diff --git a/setup.py b/setup.py
index fec1e3b9f..7551376b9 100644
--- a/setup.py
+++ b/setup.py
@@ -106,7 +106,7 @@ def run(self):
     "fsspec>=2022.8.0,<2023.9.0",
     "imagecodecs>=2020.5.30",
     "lxml>=4.6,<5",
-    "numpy>=1.21.0",
+    "numpy>=1.21.0,<2",
     "ome-types>=0.3.4",
     "ome-zarr>=0.6.1",
     "PyYAML>=6.0",