ["1.2.3.4"]
+    to_cluster: "cluster"
+    to_user: "default"
+
+clusters:
+  - name: "cluster"
+    nodes: ["127.0.1.1:8123"]
diff --git a/config/testdata/full.yml b/config/testdata/full.yml
index 450d66ad..bdfb4e35 100644
--- a/config/testdata/full.yml
+++ b/config/testdata/full.yml
@@ -26,6 +26,8 @@ caches:
       # Path to directory where cached responses will be stored.
       dir: "/path/to/longterm/cachedir"
 
+    max_payload_size: 100Gb
+
     # Expiration time for cached responses.
     expire: 1h
 
@@ -44,6 +46,7 @@ caches:
     file_system:
       max_size: 100Mb
       dir: "/path/to/shortterm/cachedir"
+    max_payload_size: 100Mb
     expire: 10s
 
 # Optional network lists, might be used as values for `allowed_networks`.
diff --git a/proxy.go b/proxy.go
index 2d89fad4..d4cdd212 100644
--- a/proxy.go
+++ b/proxy.go
@@ -339,25 +339,32 @@ func (rp *reverseProxy) serveFromCache(s *scope, srw *statResponseWriter, req *h
 		contentLength := bufferedRespWriter.GetCapturedContentLength()
 		reader := bufferedRespWriter.Reader()
 
-		// we create this buffer to be able to stream data both to cache as well as to an end user
-		var buf bytes.Buffer
-		tee := io.TeeReader(reader, &buf)
-		contentMetadata := cache.ContentMetadata{Length: contentLength, Encoding: contentEncoding, Type: contentType}
-		expiration, err := userCache.Put(tee, contentMetadata, key)
-		if err != nil {
-			log.Errorf("%s: %s; query: %q - failed to put response in the cache", s, err, q)
-		}
+		if isToCache(contentLength, s) {
+			// we create this buffer to be able to stream data both to cache as well as to an end user
+			var buf bytes.Buffer
+			tee := io.TeeReader(reader, &buf)
+			contentMetadata := cache.ContentMetadata{Length: contentLength, Encoding: contentEncoding, Type: contentType}
+			expiration, err := userCache.Put(tee, contentMetadata, key)
+			if err != nil {
+				log.Errorf("%s: %s; query: %q - failed to put response in the cache", s, err, q)
+			}
 
-		// mark transaction as completed
-		if err = userCache.Complete(key); err != nil {
-			log.Errorf("%s: %s; query: %q", s, err, q)
-		}
+			// mark transaction as completed
+			if err = userCache.Complete(key); err != nil {
+				log.Errorf("%s: %s; query: %q", s, err, q)
+			}
 
-		err = RespondWithData(srw, &buf, contentMetadata, expiration, bufferedRespWriter.StatusCode())
-		if err != nil {
-			err = fmt.Errorf("%s: %w; query: %q", s, err, q)
-			respondWith(srw, err, http.StatusInternalServerError)
-			return
+			err = RespondWithData(srw, &buf, contentMetadata, expiration, bufferedRespWriter.StatusCode())
+			if err != nil {
+				err = fmt.Errorf("%s: %w; query: %q", s, err, q)
+				respondWith(srw, err, http.StatusInternalServerError)
+				return
+			}
+		} else {
+			err = RespondWithoutData(srw)
+			if err != nil {
+				log.Errorf("%s: %s; query: %q - failed to put response in the cache", s, err, q)
+			}
 		}
 	}
 }
diff --git a/utils.go b/utils.go
index 6083c223..67978b19 100644
--- a/utils.go
+++ b/utils.go
@@ -288,3 +288,8 @@ func calcMapHash(m map[string]string) (uint32, error) {
 	}
 	return h.Sum32(), nil
 }
+
+func isToCache(length int64, s *scope) bool {
+	maxPayloadSize := s.user.cache.MaxPayloadSize
+	return length <= maxPayloadSize
+}
diff --git a/utils_test.go b/utils_test.go
index 39024b8c..9fbbc31d 100644
--- a/utils_test.go
+++ b/utils_test.go
@@ -354,13 +354,13 @@ func TestCalcMapHash(t *testing.T) {
 		},
 		{
 			"map with multiple value",
-			map[string]string{"param_table_name": "clients","param_database":"default"},
+			map[string]string{"param_table_name": "clients", "param_database": "default"},
 			0x6fddf04d,
 			nil,
 		},
 		{
 			"map with exchange value",
-			map[string]string{"param_database":"default","param_table_name":"clients"},
+			map[string]string{"param_database": "default", "param_table_name": "clients"},
 			0x6fddf04d,
 			nil,
 		},