diff --git a/documentation/conf.py b/documentation/conf.py
index 8fbbd100af..9ceb0317c1 100644
--- a/documentation/conf.py
+++ b/documentation/conf.py
@@ -126,26 +126,7 @@ def install_doxygen():
 
 # Install AMICI if not already present
 typing.TYPE_CHECKING = True
-
-try:
-    import amici
-except ModuleNotFoundError:
-    subprocess.run([
-        'python', '-m', 'pip', 'install', '--verbose', '-e',
-        os.path.join(amici_dir, 'python', 'sdist')
-    ], check=True)
-
-    from importlib import invalidate_caches
-
-    invalidate_caches()
-
-    sys.path.insert(0, amici_dir)
-    sys.path.insert(0, os.path.join(amici_dir, 'python', 'sdist'))
-
-    import amici
-# Works around some cyclic dependency issue with amici.petab_import_pysb
-import amici.petab_import
-
+import amici
 typing.TYPE_CHECKING = False
 
 
diff --git a/documentation/rtd_requirements.txt b/documentation/rtd_requirements.txt
index 37d6f7663c..dc598deaa0 100644
--- a/documentation/rtd_requirements.txt
+++ b/documentation/rtd_requirements.txt
@@ -1,3 +1,4 @@
+# NOTE: relative paths are expected to be relative to the repository root
 sphinx==5.1.1
 mock>=4.0.3
 setuptools==65.5.1
@@ -20,3 +21,4 @@ sphinxcontrib-napoleon>=0.7
 pygments==2.13.0
 Jinja2==3.1.2
 git+https://github.com/readthedocs/readthedocs-sphinx-ext
+-e python/sdist/
diff --git a/scripts/run-sphinx.sh b/scripts/run-sphinx.sh
index 933b8dc9cf..04716d4b7b 100755
--- a/scripts/run-sphinx.sh
+++ b/scripts/run-sphinx.sh
@@ -7,8 +7,8 @@ AMICI_PATH=$(cd $SCRIPT_PATH/.. && pwd)
 python3 -m venv ${AMICI_PATH}/doc-venv --clear
 source ${AMICI_PATH}/doc-venv/bin/activate
 python -m pip install --upgrade --no-cache-dir pip
-python -m pip install --exists-action=w --no-cache-dir -r ${AMICI_PATH}/documentation/rtd_requirements.txt
-python -m pip install --exists-action=w --no-cache-dir -r ${AMICI_PATH}/documentation/rtd_requirements2.txt
+(cd ${AMICI_PATH}/ && python -m pip install --exists-action=w --no-cache-dir -r documentation/rtd_requirements.txt)
+(cd ${AMICI_PATH}/ && python -m pip install --exists-action=w --no-cache-dir -r documentation/rtd_requirements2.txt)
 
 ${AMICI_PATH}/scripts/run-sphinx-hasenv.sh